| 1 | Nanoparticles modified by polydopamine: Working as “drug” carriers显示文摘Inspired by the mechanism of mussel adhesion,polydopamine(PDA),a versatile polymer for surface modification has been discovered.Owing to its unique properties like extraordinary adhesiveness,excellent biocompatibility,mild synthesis requirements,as well as distinctive drug loading approach,strong photothermal conversion capacity and reactive oxygen species(ROS)scavenging facility,various PDA-modified nanoparticles have been desired as drug carriers.These nanoparticles with diverse nanostructures are exploited in multifunctions,consisting of targeting,imaging,chemical treatment(CT),photodynamic therapy(PDT),photothermal therapy(PTT),tissue regeneration ability,therefore have attracted great attentions in plenty biomedical applications.Herein,recent progress of PDA-modified nanoparticle drug carriers in cancer therapy,antibiosis,prevention of inflammation,theranostics,vaccine delivery and adjuvant,tissue repair and implant materials are reviewed,including preparation of PDA-modified nanoparticle drug carriers with various nanostructures and their drug loading strategies,basic roles of PDA surface modification,etc.The advantages of PDA modification in overcoming the existing limitations of cancer therapy,antibiosis,tissue repair and the developing trends in the future of PDA-modified nanoparticle drug carriers are also discussed. | Anting Jin Yitong Wang Kaili Lin Lingyong Jiang | 2020 | Bioactive Materials2020，5，3： | 13 |
| 2 | 诺氟沙星分子印迹共混膜的制备及应用显示文摘本文以诺氟沙星为模板分子,甲基丙烯酸为功能单体,乙二醇二甲基丙烯酸酯为交联剂,采用本体聚合法制备分子印迹聚合物,与聚砜铸膜液混合,制备出可以在低压力下对诺氟沙星有特异性截留作用的分子印迹共混膜。采用红外光谱对共混膜的结构进行表征,利用扫描电子显微镜对共混膜微观形貌进行表征。研究了聚合物的质量分数对共混膜水通量和截留率的影响,选出最佳混合比例并考察了选择性透过率。结果表明,当聚合物添加量为63.84%时,分子印迹基膜具有良好的支撑能力和较大的水通量。基于该基膜所制备的诺氟沙星分子印迹共混膜水通量为272.34 L·m^(−2)·h^(−1)(操作压力0.2 MPa),对诺氟沙星截留率为89.47%,具有很好的去除效果。 | 蒋育杉 张林楠 张红 周强 王颜红 | 2022 | 环境化学2022，41，3： | 0 |
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