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Risk factors of gastroesophageal reflux disease in Shiraz,southern Iran

查看全文 作  者:Mehdi Saberi-[1]Firoozi;Farnaz [1]Khademolhosseini;Maryam [1]Yousefi;Davood [1]Mehrabani;Najaf [2]Zare;Seyed Taghi [3]Heydari 高影响力作者 机构地区:[1]Gastroenterohepatology Research Center/Department of Internal Medicine,Nemazee Hospital,School of Medicine,Shiraz University of Medical Sciences,Shiraz,Iran;[2]Department of Biostatistics,School of Public Health,Shiraz University of Medical Sciences,Shiraz,Iran;[3]Gastroenterohepatology Research Center/Department of Internal Medicine,Nemazee Hospital,School of Medicine,Shiraz University of Medical Sciences,Shiraz,Iran Department of Biostatistics,Lorestan University of Medical Sciences,Khoramabad,Iran高影响力机构 出  处:《World Journal of Gastroenterology》索引2007年第13卷第41期,共6页高影响力期刊 摘  要:AIM: To determine the prevalence and symptoms of gastroesophageal reflux disease (GERD) in a healthy general population in relation to demographic,lifestyle and health-seeking behaviors in Shiraz,southern Iran. METHODS: A total of 1978 subjects aged > 35 years who referred to Gastroenterohepatology Research Center and who completed a questionnaire consisting of 27 questions for GERD in relation to demographic,lifestyle and health-seeking behaviors were included in this study for a period of five months. The validity and reliability of the questionnaire were determined. RESULTS: The prevalence of GERD was 15.4%,which was higher in females (17.3%),in rural areas (19.8%),and in illiterate subjects (21.5%) and those with a mean age of 50.25 years. The prevalence was significantly lower in subjects having fried food (14.8%),and fruit and vegetables (14.6%). More symptoms were noticed in subjects consuming pickles (22.1%),taking aspirin (21%) and in subjects with psychological distresses (27.2%) and headaches (22%). The correlation was statistically significant between GERD and halitosis (18.3%),dyspepsia (30.6%),anxiety (19.5%),nightmares (23.9%) and restlessness (18.5%). Their health seeking behavior showed that there was a significant restriction of diet (20%),consumption of herbal medicine (19%),using over-the-counter drugs (29.9%) and consulting with physicians (24.8%). Presence of GERD symptoms was also significantly related to a previous family history of the disease (22.3%).CONCLUSION: GERD is more common in females,rural and illiterate subjects and correlated with consumption of pickles,occurrence of headache,psychological distress,dyspepsia,halitosis,anxiety,nightmare and restlessness,and a family history of GERD and aspirin intake,but the correlation was negative with consumption of fat and fiber intake. 关 键 词:胃食管回流 风险因素 设拉子 伊朗
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