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| 1 | Decidual natural killer cells and the immune microenvironment at the maternal-fetal interface显示文摘During early pregnancy,an orchestrated evolutionary maternal adaption toward tolerance of the semiallogeneic fetus is required to ensure decidualization and early embryo development.Remodeling of the immune system involves natural killer cells(NKs),macrophages,T cells and dendritic cells(DCs) altering the microenvironment in the deciduas.In particular,a unique population of NK cells with a CD56^(bright)CD16^- phenotype in the decidua has been proposed to play a key role in the maternal adaptation to pregnancy.However,there is a tendency for pregnancy immunology to reflect transplantation immunology regarding the assumption that the maternal immune system should be suppressed.This tendency is misleading.We discuss how the immune system is formed in early deciduas and the interactions between maternal NK cells and fetal growth.We propose that the maternal immune response must not be fully suppressed and is even necessary for the local response of uterine NK cells. | Binqing Fu Haiming Wei | 2016 | Science China(Life Sciences)2016，59，12： | 15 |
| 2 | 血浆标志物与ST段抬高型急性心肌梗死患者住院期间主要不良心脏事件相关性研究显示文摘目的检测ST段抬高型急性心肌梗死(STEAMI)患者血浆心肌肌钙蛋白I(cTnI)、精氨酸-加压素(AVP)、和肽素(COP)、心钠肽(ANP)、脑钠肽(BNP)、氨基末端脑钠肽原(NT-proBNP)和肾上腺素髓质素(ADM)浓度,探讨其对心肌梗死患者住院期间主要不良心脏事件(MACE)发生的预测价值。方法收集STEAMI患者和健康体检者各118例,ELISA法检测血浆cTnI、AVP、COP、ANP、BNP、NT-proBNP和ADM浓度,评价和比较其对急性心肌梗死患者住院期间主要MACE发生的预测价值。结果STEAM患者血浆cTnI、AVP、COP、ANP、BNP、NT-proBNP和ADM浓度均显著高于健康体检者(均P<0.01)。35例(29.7%)出现MACE。MACE患者血浆中上述激素的浓度均显著高于无MACE患者(均P<0.01)。ROC曲线分析显示,血浆中这些激素水平均可显著预测住院期间MACE发生(均P<0.01),而COP及NT-proBNP的预测价值优于cTnI(均P<0.05)。联合检测血浆COP及NT-proBNP可进一步提高血浆COP及NT-proBNP单独检测的预测价值(均P<0.05)。结论血浆COP及NT-proBNP浓度对STEAMI患者住院期间主要不良心脏事件的预测价值较高,而联合检测血浆COP及NT-proBNP浓度更具有临床价值。 | 汤蓓 钟泽 吴新东 相鹏 沈红卫 | 2015 | 浙江医学2015，37，15： | 11 |
| 3 | Reproductive Immunology Issue 2: Cellular and Molecular Biology显示文摘 | Guest Editor B Anne Croy | 2014 | Cellular & Molecular Immunology2014，11，6： | 1 |
| 4 | Reproductive Immunology Issue One: Cellular and Molecular Biology显示文摘 | Guest Editor B Anne Croy | 2014 | Cellular & Molecular Immunology2014，11，5： | 0 |
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