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| 1 | saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription显示文摘 | Victoria Portnoy Szu Hua Sharon Lin Kathy H Li Alma Burlingame Zheng-Hui Hu Hao Li Long-Cheng Li | 2016 | Cell Research2016，26，3： | 6 |
| 2 | Proteomics Analysis Reveals Post-Translational Mechanisms for Cold-Induced Metabolic Changes in Arabidopsis显示文摘基因表示和新陈代谢的导致寒冷的变化是批评的让植物幸存结冰。主要由改变基因表示,到不会结冻的低温度的一个时期的暴露增加植物忍耐到作为冷环境适应知道的 freezinga 现象。在在结冰下面的温度落下指以前,寒冷也导致快速的新陈代谢的变化,它提供立刻的保护。为对寒冷的如此的快速的新陈代谢的回答的分子的机制仍然保持大部分未知。这里,我们使用 Arabidopsis thaliana proteome 的亚 cellular 部分的分析结合了的二维的差别胶化电气泳动(2-D DIGE ) 由双人脚踏车团 spectrometry 看到鉴定在 Arabidopsis 识别早寒冷应答的蛋白质。这些蛋白质包括涉及淀粉降级,三 HSP100 蛋白质,在 tricarboxylic 酸周期的几蛋白质,和蔗糖新陈代谢的四酶。在冷处理之上, Disproportionating 酶 2 (DPE2 ) ,使麦芽糖产生代射变化到葡萄糖的 cytosolic transglucosidase,在 centrifugation 小团部分很快增加了并且在可溶的部分减少了。与 DPE2 酶的活动的导致寒冷的 inactivation 一致,没有影响 C 重复有约束力的抄写因素(CBF ) , dpe2 异种显示出增加的结冰忍耐 transcriptional 小径。这些结果支持一个模型那导致寒冷的 inactivation DPE2 导致麦芽糖的快速的累积,它是保护房间免受结冰的伤害的导致寒冷的兼容溶质损坏。这研究为在对突然的温度的植物保护的新陈代谢的酶掉的糖类的快速的 translational 以后规定的一个关键角色提供证据。 | Tian Li Shou-Ling XU Juan A. Oses-Prieto Sunita Putil Peng Xu Rui-Ju Wang Kathy H. Li David A. Maltby Liz-He An Alma L. Burlingame Zhi-Ping Deng Zhi-Yong Wang | 2011 | Molecular Plant2011，4，2： | 6 |
| 3 | The Arabidopsis B-box protein BZS1/BBX20 interacts with HY5 and mediates strigolactone regulation of photomorphogenesis显示文摘Plant growth is controlled by integration of hormonal and light-signaling pathways. BZS1 is a B-box zinc finger protein previously characterized as a negative regulator in the brassinosteroid(BR)-signaling pathway and a positive regulator in the light-signaling pathway. However, the mechanisms by which BZS1/BBX20 integrates light and hormonal pathways are not fully understood. Here, using a quantitative proteomic workflow, we identified several BZS1-associated proteins, including light-signaling components COP1 and HY5. Direct interactions of BZS1 with COP1 and HY5 were verified by yeast two-hybrid and co-immunoprecipitation assays. Overexpression of BZS1 causes a dwarf phenotype that is suppressed by the hy5 mutation, while overexpression of BZS1 fused with the SRDX transcription repressor domain(BZS1-SRDX) causes a long-hypocotyl phenotype similar to hy5, indicating that BZS1's function requires HY5. BZS1 positively regulates HY5 expression, whereas HY5 negatively regulates BZS1 protein level, forming a feedback loop that potentially contributes to signaling dynamics. In contrast to BR,strigolactone(SL) increases BZS1 level, whereas the SL responses of hypocotyl elongation, chlorophyll and HY5 accumulation are diminished in the BZS1-SRDX seedlings, indicating that BZS1 is involved in these SL responses. These results demonstrate that BZS1 interacts with HY5 and plays a central role in integrating light and multiple hormone signals for photomorphogenesis in Arabidopsis. | Chuang-Qi Wei Chih-Wei Chien Lian-Feng Ai Jun Zhao Zhenzhen Zhang Kathy H. Li Alma L. Burlingame Yu Sun Zhi-Yong Wang | 2016 | Journal of Genetics and Genomics2016，43，9： | 5 |
| 4 | The Brassinosteroid-Activated BRI1 Receptor Kinase Is Switched off by Dephosphorylation Mediated by Cytoplasm-Localized PP2A B' Subunits显示文摘Brassinosteroid (BR ) 绑定由与它的合作受体 kinase BAK1 导致 heterodimerization 激活受体 kinase BRI1;然而, reversibly 使 BRI1 失去活性的机制仍然保持不清楚。这里,我们证明细胞质局部性的蛋白质磷酸酶 2A (PP2A ) B′regulatory 子单元与 BRI1 交往调停它的 dephosphorylation 和 inactivation。Loss-of-function 和 overexpression 实验显示出那一组 PP2A B′regulatory 子单元,由 B′ 代表了,否定地调整由减少的 BRI1 phosphorylation 发信号的 BR。BR 增加这些 B′subunits,和 B′ 的表示层次与 phosphorylated BRI1 优先地交往,建议 BR 发信号的动力学被 BRI1 的调停 PP2A 的反馈 inactivation 调制。与 PP2A B′ 相比并且 B′ ,它由 dephosphorylating 支持 BR 回答下游的抄写因素 BZR1,使 BRI1 失去活性 B′subunits 显示出类似的绑定到 BRI1 和 BZR1 但是不同 subcellular 本地化。B′subunits 的原子 / 细胞质的本地化的改变揭示了那细胞质的 PP2A dephosphorylates BRI1 并且禁止 BR 反应,而原子 PP2A dephosphorylates BZR1 并且激活 BR 反应。我们的调查结果不仅识别调停的 PP2A 规章的 B 子单元 BRI1 的绑定和 dephosphorylation,而且证明 PP2A 的 subcellular 本地化在 BR 发信号上指定它的底层选择和不同效果。 | Ruiju Wang Mengmeng Liu Min Yuan Juan A. Oses-Prieto Xingbo Cai Ying Sun Alma L. Burlingame Zhi-Yong Wang Wenqiang Tang | 2016 | Molecular Plant2016，9，1： | 5 |
