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| 1 | Role of Hox genes in stem cell differentiation显示文摘Hox genes are an evolutionary highly conserved gene family. They determine the anterior-posterior body axis in bilateral organisms and influence the developmental fate of cells. Embryonic stem cells are usually devoidof any Hox gene expression, but these transcription factors are activated in varying spatial and temporal patterns defining the development of various body regions. In the adult body, Hox genes are among others responsible for driving the differentiation of tissue stem cells towards their respective lineages in order to repair and maintain the correct function of tissues and organs. Due to their involvement in the embryonic and adult body, they have been suggested to be useable for improving stem cell differentiations in vitro and in vivo. In many studies Hox genes have been found as driving factors in stem cell differentiation towards adipogenesis, in lineages involved in bone and joint formation, mainly chondrogenesis and osteogenesis, in cardiovascular lineages including endothelial and smooth muscle cell differentiations, and in neurogenesis. As life expectancy is rising, the demand for tissue reconstruction continues to increase. Stem cells have become an increasingly popular choice for creating therapies in regenerative medicine due to their self-renewal and differentiation potential. Especially mesenchymal stem cells are used more and more frequently due to their easy handling and accessibility, combined with a low tumorgenicity and little ethical concerns. This review therefore intends to summarize to date known correlations between natural Hox gene expression patterns in body tissues and during the differentiation of various stem cells towards their respective lineages with a major focus on mesenchymal stem cell differentiations. This overview shall help to understand the complex interactions of Hox genes and differentiation processes all over the body as well as in vitro for further improvement of stem cell treatments in future regenerative medicine approaches. | Anne Seifert David F Werheid Silvana M Knapp Edda Tobiasch | 2015 | World Journal of Stem Cells2015，7，3： | 10 |
| 2 | Susceptibility variations of multiple origins of loess from the Ily Basin(NW China)显示文摘The magnetic susceptibility of loess from the Ily Basin,northwestern China shows maximum values in S0 paleosols but minimum values in other paleosols,the mechanism of which has been well debated.In this work,systematic magnetic measurements were made on a representative section from Neleke county.The results show that the loess horizons(L1,L2 and L3) have multi-domain magnetite grains of aeolian origin,S0 is characterized by production of pedogenetic ultrafine-grained ferrimagnetic minerals,and the other paleosols(S1,S2,and S3) are characterized by the formation of nonferrimagnetic minerals associated with waterlogging.The correlation between the low concentration of ferrimagnets,high paramagnetic content,high magnetic coercivity remanence,fine ferrimagnetic grain size and intensified pedogenesis suggest two competing processes of pedogenetic enhancement and pedogenetic depletion in the lower paleosols.Pedogenetic depletion dominates and is responsible for the low susceptibility.Changes in magnetic grain size distribution occur during pedogenetic depletion.The susceptibility variations are of multiple origins in the loess of the Ily Basin.Pedogenetic enhancement,pedogenetic depletion,and allochthonous input of magnetic minerals should all be taken into account to explain the variations of magnetic parameters. | CHEN Qu LIU XiuMing HELLER F HIRT Ann M LU Bin GUO XueLian MAO XueGang ZHAO GuoYong FENG Hua GUO Hui | 2012 | Chinese Science Bulletin2012，57，15： | 9 |
