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| 1 | Epidemiologic characteristics of Helicobacter pylori infection in southeast Hungary显示文摘BACKGROUND Epidemiologic studies have revealed a decrease in the prevalence of Helicobacter pylori(H.pylori)infection in Western Europe.AIM To obtain data regarding the prevalence of H.pylori in Csongrád and Békés Counties in Hungary,evaluate the differences in its prevalence between urban and rural areas,and establish factors associated with positive seroprevalence.METHODS One-thousand and one healthy blood donors[male/female:501/500,mean age:40(19–65)years]were enrolled in this study.Subjects were tested for H.pylori IgG antibody positivity via enzyme-linked immunosorbent assay.Subgroup analysis by age,gender,smoking habits,alcohol consumption,and urban vs nonurban residence was also performed.RESULTS The overall seropositivity of H.pylori was 32%.It was higher in males(34.93%vs 29.2%,P=0.0521)and in rural areas(36.2%vs 27.94%,P=0.0051).Agricultural/industrial workers were more likely to be positive for infection than office workers(38.35%vs 30.11%,P=0.0095)and rural subjects in Békés County than those in Csongrád County(43.36%vs 33.33%,P=0.0015).CONCLUSION Although the prevalence of H.pylori infection decreased in recent decades in Southeast Hungary,it remains high in middle-aged rural populations.Generally accepted risk factors for H.pylori positivity appeared to be valid for the studied population. | Lenke Bálint Andrea Tiszai Gábor Kozák Ilona Dóczi Veronika Szekeres Orsolya Inczefi Georgina Ollé Krisztina Helle Richárd Róka András Rosztóczy | 2019 | World Journal of Gastroenterology2019，25，42： | 5 |
| 2 | The Fanconi Anemia/ BRCA pathway: new faces in the crowd 显示文摘 | Kennedy RD D'Andrea AD | 2005 | Genes Dev2005，19，24： | 1 |
| 3 | Time-resolved fluorescence imaging in biology and medicine显示文摘 | Cubeddu RD Comelli CD Andrea | 2002 | J Phys D2002，35，： | 1 |
| 4 | Molecular characterisation of the Polycomblike gene of Drosophila melanogaster, a trans-acting negative regulator of homeotic gene expression显示文摘 | Lonie A Andrea RD Paro R | 1994 | Development1994，120，： | 1 |
| 5 | Whole blood platlet function in acute ischemic strole显示文摘 | Joseph RD Andrea C Wolch KW | 1989 | Stroke1989，20，： | 1 |
| 6 | Expression of angiogenic regulators,VEGF and leptin,is regulated by the EGF/PI3 K/STAT3 pathway in colorectal cancer cells显示文摘 | Cascio S Ferla RD Andrea A | | 0，，01： | 1 |
| 7 | A mutation of the common receptor subunit for interleukin-3(IL-3),granulocyte-macrophage colony-stimulating factor,and IL-5 that leads to ligand independence and tumorigenicity显示文摘 | RD′Andrea R Rayner J Moretti P | 1994 | Blood1994，83，10： | 1 |
| 8 | Reduced Stem Cell Factor Links Smooth Myopathy and Loss of Interstitial Cells of Cajal in Murine Diabetic Gastroparesis显示文摘 | Viktor J. Horváth Harsha Vittal Andrea L?rincz Hui Chen Gra?a Almeida–Porada Doug Redelman Tamás ?rd?g | 2006 | Gastroenterology2006，，3： | 1 |
| 9 | Molecular control of nitric oxide synthase in the cardiovascular system 显示文摘 | Andreas PA Rudic RD Sessa WC | 1999 | Cardiovasc Res1999，43，3： | 1 |
| 10 | DNA repair pathways in clinical prac-tice: lessons from pediatric cancer susceptibility syndromes 显示文摘 | Kennedy RD D'Andrea AD | 2006 | J ClinOncol2006，24，23： | 1 |
| 11 | The Fanconi Anemia/BRCA pathway:new faces in the crowd显示文摘 | Kennedy RD D' Andrea AD | 2005 | Genes Dev2005，19，24： | 1 |
| 12 | Molecular control of nitric oxide synthase in the cardiovascular system显示文摘 | Andreas PA Rudic RD Sessa WC | 1999 | Cardiovasc Rec1999，43，3： | 1 |
| 13 | Expressionofangiogenic regulators,VEGF and leptin, is regulated by the EGF/PI3 K/STAT3 pathway incolorectal cancer cells显示文摘 | Cascio S Ferla RD Andrea A | 2009 | J Cell Physiol2009，221，1： | 1 |
| 14 | Nutrition support in pancreatitis: beyond parenteral Nutrition 显示文摘 | Andrea J Yoder RD | 2003 | Prac Gastroen2003，9，1： | 1 |
| 15 | Clinical,histopathologic,and genetic features of pediatric primary myelofibrosis--an entity different from adults显示文摘 | Melissa RD Andrea MS Ramona A | | 0，，05： | 1 |
| 16 | International comparisons of mortality rates for cancer of the breast,ovary,prostate,and colon,and per capita food consumption显示文摘 | David P Rose Andrea P Boyar RD | 1986 | Cancer1986，，： | 1 |
| 17 | Validation of a surgical model for posthepatectomy liver failure in rats显示文摘Background:The upper limit for liver resections in rats is approximately 90%.In the early postoperative phase,mortality increases.The aim of the present study was to validate the rat model of 90%partial hepatectomy(PH)as a model of post-hepatectomy liver failure(PHLF).Further,we wanted to test a quantitative scoring system as a detector of lethal outcomes caused by PHLF in rats.Methods:Sixty-eight rats were randomized to 90%PH,sham operation,or no sur-gery.Further,block randomization was performed based on time of euthanization:12,24,or 48 h after surgery.A general distress score(GDS)≥10 during the day or≥6 at midnight prompted early euthanization and classification as nonsurvivor.Animals euthanized as planned were classified as survivors.During euthanization,blood and liver tissue were collected,and liver-specific biochemistry was evaluated.Results:Based on the biochemical results,all animals subjected to 90%PH expe-rienced PHLF.Seventeen rats were euthanized due to irreversible PHLF.The GDS increased for nonsurvivors within 12–18 h after surgery.The mean time for euthaniza-tion was 27 h after surgery.Conclusion:Based on the GDS and liver-specific biochemistry,we concluded that the model of 90%PH seems to be a proper model for investigating PHLF in rats.As a high GDS is associated with increased mortality,the GDS appears to be valuable in detect-ing lethal outcomes caused by PHLF in rats. | Andrea Lund Michelle Meier Kasper Jarlhelt Andersen Marie Ingemann Pedersen Anders Riegels Knudsen Jakob Kirkegård Frank Viborg Mortensen | 2023 | Animal Models and Experimental Medicine2023，6，3： | 0 |
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