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| 1 | 奥美拉唑联合铝碳酸镁治疗胃溃疡合并胃出血的临床效果显示文摘目的探讨奥美拉唑联合铝碳酸镁治疗胃溃疡合并胃出血的临床效果。方法回顾性分析本院2010年1月—2013年6月收住消化内科治疗的胃溃疡合并胃出血患者86例,随机分为两组,每组43例,分别予以奥美拉唑联合铝碳酸镁(观察组)和单用奥美拉唑(对照组)治疗,比较两组患者治疗后临床疗效、症状评分以及不良反应情况。结果观察组治疗总有效率95.4%高于对照组76.8%;治疗后症状评分低于对照组,两组比较差异均有统计学意义(P<0.05)。观察组不良反应发生率高于对照组,但差异无统计学意义(P>0.05)。结论奥美拉唑联合铝碳酸镁治疗胃溃疡合并胃出血临床疗效好,症状评分低,不良反应无特殊性增高,适合临床广泛应用。 | 侯杰 | 2014 | 临床合理用药杂志2014，7，9： | 32 |
| 2 | Predictors of double balloon endoscopy outcomes in the evaluation of gastrointestinal bleeding显示文摘AIM:To identify patients' characteristics associated with double balloon endoscopy(DBE)outcomes in investigation of obscure gastrointestinal bleeding(OGIB).METHODS:Retrospective study performed at an academic tertiary referral center.Evaluated endpoints were clinical factors associated with no diagnostic yield or non-therapeutic intervention of DBE performed for OGIB evaluation.RESULTS:We included fifty-five DBE between August 2010 and April 2012.The mean age of the sample was 67 with 32 males(58.2%).Twenty-four DBE had no diagnostic yield and 30 DBE did not require therapy.Non-diagnostic yield was associated with performing two or more DBE studies in one day [odds ratio(OR):13.72,P=0.008],absence of blood transfusions within a year of the DBE(OR:7.16,P=0.03)and absence of ulcers or arteriovenous malformations(AVMs)on prior esophagogastroduodenoscopy(EGD)or colonoscopy(OR:19.30,P=0.033).Non-therapeutic DBE was associated with performing two or more DBE per day(OR:18.579,P=0.007),gastrointestinal bleeding episode within a week of the DBE(OR:11.48,P=0.003),fewer blood transfusion requirements prior to DBE(OR:4.55,P=0.036)and absence of ulcers or AVMs on prior EGD or colonoscopy(OR:8.47,P=0.027).CONCLUSION:Predictors of DBE yield and therapeutic intervention on DBE include blood transfusion requirements,previous endoscopic findings and possibly endoscopist fatigue. | Hisham Hussan Nicholas R Crews Caroline M Geremakis Soubhi Bahna Jennifer L LaBundy Christine Hachem | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，6： | 3 |
| 3 | Small intestinal vascular malformation bleeding:A case report with imaging findings显示文摘The small intestine is approximately 5-6 m long and occupies a large area in the abdominal cavity. These factors preclude the use of ordinary endoscopy and X-ray to thoroughly examine the small intestine for bleeding of vascular malformations. Thus,the diagnosis of intestinal bleeding is very difficult. A 47-year-old man presented at the hospital 5 mo ago with dark stool. Several angiomas were detected by oral approach enteroscopy,but no active bleeding was observed. Additionally,no lesions were detected by anal approach enteroscopy;however,gastrointestinal tract bleeding still occurred for an unknown reason. We performed an abdominal vascular enhanced computed tomography examination and detected ileal vascular malformations. Ileum angioma and vascular malformation were detected by a laparoscopic approach,and segmental resection was performed for both lesions,which were confirmed by pathological diagnosis. This report systemically emphasizes the imaging findings of small intestinal vascular malformation bleeding. | Jun Cui Liu-Ye Huang Shu-Juan Lin Long-Zhi Yi Cheng-Rong Wu Bo Zhang | 2014 | World Journal of Gastroenterology2014，20，38： | 2 |
| 4 | 疑似小肠出血的处理原则显示文摘消化道出血为小肠疾病的常见表现之一。上、下消化道内镜检查均未发现出血原因的患者则考虑为疑似小肠出血。随着胶囊内镜、器械辅助式小肠镜、影像学检查的问世和发展,大部分疑似小肠出血患者可借助这些检查手段明确出血原因,并根据检查结果进行相应处理。如何选择合适的检查方法、检查时机和治疗方案是疑似小肠出血处理的关键。本文就疑似小肠出血患者的处理原则作一概述。 | 汤铭昱 戈之铮 | 2019 | 胃肠病学2019，24，12： | 0 |
| 5 | 中西医结合治疗难治性海德综合征1例显示文摘海德综合征跨学科的临床表现,及其“三联征”(主动脉瓣狭窄、顽固性消化道出血、相对应的肠道血管发育不良或获得性血管性血友病综合征)的相关诊查手段的有限准确性,使得该病易被漏诊误诊。其根治疗法——主动脉瓣置换术常因临床上出血扩容与心衰利尿、手术抗凝与输血止血的治疗矛盾而被延误。本文报道1例顽固性消化道出血的海德综合征病例,该患者初期接受肠段切除术后仍反复发生消化道出血,在接受清热活血汤等中药治疗及经皮主动脉瓣置入术(TAVI)后,随访2年未复发缺血与出血事件且心功能得到较大改善。清热活血、益气利水中药与TAVI联合可为高危、难治性海德综合征患者的治疗提供新思路。 | 李睿 章洁淳 纪树亮 卿立金 吴伟 | 2022 | 中国中医急症2022，31，12： | 0 |
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