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| 1 | 阴茎延长中使用V-Y成形术是否必要?介绍一种新的手术方式:单纯冠状沟下环形切口阴茎延长增粗术显示文摘本研究介绍了一种新的通过冠状沟下环形切口的悬韧带松解术,并确定其安全性和有效性。过去的7年中,我们连续做了82例阴茎增粗术。前35例男性患者接受下腹部V-Y成形切口韧带松解术(A组),后续47例男性患者接受冠状沟下环形切口韧带松解术(B组)。我们比较了两组手术时间、手术并发症和手术前后的阴茎长度和周径值以及手术前后的自信心、满意度评分。患者平均年龄为32岁(18—56岁)。79例患阴茎短小综合征,3例为小阴茎(牵拉长度〈7.5厘米)。A组和B组的平均手术时间分别为150.7分钟和125.2分钟(P=0.005)。4例(11%)A组患者和3例(6%)B组患者术后分别出现了阴茎回缩(P=0.453)。18例(51%)A组患者出现了手术瘢痕增生,而在环形切口手术组则未观察到明显切口并发症。两者阴茎长度和周径改善效果相当。但环形切口手术组满意度和自尊心和性关系问卷(SEAR)改善程度更高(P值分别为0.007和〈0.001)。在严格的病例筛选标准下,与V-Y成形术相比较,环形切口悬韧带松解术在安全性、手术时间、阴茎回缩率和外观方面均有改善,而在阴茎大小改善效果上无差异。 | Nikos Mertziotis Diomidis Kozyrakis Elias Bogris | 2013 | Asian Journal of Andrology2013,15,6: | 5 |
| 2 | 自体睾丸鞘膜移植治疗阴茎硬结症显示文摘目的:探讨自体睾丸鞘膜移植治疗阴茎硬结症的手术效果。方法:10例阴茎硬结症患者,采用自体睾丸鞘膜移植阴茎成形术进行治疗,并在术前以及术后1年和5年接受IIEF-5问卷评分。结果:10例患者术后阴茎均能恢复正常勃起形态,阴茎勃起疼痛症状消失,阴茎弯曲明显减轻,无复发性ED,能进行满意的性生活,IIEF-5评分在术后1年和5年分别为(22.40±1.08)、(22.80±1.14)分,均显著高于术前[(19.20±2.28)分,P均<0.05]。结论:自体睾丸鞘膜移植术治疗阴茎阴茎硬结症造成的勃起畸形是一种安全、简便、经济、有效的手术方式,然而需要进一步大样本的研究来证实。 | 王亚民 宋乐彬 张嘉宜 陈晨 王仪春 秦超 王增军 宋宁宏 | 2016 | 中华男科学杂志2016,22,7: | 4 |
| 3 | 斑块切除加自体睾丸鞘膜移植术治疗阴茎硬结症显示文摘目的:探讨斑块切除+自体睾丸鞘膜移植术治疗阴茎硬结症的临床疗效。方法:选取2013年1月至2015年12月收治的10例经药物保守治疗12个月以上无效、处于稳定期6个月以上、阴茎弯曲>60°、不能完成性交的阴茎硬结症患者,行阴茎硬结切除+自体睾丸鞘膜移植修补缺损。结果:10例患者术后随访期6~24个月,所有患者术后阴茎均能正常勃起,无手术侧睾丸萎缩、扭转或坏死。患者对阴茎外形满意,未觉阴茎有明显缩短。结论:斑块切除+自体睾丸鞘膜移植术是治疗阴茎硬结症造成的阴茎勃起畸形的一种安全、简便、经济和有效的手术方式。 | 李志刚 臧光辉 郝林 赵岩 周荣升 韩从辉 | 2018 | 中华男科学杂志2018,24,1: | 3 |
| 4 | Modern treatment strategies for penile prosthetics in Peyronie’s disease:a contemporary clinical review显示文摘Peyronie's disease is a common condition resulting in penile deformity,psychological bother,and sexual dysfunction.Erectile dysfunction is one common comorbid condition seen in men with Peyronie’s disease,and its presence significantly impacts treatment considerations.In a man with Peyronie's disease and significant erectile dysfunction who desires the most reliable treatment,penile prosthesis placement should be strongly considered.In some instances,such as those patients with relatively mild curvature,prosthesis placement alone may result in adequate straightening.However,many patients will require additional straightening maneuvers such as manual modeling,penile plication,and tunica albuginea incision with or without grafting.For patients with severe penile shortening,penile length restoration techniques may also be considered.Herein,we provide a comprehensive clinical review of penile prosthesis placement in men with Peyronie's disease.Specifically,we discuss preoperative indications,intraoperative considerations,adjunctive straightening maneuvers,and postoperative outcomes. | Matthew J Ziegelmann M Ryan Farrell Laurence A Levine | 2020 | Asian Journal of Andrology2020,22,1: | 2 |
