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| 1 | Clinical features of hepatic angiomyolipoma显示文摘BACKGROUND:Hepatic angiomyolipoma(HAML)is a rare hepatic mesenchymal tumor.This study was designed to explore its clinical features. METHODS:Clinical data from 26 patients who had been pathologically confirmed with HAML and had received surgical resection at our hospital were analyzed retrospectively. RESULTS:HAML was seen more frequently in females(18/26) in this series,and most of the patients presented no significant symptoms except for one who had a spontaneous rupture hemorrhage.Serum alpha-fetoprotein(AFP),carbohydrate antigen 19-9(CA19-9)and carcinoembryonic antigen(CEA) were negative in all patients.Imaging presentations were diverse.Pre-operative diagnosis was made in only 3 patients Pathological study showed that the tumor was composed of adipose tissue,smooth muscle and blood vessels in different proportions.One patient showed hepatic vessel invasion HMB-45 immunohistochemical staining was positive in all tumors.All patients underwent surgical resection without significant complications.Except for one patient who died 14 months after operation because of recurrent disease,no tumor recurrence was observed in the remaining 25 patients during a 2-3 years follow-up. CONCLUSIONS:Pre-operative diagnosis of HAML is difficult.There are potential risks of spontaneous rupture and malignant transformation.Surgical resection is the treatment of choice for HAML. | Zhou, Yan-Ming Li, Bin Xu, Feng Wang, Bin Li, Dian-Qi Zhang, Xiao-Feng Liu, Peng Yang, Jia-Mei | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，3： | 9 |
| 2 | Juxta-caval hepatic angiomyolipoma masquerading as hepatocellular carcinoma显示文摘ABSTRACT: Hepatic angiomyolipoma is an uncommon primary benign epithelial liver neoplasm. Mostpatients with angiomyolipomas are middle-aged women who commonly present with epigastric fullness orpain. Angiomyolipomas are tumors consisting of three tissue types: blood vessels, smooth muscle, and fat.Hepatic angiomyolipomas may be difficult to differentiate from other liver neoplasms by noninvasiveimaging. We report a 58-year-old asymptomatic woman with a mass in the right lobe of the liver, foundincidentally on routine abdominal sonography. Preoperative radiographic evaluation revealed a 6.5-cmhypervascular lesion abutting the inferior vena cava. Preoperative histologic study demonstrated anepithelial neoplasm suspicious for hepatocellular carcinoma. Metastatic workup was negative. Atresection, the tumor was found to be an angiomyolipoma composed of lipoid, vascular and smooth musclecells. Further staining was positive for HMB-45. Resection margins were negative. The woman had anuneventful recovery and was discharged on postoperative day seven. She currently remains well severalmonths after her right hepatectomy. | Alan M Hawxby Michael Torbenson Elliot Fishman Leo Lawler Luis M Arrazola Andrew S Klein | 2003 | Hepatobiliary & Pancreatic Diseases International2003，2，4： | 0 |
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