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1Sessile serrated adenoma/polyps: Where are we at in 2016?显示文摘It is currently known that colorectal cancers(CRC) arise from 3 different pathways: the adenoma to carcinoma chromosomal instability pathway(50%-70%); the mutator 'Lynch syndrome' route(3%-5%); and the serrated pathway(30%-35%). The World Health Organization has classified serrated polyps into three types of lesions: hyperplastic polyps(HP),sessile serrated adenomas/polyps(SSA/P) and traditional serrated adenomas(TSA),the latter two strongly associated with development of CRCs. HPs do not cause cancer and TSAs are rare. SSA/P appear to be the responsible precursor lesion for the development of cancers through the serrated pathway. Both HPs and SSA/Ps appear morphologically similar. SSA/P are difficult to detect. The margins are normally inconspicuous. En bloc resection of these polyps can hence be troublesome. A careful examination of borders,submucosal injection of a dye solution(for larger lesions) and resection of a rim of normal tissue around the lesion may ensure total eradication of these lesions.Rajvinder Singh Leonardo Zorrón Cheng Tao Pu Doreen Koay Alastair Burt 2016World Journal of Gastroenterology2016,22,34:13
2放大内镜窄带成像技术在结直肠早癌诊断中的应用进展显示文摘放大内镜窄带成像技术(magnifying endoscopy with narrow-banding imaging,ME-NBI)是一种新型的内镜诊断技术,相比于传统的几种内镜检查,在诊断消化道早癌有其自身的特点。本文对各种结直肠病变的NBI分型进行介绍,同时回顾了近几年关于结直肠早癌ME-NBI诊断的临床研究,阐述这一新兴技术应用于结直肠早癌诊断的优越性。蔡世伦 钟芸诗 2014中华结直肠疾病电子杂志2014,3,6:9
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