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| 1 | Chest CT features of children infected by B.1.617.2 (Delta) variant of COVID‑19显示文摘Background This study aimed to explore the imaging characteristics,diversity and changing trend in CT scans of pediatric patients infected with Delta-variant strain by studying imaging features of children infected with Delta and comparing the results to those of children with original COVID-19.Methods A retrospective,comparative analysis of initial chest CT manifestations between 63 pediatric patients infected with Delta variant in 2021 and 23 pediatric patients with COVID-19 in 2020 was conducted.Corresponding imaging features were analyzed.In addition,the changing trend in imaging features of COVID-19 Delta-variant cases were explored by evaluating the initial and follow-up CT scans.Results Among 63 children with Delta-variant COVID-19 in 2021,34(53.9%)showed positive chest CT presentation;and their CT score(1.10±1.41)was signifcantly lower than that in 2020(2.56±3.5)(P=0.0073).Lesion distribution:lung lesions of Delta cases appear mainly in the lower lungs on both sides.Most children had single lobe involvement(18 cases,52.9%),14(41.2%)in the right lung alone,and 14(41.2%)in both lungs.A majority of Delta cases displayed initially ground glass(23 cases,67.6%)and nodular shadows(13 cases,38.2%)in the frst CT scan,with few extrapulmonary manifestations.The 34 children with abnormal chest CT for the frst time have a total of 92 chest CT examinations.These children showed a statistically signifcant diference between the 0-3 day group and the 4-7 day group(P=0.0392)and a signifcant diference between the 4-7 day group and the more than 8 days group(P=0.0003).Conclusions The early manifestations of COVID-19 in children with abnormal imaging are mostly small subpleural nodular ground glass opacity.The changes on the Delta-variant COVID-19 chest CT were milder than the original strain.The lesions reached a peak on CT in 4-7 days and quickly improved and absorbed after a week.Dynamic CT re-examination can achieve a good prognosis. | Qi-Rui Cheng Ming-Xing Fan Jing Hao Xiao-Chen Hu Xu-Hua Ge Zhi-Liang Hu Zhuo Li | 2022 | World Journal of Pediatrics2022，18，1： | 2 |
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