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1High-yield preparation of robust gold nanoshells on silica nanorattles with good biocompatiblity显示文摘Although gold nanoshells are widely considered as one of the promising photothermal nanomaterials used for biomedicine, the high cost, low yield and poor stability severely limit their potential application in clinical trials.Herein, robust gold nanoshells on silica nanorattles(GSNs)were easily prepared in a high yield by an improved seedmediated method employing polyvinylpyrrolidone(PVP) as a stabilizing and capping agent. The present method is very simple, effective and reproducible and can well control the growth process of gold nanoshells. The as-prepared GSNs have a narrow size distribution(<10 % in standard deviation). Furthermore, the utilization rate of Au in the solution used for the growth of gold nanoshells increases by 70 %than that in previous method. The resultant GSNs have a good structural stability after placing over 6 months due to the protection of PVP. More importantly, in vivo and in vitro toxic studies indicate that the GSNs have good biocompatibility. We believe that our preparation method will remarkably promote the use of gold nanoshells for biomedicine.Changhui Fu Chaofeng He Longfei Tan Shunhao Wang Lu Shang Linlin Li Xianwei Meng Huiyu Liu 2016Science Bulletin2016,61,4:5
2Piecewise Linear Weighted Iterative Algorithm for Beam Alignment in Scanning Beam Interference Lithography显示文摘To obtain a good interference fringe contrast and high fidelity,an automated beam iterative alignment is achieved in scanning beam interference lithography(SBIL).To solve the problem of alignment failure caused by a large beam angle(or position)overshoot exceeding the detector range while also speeding up the convergence,a weighted iterative algorithm using a weight parameter that is changed linearly piecewise is proposed.The changes in the beam angle and position deviation during the alignment process based on different iterative algorithms are compared by experiment and simulation.The results show that the proposed iterative algorithm can be used to suppress the beam angle(or position)overshoot,avoiding alignment failure caused by over-ranging.In addition,the convergence speed can be effectively increased.The algorithm proposed can optimize the beam alignment process in SBIL.Ying SONG Bayanheshig Shuo LI Shan JIANG Wei WANG 2019Photonic Sensors2019,9,4:0
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