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| 1 | Pancreatic metastases from renal cell carcinoma:The state of the art显示文摘Pancreatic metastases are rare,with a reported incidence varying from 1.6%to 11%in autopsy studies of patients with advanced malignancy.In clinical series,the frequency of pancreatic metastases ranges from 2%to 5%of all pancreatic malignant tumors.However,the pancreas is an elective site for metastases from carcinoma of the kidney and this peculiarity has been reported by several studies.The epidemiology,clinical presentation,and treatment of pancreatic metastases from renal cell carcinoma are known from singleinstitution case reports and literature reviews.Thereis currently very limited experience with the surgical resection of isolated pancreatic metastasis,and the role of surgery in the management of these patients has not been clearly defined.In fact,for many years pancreatic resections were associated with high rates of morbidity and mortality,and metastatic disease to the pancreas was considered to be a terminal-stage condition.More recently,a significant reduction in the operative risk following major pancreatic surgery has been demonstrated,thus extending the indication for these operations to patients with metastatic disease. | Roberto Ballarin Mario Spaggiari Nicola Cautero Nicola De Ruvo Roberto Montalti Cristina Longo Anna Pecchi Patrizia Giacobazzi Giuseppina De Marco Giuseppe D’Amico Giorgio Enrico Gerunda Fabrizio Di Benedetto | 2011 | World Journal of Gastroenterology2011，17，43： | 21 |
| 2 | Total and not bevacizumab-bound vascular endothelial growth factor as potential predictive factors to bevacizumab-based chemotherapy in colorectal cancer显示文摘AIM: To identify suitable biomarkers of response to bevacizumab(BV)- it remains an open question. The measurement of serum vascular endothelial growth factor(VEGF) has been proposed as a predictive factor for this drug, even if literature data are contradictory. METHODS: We prospectively evaluated the role of BV, total and not BV-bound VEGF and angiopoietin-2(Ang-2) serum levels as potential predictive factors of response for BV in combination with an oxaliplatinbased chemotherapy. BV, Ang-2, total and not BVbound VEGF levels were measured at baseline, before 2^(nd) and 5^(th) cycle of oxaliplatin-based chemotherapy in 20 consecutive metastatic colorectal cancer patients. RESULTS: Results were correlated to response to treatment. Variability in BV levels have been found, with decreased level in less responding patients. In particular, the concentration of BV increased of 3.96 ± 0.69 folds in serum of responsive patients after 3 more cycles of therapy compared to those with stable or progressive disease with a 0.72 ± 0.25 and 2.10 ± 0.13 fold increase, respectively. The determination of free and total VEGF demonstrated that the ratio between the two values, evaluated immediately before the 2^(nd) and the 5^(th) cycle of therapy, decreased from 26.65% ± 1.33% to 15.50% ± 3.47% in responsive patients and from 53.41% ± 4.75 to 34.95% ± 2.88% in those with stable disease. Conversely, in those with progression of disease, the ratio showed the opposite behavior coming up from 25.99% ± 5.23% to 51.71% ± 5.28%. The Ang-2 levels did not show any relationship. CONCLUSION: Our data show that the ratio of not BV-bound VEGF to total VEGF serum and BV plasma concentrations for predicting the response to BV plus oxaliplatin-based chemotherapy could be a promising biomarker of response to BV. | Amalia Azzariti Letizia Porcelli Oronzo Brunetti Marzia Del Re Vito Longo Patrizia Nardulli Michele Signorile Jian-Ming Xu Angela Calabrese Anna Elisa Quatrale Evaristo Maiello Vito Lorusso Nicola Silvestris | 2016 | World Journal of Gastroenterology2016，22，27： | 4 |
