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1Antifertility effect of ethanolic extract of Amalakyadi churna in male albino mice显示文摘Aim: To evaluate the antifertility activity of the ethanolic extract of Amalakyadi churna by oral administra-tion in male albino mice. Methods: The ethanol extract of Amalakyadi churna at the dose of 250 mg/kg and 400 mg/kg body weight was administered orally for 30 days to adult male mice. On day 31, the mice were sacrificed and the testis and accessory reproductive organs were removed and weighed. The organs were processed for biochemical estimation and histological work. Results: Treatment with Amalakyadi chuma resulted in decrease in the weights of testis and accessory reproductive organs. The diameters of testis, seminiferous tubules and Leydig cell nucleus were decreased. The spermatogenic elements, like spermatogonia, spermatocytes and spermatids in the testis were re-duced significantly as well as the sperm count in cauda epididymis. There was a significant reduction in the protein,glycogen, DNA and RNA contents and the activity of acid phosphatase in the testis of extract treated mice compared with the control. The cholesterol content and the alkaline phophatase activity were increased significantly in treated mice. Conclusion: Amalakyadi churna extract arrests spermatogenesis in male mice without noticeable side effects.(Asian J Andro12003 Sep; 5: 247-250)Y.N.Seetharam H.Sujeeth G.Jyothishwaran Arvind Barad G.Sharanabasappa B.Umareddy M.B.Vijaykumar Saraswati B.Patil 2003Asian Journal of Andrology2003,5,3:3
2Effect of piperine on the epididymis of adult male rats显示文摘瞄准:在成年雄的老鼠的附睾抗氧化剂系统上学习胡椒碱的效果。方法:成年雄的老鼠每天是在 1 mg/kg, 10 mg/kg 和 100 mg/kg 体重的剂量的口头上地管理的胡椒碱 30 连续的天了。在最后治疗以后的 24 个小时,老鼠与醚和附睾被称并且杀死从身体被把。从附睾的尾区域收集的精子被用于对它的计数,活动性和生存能力的评价。头,语料库和附睾的尾区域被分开并且独立一致获得 10 % homogenates。上层清液被用于涎的的酸的、超级氧化物歧化酶的试金,过氧化氢酶,谷胱甘肽过氧化物酶,谷胱甘肽还原酶,类脂化合物每氧化和过氧化氢产生。结果:对待胡椒碱的老鼠的体重仍然保持未改变。头,语料库和附睾的尾区域的重量显著地在 100 mg/kg 的剂量减少了。附睾精子计数和活动性在 10 mg/kg 和 100 mg/kg 减少了,并且精子生存能力在 100 mg/kg 显著地减少了。当在尾区域的重要减少独自在 10 mg/kg 被观察时,在附睾的涎的酸层次在 100 mg/kg 显著地减少了。在超级氧化物歧化酶,过氧化氢酶,谷胱甘肽过氧化物酶和谷胱甘肽还原酶的活动的重要衰落,与过氧化氢的增加一起,产生和类脂化合物在 10 mg/kg 和 100 mg/kg 每氧化被观察。结论:在抗氧化剂酶和涎的酸的活动引起减少的胡椒碱在附睾和能损坏附睾环境和精子功能的从而增加的反应的氧种类层次铺平。S.C.D'cruz P.P.Mathur 2005Asian Journal of Andrology2005,7,4:2
3Clinical trial of Butea superba, an alternative herbal treatmentfor erectile dysfunction显示文摘Aim: To study the effect of Butea superba on erectile dysfunction (ED) in Thai males. Methods: A 3-month randomized double-blind clinical trial was carried out in volunteers with ED, aged 30 years-70 years, to evaluate the therapeutic effect of the crude preparation of Butea superba tubers on ED. Results: There was a significant upgrading in 4 of the 5 descriptive evaluations of the IIEF-5 questionnaire. Estimation of the sexual record indicated that 82.4 % of the patients exhibited noticeable improvement. Haematology and blood chemistry analysis revealed no apparent change. Conclusion: The plant preparation appears to improve the erectile function in ED patients without apparent toxicity. ( Asian J Andro12003 Sep; 5: 243-246)W.Cherdshewasart N.Nimsakul 2003Asian Journal of Andrology2003,5,3:2
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