| 5 | 应用人脱细胞异体真皮(HADM)治疗阴茎硬结症合并弯曲畸形的可行性分析显示文摘目的探讨采用人脱细胞异体真皮(human acellular dermal mantrix,HADM)在阴茎硬结症合并阴茎弯曲患者斑块剜除后修补白膜缺损的可行性。方法17例阴茎硬结症患者,侧方弯曲10例,向背侧弯曲6例,向腹侧弯曲1例,采用人脱细胞异体真皮作为补片材料行阴茎海绵体斑块切除阴茎白膜缺损修补手术,并在术前及术后3、6、12月接受IIEF-5问卷评分及RigiScan检测(NPTR模式)。结果17例患者术后阴茎均能恢复正常勃起形态、阴茎勃起疼痛症状消失、阴茎无明显弯曲畸形及硬结复发;部分患者阴茎干早期有感觉迟钝及感觉减退、勃起时牵拉疼痛等不适,半年后消失;术后5例对阴茎长度不满意,没有观察到相关合并症;3例患者术后性功能相比术前减退,予以PDE5i治疗后好转,14例术后性功能相比术前提高,均能完成满意的性生活;患者及性伴侣满意度均高。IIEF-5评分在术后3、6、12月分别为(20.20±1.26)、(22.60±1.08)、(22.80±1.14)分,均显著高于术前(18.20±1.88)分,P<0.05,术后6月及12月无统计学差异;RigiScan头端平均勃起硬度数据在术后3月、6月及12月分别为(60.25±2.08%)、(69.44±2.14%)、(70.22±1.48%)均高于术前(50.78±2.24%),P<0.05;术后6月及12月无统计学差异。结论利用HADM修复阴茎硬结症合并重度弯曲斑块切除后安全有效,但是需要开展随机双盲,其他移植物对照的研究。 | 郭巍 陈琦炜 蒋冠军 | 2020 | 中国男科学杂志2020,34,3: | 1 |
| 6 | 体外冲击波与自体睾丸鞘膜移植术治疗阴茎硬结症的效果比较显示文摘目的比较分析经体外冲击波与自体睾丸鞘膜移植术两组治疗方式对阴茎硬结症的临床效果。方法选取2010年6月~2016年1月徐州市中心医院收治的20例诊断阴茎硬结症的患者,按照随机数法分为对照组和观察组,每组各10例。对照组行体外冲击波治疗,观察组行自体睾丸鞘膜移植术。比较两组治疗前后国际勃起功能指数(IIEF-5)、硬结大小及阴茎弯曲度。结果对照组治疗前后IIEF-5评分、硬结大小及阴茎弯曲度比较,差异无统计学意义(P> 0.05)。治疗后观察组IIEF-5评分较治疗前明显升高,差异有统计学意义(P <0.05);硬结在治疗后消失,治疗前后硬结大小比较,差异有统计学意义(P <0.05);治疗后阴茎弯曲度低于治疗前,差异有统计学意义(P <0.05)。两组治疗后的IIEF-5评分、硬结大小及阴茎弯曲度比较,差异均有统计学意义(P <0.05)。结论体外冲击波治疗阴茎硬结症的效果仍存在疑议,自体睾丸鞘膜移植术是治疗阴茎硬结症安全有效的手术方式。 | 朱广远 张治国 张文达 韩从辉 | 2018 | 中国医药导报2018,15,31: | 0 |
| 7 | Effects of patients'understanding and choice of surgical types on postoperative outcomes of Peyronie’s disease:a single-center retrospective study of 108 patients显示文摘Surgical correction can be considered for treating patients with a chronic phase of Peyronie’s disease(PD)and persistent penile curvature.In clinical practice,some patients pay too much attention to surgical complications and refuse the recommended feasible surgical types.Meanwhile,they require operations according to their preferences.This study aimed to evaluate the effects of patients’own choice of surgical type on postoperative satisfaction.This retrospective study analyzed data from 108 patients with PD who underwent surgical correction according to doctors’recommendations or patients’own demands.The objective and subjective surgical outcomes were assessed.Patients1 understanding of the disease was analyzed using a questionnaire survey.Objective measurements of surgical outcomes,including penile straightening,penile length,and sexual function,in patients who received the recommended surgery,were similar to those in patients who did not accept the recommended surgery.However,subjective evaluations,including erectile pain,discomfort because of nodules on the penis,and decreased sensitivity in the penis,were more obvious in patients who did not follow doctors’recommendations.In addition,a questionnaire survey showed that understanding PD and the purpose of surgery of patients who did not follow doctors’advice were