| 3 | Intestinal permeability test as a predictor of clinical course in Crohn’s disease显示文摘 | Renata D’Incà Vincenza Di Leo Giovanni Corrao Diego Martines Anna D’Odorico Cinzia Mestriner Carla Venturi Giuseppe Longo Giacomo Carlo Sturniolo | 1999 | The American Journal of Gastroenterology1999，，： | 2 |
| 4 | Potential therapeutic applications of mesenchymal stem cells for the treatment of eye diseases显示文摘Stem cell-based treatments have been extensively explored in the last few decades to develop therapeutic strategies aimed at providing effective alternatives for those human pathologies in which surgical or pharmacological therapies produce limited effects.Among stem cells of different sources,mesenchymal stem cells(MSCs)offer several advantages,such as the absence of ethical concerns,easy harvesting,low immunogenicity and reduced tumorigenesis risks.Other than a multipotent differentiation ability,MSCs can release extracellular vesicles conveying proteins,mRNA and microRNA.Thanks to these properties,new therapeutic approaches have been designed for the treatment of various pathologies,including ocular diseases.In this review,the use of different MSCs and different administration strategies are described for the treatment of diabetic retinopathy,glaucoma,and retinitis pigmentosa.In a large number of investigations,positive results have been obtained by in vitro experiments and by MSC administration in animal models.Most authors agree that beneficial effects are likely related to MSC paracrine activity.Based on these considerations,many clinical trials have already been carried out.Overall,although some adverse effects have been described,promising outcomes are reported.It can be assumed that in the near future,safer and more effective protocols will be developed for more numerous clinical applications to improve the quality of life of patients affected by eye diseases. | Giuliana Mannino Cristina Russo Anna Longo Carmelina Daniela Anfuso Gabriella Lupo Debora Lo Furno Rosario Giuffrida Giovanni Giurdanella | 2021 | World Journal of Stem Cells2021，13，6： | 2 |
| 5 | The Role of Liability, Regulation and Economic Incentives in Brownfield Re- mediation and Redevelopment: Evidence from Surveys of Devel- opers 显示文摘 | Anna Alberini Alberto Longo Stefania Tonin etc | 2005 | Reginal Science and Urban Economics2005，，4： | 1 |
| 6 | Intestinal permeability test as a predictor of clinical course in Crohn’s disease显示文摘 | Renata D'Incà Vincenza Di Leo Giovanni Corrao Diego Martines Anna D'Odorico Cinzia Mestriner Carla Venturi Giuseppe Longo Giacomo Carlo Sturniolo | 1999 | The American Journal of Gastroenterology1999，，10： | 1 |
| 7 | Effect of Lactobacillus GG and Breast-feeding in the Prevention of Rotavirus Nosocomial Infection显示文摘 | Emmanuele Mastretta Patrizia Longo Anna Laccisaglia Luciano Balbo Roberto Russo Alfonso Mazzaccara Paola Gianino | 2002 | Journal of Pediatric Gastroenterology and Nutrition2002，，4： | 1 |
| 8 | A novel microwave assisted process for the synthesis of nanostructured ruthenium catalysts active in the hydrogenation of phenol to cyc|ohexane显示文摘 | Galletti Anna Mafia Raspolli Antonetti Claudia Longo lginio | 2008 | Applied CatalysisA: General2008，350，1： | 1 |
| 9 | The role of liability, regulation and economic incentives in brown/ield remediatJon and redevelopment: evidence from surveys of developers显示文摘 | Anna Alberini Alberto Longo Stefanla Tonin | 2005 | Regional Science and Urban Economies2005，，35： | 1 |
| 10 | Combining the travel cost and contingent behavior methods to value cultural heritage sites: Evidence from Armenia 显示文摘 | Anna Alberini Alberto Longo | 2006 | J Cult Econ2006，30，： | 1 |
