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Identification of long non-coding RNA p34822 as a potential plasma biomarker for the diagnosis of hepatocellular carcinoma

查看全文 作  者:Cheng [1,2]Wang;Tianyu [2]Ren;Keyu [3]Wang;Shaogeng [2]Zhang;Shubin [1]Liu;Hu [1]Chen;Penghui [2,3]Yang 高影响力作者 机构地区:[1]The 307 Hospital Of PLA, Beijing 100071, China;[2]The 302 Hospital Of PLA, Beijing 100039, China;[3]Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing 100071, China高影响力机构 出  处:《Science China(Life Sciences)》索引2017年第60卷第9期,共4页高影响力期刊 基  金:supported by the Natural Science Foundation of Beijing Municipality(CN7162185) 摘  要:Dear Editor,Hepatocellular carcinoma(HCC)is the third leading cause of cancer-related deaths worldwide(Li and Satomura,2015).Early diagnosis and treatment are vital for reducing mortality.Currently,biomarkers such as serum alpha fetoprotein(AFP),AFP-L2,and carcinoembryonic antigen are widely used tumor markers for managing HCC in patients(Shi et al.,2016).However,because of their low diagnostic sensitivity and specificity,novel biomarkers with high sensitivity and specificity for early HCC diagnosis are needed. 关 键 词:原发性肝细胞癌 生物标志物 早期诊断 非编码RNA 鉴定 血浆 肿瘤标志物 早期治疗
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