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1TRIZ理论的传播及对我国的影响显示文摘党的十七大报告把'提高自主创新能力,建设创新型国家'作为国家发展战略的核心和提高综合国力的关键,摆在'促进国民经济又好又快发展'部分的首要位置。这就为我们今后的TRIZ理论引进、推广与转化等系统化工作提出了任务、指明了方向。运用实证分析、比较分析的方法,释明TRIZ理论传播与技术创新对我国的影响和作用。张炜达 肖周录 2011生产力研究2011,,11:12
2Molecular Comparisons of Marek's disease virus strains of different pathotypes for their gI,gE,pp38 and meq genes显示文摘Five to ten serotyqe I Marek’s disease virus (MDV1) strains of different pathotypes were compared for their DNA sequences of gI, gE, pp38 and meq genes. The reference strains were vMDV GA and JM, vvMDV RB1B and Md11(p16), vv+MDV strains 648A and 584A,vaccine strain CVI988/Rispens; Chinese strains were: v MDV strain N, vvMDV strain G2, vaccine strain 814. Only random aa changes were found in 12 positions within gE of 497 aa among 10 analyzed strains and in 10 positions within gI of 355 aa among 5 strains. There was no relationship found between virus pathotypes and aa changes of both glycoproteins. The aa changes happened in 14 positions within meq of 339 aa among 5 compared strains. But a proline deletion at aa #194 in a proline-rich domain of meq were shared by two vaccine strains CVI988/Rispens and 814, the latter was a non-pathogenic vaccine strain of serotype 1 isolated in 1983 in China. In another hand, vv+MDV strains 648A demonstrated 5 unique aa changes and 4 of them also located in the proline-rich region. The pp38 was very conservative among sequenced 10 strains, there were only two positions at #107 and #109 with aa altered in its 290 aa. All tested MDV1 strains had glutamine at #107, instead, only vaccine CVI988 had arginine at the position and lost its epitope reactive with Mab H19, to which all other tested MDV1 strains were positive. However, CVI988 and vMDV GA shared a Mab T65-recognized epitope when there was glycine at aa#109. It was glutamic acid at aa#109 in all other MDV1 strains which were not reactive with Mab T65. It seems like that there is some relationship between pathotypes and sequences of pp38 and meq, but more strains need to be compared.CUIZhi-zhong WEIPin DINGJia-bo ZHUSu-juan 2004山东农业大学学报(自然科学版)2004,35,1:0
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