| 11 | Smart Meter Devices and the Effect of Feedback on Residential Electricity Consumption:Evidence from a Natural Experiment in Northern Ireland显示文摘 | Will Gans Anna Alberini Alberto Longo | 2013 | Energy Economics2013，，36： | 1 |
| 12 | Observatory science with eXTP显示文摘In this White Paper we present the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to Observatory Science targets. These include flaring stars, supernova remnants, accreting white dwarfs, low and high mass X-ray binaries, radio quiet and radio loud active galactic nuclei, tidal disruption events, and gamma-ray bursts. eXTP will be excellently suited to study one common aspect of these objects: their often transient nature. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Science, the eXTP mission is expected to be launched in the mid 2020s. | Jean J.M.in 't Zand Enrico Bozzo JinLu Qu Xiang-Dong Li Lorenzo Amati Yang Chen Immacolata Donnarumma Victor Doroshenko Stephen A.Drake Margarita Hernanz Peter A.Jenke Thomas J.Maccarone Simin Mahmoodifar Domitilla de Martino Alessandra De Rosa Elena M.Rossi Antonia Rowlinson Gloria Sala Giulia Stratta Thomas M.Tauris Joern Wilms XueFeng Wu Ping Zhou Iván Agudo Diego Altamirano Jean-Luc Atteia Nils A.andersson M.Cristina Baglio David R.Ballantyne Altan Baykal Ehud Behar Tomaso Belloni Sudip Bhattacharyya Stefano Bianchi Anna Bilous Pere Blay Joao Braga Sφren Brandt Edward F.Brown Niccolo Bucciantini Luciano Burderi Edward M.Cackett Riccardo Campana Sergio Campana Piergiorgio Casella Yuri Cavecchi Frank Chambers Liang Chen Yu-Peng Chen Jér?me Chenevez Maria Chernyakova ChiChuan Jin Riccardo Ciolfi Elisa Costantini Andrew Cumming Antonino D'Aì Zi-Gao Dai Filippo D'Ammando Massimiliano De Pasquale Nathalie Degenaar Melania Del Santo Valerio D'Elia Tiziana Di Salvo Gerry Doyle Maurizio Falanga XiLong Fan Robert D.Ferdman Marco Feroci Federico Fraschetti Duncan K.Galloway Angelo F.Gambino Poshak Gandhi MingYu Ge Bruce Gendre Ramandeep Gill Diego G?tz Christian Gouiffès Paola Grandi Jonathan Granot Manuel Güdel Alexander Heger Craig O.Heinke Jeroen Homan Rosario Iaria Kazushi Iwasawa Luca Izzo Long Ji Peter G.Jonker Jordi José Jelle S.Kaastra Emrah Kalemci Oleg Kargaltsev Nobuyuki Kawai Laurens Keek Stefanie Komossa Ingo Kreykenbohm Lucien Kuiper Devaky Kunneriath Gang Li En-Wei Liang Manuel Linares Francesco Longo FangJun Lu Alexander A.Lutovinov Denys Malyshev Julien Malzac Antonios Manousakis Ian McHardy Missagh Mehdipour YunPeng Men Mariano Méndez Roberto P.Mignani Romana Mikusincova M.Coleman Miller Giovanni Miniutti Christian Motch Joonas Nättilä Emanuele Nardini Torsten Neubert Paul T.O'Brien Mauro Orlandini Julian P.Osborne Luigi Pacciani Stéphane Paltani Maurizio Paolillo Iossif E.Papadakis Biswajit Paul Alberto Pellizzoni Uria Peretz Miguel A.Pérez Torres Emanuele Perinati Chanda Prescod-Weinstein Pablo Reig Alessandro Riggio Jerome Rodriguez Pablo Rodríguez-Gil Patrizia Romano Agata Rózańska Takanori Sakamoto Tuomo Salmi Ruben Salvaterra andrea Sanna andrea Santangelo Tuomas Savolainen Stéphane Schanne Hendrik Schatz LiJing Shao andy Shearer Steven N.Shore Ben W.Stappers Tod E.Strohmayer Valery F.Suleimanov Jirí Svoboda F.-K.Thielemann Francesco Tombesi Diego F.Torres Eleonora Torresi Sara Turriziani andrea Vacchi Stefano Vercellone Jacco Vink Jian-Min Wang JunFeng Wang Anna L.Watts ShanShan Weng Nevin N.Weinberg Peter J.Wheatley Rudy Wijnands Tyrone E.Woods Stan E.Woosley ShaoLin Xiong YuPeng Xu Zhen Yan George Younes WenFei Yu Feng Yuan Luca Zampieri Silvia Zane andrzej A.Zdziarski Shuang-Nan Zhang Shu Zhang Shuo Zhang Xiao Zhang Michael Zingale | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 0 |
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