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| 1 | Comparative analysis of open and laparoscopic colectomy for malignancy in a developing country显示文摘AIM: To compare the short-term, including oncologic, outcomes of open vs laparoscopic colectomy for cancer in a developing country. METHODS: The records of patients who underwent elective open and laparoscopic colectomies for cancer at the University Hospital of the West Indies between January 2005 and December 2010 were retrospectively reviewed. Demographic(age, gender, Charlson comorbidity index score), peri-operative, post-operative and oncologic data were collected for each patient. Specific oncologic variables included lymph node yield, pathologic stage, grade, proximal, distal and circumferential margin involvement. Fisher's exact, Mann-Whitney, and binary logistic regression tests were used for analysis. Significance level was set atP < 0.05. RESULTS: There were 87 cases for open colectomy(OC) and 17 cases for laparoscopic colectomy(LC). Demographics did not significantly differ between OC and LC groups. Intra-operative blood loss and postoperative analgesic requirements did not significantly differ between groups. There was a trend towards longer operating times in OC group and shorter hospital stay in the LC group. Lymph node yield(14 vs 14, P = 0.619), proximal(10 cm vs 7 cm, P = 0.353) and distal(8 cm vs 8 cm, P = 0.57) resection margin distance and circumferential margin involvement(9 vs 0, P = 0.348) did not significantly differ between groups. Thirty-day morbidity was equivalent between groups(22 vs 6, P = 0.774). There were 6 deaths within 30 d of initial procedure, all in the OC group(6.9%). CONCLUSION: Laparoscopic colectomy in a developing country is oncologically safe and represents a option for colonic malignancies in these regions. Such data encourage the continued laparoscopic development. | Pierre-Anthony Leake Kristen Pitzul Patrick O Roberts Joseph M Plummer | 2013 | World Journal of Gastrointestinal Surgery2013，5，11： | 8 |
| 2 | 老年直肠癌患者行腹腔镜与开腹根治术的临床对比显示文摘目的探讨腹腔镜与开腹直肠癌根治术治疗老年人直肠癌的疗效。方法收集70岁以上直肠癌患者132例,腔镜组(LR组)54例,开腹组(OR组)78例,两组进行比较。结果两组均无死亡病例。术中出血量、排气时间、进食时间、镇痛药使用时间、SIRS持续时间及术后住院时间LR组明显低于OR组(P<0.01),LR组留置尿管时间及切口感染少于OR组(P<0.05)。手术时间、淋巴结清扫数目、吻合口瘘、肠梗阻、尿潴留均无统计学意义(P>0.05)。结论腹腔镜直肠癌根治术治疗老年直肠癌是安全有效的,与开腹手术对比,老年人获益是明显的。 | 殷红专 郝荣 闫兆鹏 孙威 尹剑桥 刘宝林 苏琪 | 2014 | 中国老年学杂志2014，34，6： | 2 |
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