| 3 | 伊犁黄土磁化率的增减及其成因显示文摘中国伊犁黄土磁化率一般在S0最高,但在其他古土壤层低,磁化率增减机制存在争议.对尼勒克县的一个剖面进行系统的磁学研究后发现,黄土层含有风成多畴磁铁矿,S0含有较多成壤成因的超细粒亚铁磁性矿物,其他古土壤层含有较多过湿条件下形成的非亚铁磁性矿物.非亚铁磁性矿物高含量、高矫顽力、亚铁磁性矿物低含量与较细的磁颗粒粒径对应于较高的成壤强度,揭示存在相互竞争的磁化率成壤增强过程和成壤削弱过程,以成壤削弱过程为主,导致磁化率降低.成壤削弱过程中,磁颗粒粒径发生变化.伊犁黄土磁化率变化成因多样,对磁学参数的解释要全面考虑磁性矿物的风成输入和成壤成因的磁性增强及磁性削弱作用. | 陈渠 刘秀铭 HELLER F HIRT Ann M 吕镔 郭雪莲 毛学刚 陈家胜 赵国永 丰华 郭晖 | 2012 | 科学通报2012，57，24： | 4 |
| 4 | Antioxidant activity of grape extracts in a lecithin liposome syste 显示文摘 | Ock-snook Y Anne S M Edwin N F | 1997 | JAOCS1997，74，10： | 1 |
| 5 | The GANA Program : A Tailoring Approach to Adapting Parent Child Interaction Therapy for Mexican Americans显示文摘 | Kristen M McCabe May Yeh Ann F Garland | 2005 | Education and Treatment of Children2005，28，2： | 1 |
| 6 | Further fatalities caused by anaphylactic reactions to food, 2001-2006 显示文摘 | Allan S Anne M F Hugh A S | 2007 | J Allergy ClinImmunol2007，119，4： | 1 |
| 7 | Structure and function of buffer strip s from a water quality perspective in agriculture landscapes显示文摘 | Lena B M Gilles P Ann F | 1995 | Landscape and Urban Planning1995，31，： | 1 |
| 8 | Further Fatalities Caused by Anaphylactic Reactions to Food, 2001-2006 显示文摘 | ALLAN BOCK S ANNE M F HUGH A S | 2007 | J Allergy Clin Immunol2007，119，4： | 1 |
| 9 | Diaphragm Muscle Remodeling in a Rat Model of Chronic Intermittent Hypox- ia显示文摘 | Christine M S Anne F Aidan B | 2013 | Histochem Cytochem2013，61，7： | 1 |
| 10 | Exogenous reelin prevents granule cell dispersion in experimental epilepsy显示文摘 | Martin C. Müller Matthias Osswald Stefanie Tinnes Ute H?ussler Anne Jacobi Eckart F?rster Michael Frotscher Carola A. Haas | 2009 | Experimental Neurology2009，，2： | 1 |
| 11 | Electrochemical property: Structure relationships in monoclinic Li3-yV2(P04)3 显示文摘 | YIN S C GRONDEY H STROBEL P ANNE M NAZAR L F | 2003 | Journal of the American Chemical Society2003，125，10： | 1 |
| 12 | The role of the technology acceptance model in explaining effects of image interactivity technology on consumer responses显示文摘 | Lee H H Ann M F Kim J H | 2006 | International Journal of Retail&Distribution Management2006，34，8： | 1 |
| 13 | Epidermal growth fac- tor receptor expression and gene copy number in fibrolamellar hep- atocellular carcinoma 显示文摘 | Anne F Buckley M D Lawrence J | 2006 | Hum Pathol2006，37，4： | 1 |
| 14 | Physical activity among adolescents in Taiwan 显示文摘 | CHEN L J M ANNE M H KENNETH R F | 2007 | Asia Pac J Clin Nutr2007，16，2： | 1 |
| 15 | Staging system for breast cancer: revisions for the 6th edition of the AJCC Cancer Staging Manual显示文摘 | S.Eva Singletary Craig Allred Pandora Ashley Lawrence W Bassett Donald Berry Kirby I Bland Patrick I Borgen Gary M Clark Stephen B Edge Daniel F Hayes Lorie L Hughes Robert V.P Hutter Monica Morrow David L Page Abram Recht Richard L Theriault Ann Thor Don | 2003 | Surgical Clinics of North America2003，，4： | 1 |
| 16 | Job satisfaction and its relationship to demographics and turnover of hotel food-service workers in Hong Kong 显示文摘 | Connie M Dori Ann F | 1986 | International Journal of Hospitality Management1986，，： | 1 |
| 17 | Osteopontin expression in lung cancer显示文摘 | SYLVIA M W NANCY K | 1996 | Lung Cancer1996，15，： | 1 |
| 18 | Stable transfer of intact high molecular weight DNA into plant chromosomes显示文摘 | Carol M H Anne F Candice L | 1996 | Proc Nat Acad Sci USA1996，93，： | 1 |
| 19 | Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2显示文摘 | Soncin F Zhang X Chu B Wang X Asea A Ann Stevenson M | 2003 | Biochem Biophys Res Commun2003，303，： | 1 |
| 20 | Structure and function of buffer strip s from a water quality perspective in agriculture landscapes 显示文摘 | Lena B M Gilles P Ann F | 1995 | Landscape and Urban Planning1995，31，13： | 1 |
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