inappropriate,as they did not conform to the principle of treatment.The present study showed that surgical correction seemed to be an objectively effective option in the management of patients in the stable chronic phase of PD.Low patient satisfaction might be related to patients’lack of correct understanding of the disease and its treatment strategy as well as unrealistic expectations. | Da-Chao Zheng Jie-Wen Bao Jian-Hua Guo Min-Kai Xie Wen Ji Li Zhong Wang | 2021 | Asian Journal of Andrology2021,23,5: | 0 |
| 8 | Use of a lyophilized bovine pericardium graft to repair tunical defect in patients with Peyronie's disease: experience in a clinical setting显示文摘许多不同材料在为 Peyronies 疾病(PD ) 的外科期间为 grafting 是可得到的。为了学习结果,把牛的心包接枝与 lyophilized 的使用联系了(仙子警卫 ?) 到在有 PD 的病人,的修理 tunical 缺点,有停用阴茎弯曲的 43 个病人的描述的学习被执行。弯曲用一个标准化过程在干预前后被测量。外科的技术是匾切除, tunical 缺点的 grafting 由一位单身的外科医生执行了。lyophilized 牛的心包补丁被用于 grafting。我们在阴茎弯曲和长度测量了变化,没有进一步的药理学,执行成功的性交的能力或外科的治疗,和对治疗的满足。后续数据为 41 个病人的一个总数是可得到的。中部的年龄是 50 年(IQR 48-52 ) ;吝啬的后续时间是 14 ?? 鎻郥蚺 ? ? 挠瑹浯瑥祲 ? 胣? 吗?? | Javier Romero Otero Borja Garcia Gomez Jose Medina Polo Carlos Pascual Mateoe Silvia Garcia Barreras Eduard Garcia Cruz Javier de la Riva de la Vifia Alfredo Rodriguez Antolin | 2017 | Asian Journal of Andrology2017,19,3: | 0 |
| 9 | New insights into the pathogenesis of Peyronie’s disease:A narrative review显示文摘Peyronie’s disease(PD)is a benign,progressive fibrotic disorder characterized by scar or plaques within the tunica albuginea(TA)of the penis.This study provides new insights into the pathogenesis of PD based on data from different studies regarding the roles of cytokines,cell signaling pathways,biochemical mechanisms,genetic factors responsible for fibrogenesis.A growing body of literature has shown that PD is a chronically impaired,localized,wound healing process within the TA and the Smith space.It is caused by the influence of different pathological stimuli,most often the effects of mechanical stress during sexual intercourse in genetically sensitive individuals with unusual anatomical TA features,imbalanced matrix metalloproteinase/tissue inhibitor of metalloproteinase(MMP/TIMP),and suppressed antioxidant systems during chronic inflammation.Other intracellular signal cascades are activated during fibrosis along with low expression levels of their negative regulators and transforming growth factor-β1 signaling.The development of multikinase agents with minimal side effects that can block several signal cell pathways would significantly improve fibrosis in PD tissues by acting on common downstream mediators. | Denis V.Krakhotkin Volodymyr A.Chernylovskyi Alexandre Mottrie Francesco Greco Ruslan A.Bugaev | 2020 | Chronic Diseases and Translational Medicine2020,6,3: | 0 |