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| 1 | Relationship between vitamin D deficiency and cardiovascular disease显示文摘Epidemiological studies have found that low 25-hydroxyvitamin D levels may be associated with coronary risk factors and adverse cardiovascular outcomes.Additionally,vitamin D deficiency causes an increase in parathyroid hormone,which increases insulin resistance and is associated with diabetes,hypertension,inflammation,and increased cardiovascular risk.In this review,we analyze the association between vitamin D supplementation and the reduction in cardiovascular disease.The role of vitamin D deficiency in cardiovascular morbidity and mortality is still controversial,and larger scale,randomized placebo controlled trials are needed to investigate whether oral vitamin D supplementation can reduce cardiovascular risk.Given the low cost,safety,and demonstrated benefit of higher 25-hydroxyvitamin D levels,vitamin D supplementation should become a public health priority for combating common and costly chronic cardiovascular diseases. | Yan-Chiou Ku Mu-En Liu Chang-Sheng Ku Ta-Yuan Liu Shoa-Lin Lin | 2013 | World Journal of Cardiology2013，5，9： | 8 |
| 2 | 维生素D与心血管系统疾病显示文摘维生素D(Vitamin D)是一种脂溶性甾体激素前体,具抗佝偻病作用,故又称抗佝偻病维生素,绝大多数的细胞存在维生素D受体(VDR),传统观点认为维生素D通过VDR介导调节钙磷代谢,促进细胞生长和分化,近年来研究表明维生素D对冠状动脉粥样硬化性心脏病、心力衰竭、高血压、周围血管病等心血管系统疾病发挥着重要影响,却没有足够的证据来证明维生素D缺乏是心血管系统疾病的一个独立的危险因素〔1〕。 | 肖甜甜 左嵩 周雯倩 郝守艳 秦聪 郑杨 | 2014 | 中国老年学杂志2014，34，6： | 2 |
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