| 5 | Proteomic Study Identifies Proteins Involved in Brassinosteroid Regulation of Rice Growth显示文摘Brassinosteroids (BRs) are essential hormones for growth and development of plant. In rice, BRs regulate multiple developmental processes and affect many important traits such as height, leaf angle, fertility and seed filling. We identified brassinosteroid-regulated proteins in rice using proteomic approaches and performed functional analysis of some BR-regulated proteins by overexpression experiments. Using two-dimensional difference gel electrophoresis (2-D DIGE) followed by protein identification by mass spectrometry, we compared proteomic differences in the shoots and roots of the BR-insensitive mutant d61-4 and BR-deficient mutant brd1-3. We identified a large number of proteins differentially expressed in the mutants compared with wild type control. These include a glycine-rich RNA-binding protein (OsGRP1) and a DREPP2 protein, which showed reduced levels in the BR mutants. Overexpression of these two proteins partially suppressed the dwarf phenotype of the Arabidopsis BR-insensitive mutant bri1-5. In contrast to the reduced protein level, the RNA level of OsGRP1 was not significantly affected in the BR mutants or by BR treatment, suggesting BR regulation of OsGRP1 at the posttranslational level. This study identifies many BR-regulated proteins and demonstrates that OsGRP1 functions downstream in the BR signal transduction pathway to promote cell expansion. | Fengru Wang Ming-Yi Bai Zhiping Deng Juan A. Oses-Prieto Alma L. Burlingame Tiegang Lu Kang Chong Zhi-Yong Wang | 2010 | Journal of Integrative Plant Biology2010，52，12： | 4 |
| 6 | Volatile compo-nents of roasted Peanuts: Basic Fraction显示文摘 | B R Johnson George R Waller Alma L Burlingame | 1971 | Agric food chem1971，19，5： | 1 |
| 7 | Glucose Sensor O -GlcNAcylation Coordinates with Phosphorylation to Regulate Circadian Clock显示文摘 | Krista Kaasik Saul Kivim?e Jasmina J. Allen Robert J. Chalkley Yong Huang Kristin Baer Holger Kissel Alma L. Burlingame Kevan M. Shokat Louis J. Ptá?ek Ying-Hui Fu | 2013 | Cell Metabolism2013，，2： | 1 |
| 8 | Immunopurification and Mass Spectrometry Identifies Protein Phosphatase 2A (PP2A) and BIN2/GSK3 as Regulators of AKS Transcription Factors in Arabidopsis显示文摘 | Bu, Shuo-Lei Liu, Chao Liu, Ning Zhao, Ji-Long Ai, Lian-Feng Chi, Hao Li, Kathy L. Chien, Chih-Wei Burlingame, Alma L. Zhang, Sheng-Wei Wang, Zhi-Yong | 2017 | Molecular Plant2017，10，2： | 1 |
| 9 | Chemical Genetic Identification of NDR1/2 Kinase Substrates AAK1 and Rabin8 Uncovers Their Roles in Dendrite Arborization and Spine Development显示文摘 | Sila K. Ultanir Nicholas T. Hertz Guangnan Li Woo-Ping Ge Alma L. Burlingame Samuel J. Pleasure Kevan M. Shokat Lily Yeh Jan Yuh-Nung Jan | 2012 | Neuron2012，，： | 1 |
| 10 | Detection of (3'-hydroxy)-3,N4-benzetheno-2'-deoxycytidine-3'-phosphate by 32P-postlabeling of DNA reacted with p-benzoquinone显示文摘 | Krisztina Pongracz Surinder Kaur Alma L Burlingame | 1990 | Carcinogenesis1990，11，9： | 1 |
| 11 | Quantitative proteomic analysis of Huh-7 cells infected with Dengue virus by label-free LC–MS显示文摘 | Victoria Pando-Robles Juan A. Oses-Prieto Myriam Rodríguez-Gandarilla Erika Meneses-Romero Alma L. Burlingame Cesar V.F. Batista | 2014 | Journal of Proteomics2014，，： | 1 |
| 12 | XENOBIOTICALLY MODIFIED HUMAN HEMOGLOBIN STUDIED BY ELECTROSPRAY MASS SPECTROMETRY显示文摘XENOBIOTICALLYMODIFIEDHUMANHEMOGLOBINSTUDIEDBYELECTROSPRAYMASSSPECTROMETRY￥XiaoBaiXU;SurinderKAUR;DavidMALTBY;AlmaBURLINGAME1... | Xiao Bai XU Surinder KAUR David MALTBY Alma BURLINGAME 1 (Research Center for Eco-environmental Sciences.Academia Sinica, Beijing, 100085)2 (Mass Spectrometry Facility Laboratory, Department of Pharmaceutical Chemistry, UC San Francisco CA 94143, USA) | 1995 | Chinese Chemical Letters1995，6，5： | 0 |
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