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| 1 | Epithelioid angiomyolipoma of the liver:Cross-sectional imaging findings of 10 immunohistochemically-verified cases显示文摘AIM:To retrospectively evaluate the computed tomography(CT)/magnetic resonance imaging(MRI) imaging features of epithelioid angiomyolipoma of the liver(Epi-HAML),with pathology as a reference. METHODS:The CT/MRI findings(number,diameter, lobar location,and appearance of lesions)in a series of 10 patients with 12 pathologically proven epithelioid angiomyolipomas of the liver were retrospectively analyzed.The imaging features,including attenuation/ signal intensity characteristics,presence of fat, hypervascular,outer rim,and vessels within lesion, were evaluated and compared with that of non-Epi-HAML in 11 patients(13 lesions).The Fisher exact test was used to compare difference in probability of imaging features between the two types. RESULTS:For 21 patients,CT images of 15 patients and MR images of six patients were available.No patient underwent two examinations.For the 15 patients with a CT scan,all HAML lesions in the two groups(10 Epi-HAML and seven non-Epi-HAML) manifested as hypoattenuation.For the six patients with MRI,all lesions(two Epi-HAML and six non-Epi- HAML)were hypointense on T1WI(fat suppression)and hyperintense on T2WI.There were 10 non-Epi-HAML, but only two Epi-HAML lesions showed the presence offat,which significantly different between the two types (P=0.005).On the dynamic contrast enhancement (DCE)imaging,eight Epi-HAML,and 13 non-Epi lesions manifested as hypervascular.Punctate or curved vessels were displayed in 10 Epi-HAML as well as in nine non-Epi lesions and outer rim enhancement could be found with eight Epi-HAML as well as six non-Epi lesions. CONCLUSION:Little or no presence of adipose tissue was found to be an imaging feature of Epi-HAML,compared with the non-Epi type.In addition, hypervascularity with opacification of central punctiform or filiform vessels on DCE would be a characteristic enhancement pattern for Epi-HAML. | Peng-Ju Xu Yan Shan Fu-Hua Yan Yuan Ji Ying Ding Mei-Lin Zhou | 2009 | World Journal of Gastroenterology2009，15，36： | 24 |
| 2 | 超声造影和声辐射力脉冲技术在肾良恶性肿瘤鉴别诊断中的价值比较显示文摘目的探讨超声造影和声辐射力脉冲技术在鉴别诊断肾实质良恶性病灶中的应用价值。方法对67例疑似肾肿瘤患者进行超声造影(CEUS)和声辐射力脉冲(ARFI)技术检查,所有检查结果均经手术后病理证实或随访观察证实,采用双盲法分析两种超声技术对肾脏良恶性肿瘤的诊断价值。结果CEUS诊断肾良、恶性肿瘤的敏感度、特异性、准确率分别为89.80%、88.89%、89.55%;ARFI技术诊断的敏感度、特异性、准确率分别为81.63%、83.33%、82.09%;两者的诊断效能(敏感度、特异性、准确率)差异无统计学意义(均P>0.05)。结论 CEUS与ARFI技术在诊断肾脏肿瘤的良恶性方面,具有相似的敏感度和准确率,两者对肾脏肿瘤的诊断可起到互补作用,为临床正确诊治疾病提供参考。 | 吴正华 周爱云 张诚 肖帆 | 2016 | 肿瘤防治研究2016，43，12： | 7 |
| 3 | 声辐射力脉冲技术在肾肿瘤诊断中的应用价值显示文摘目的:探讨声辐射力脉冲(acoustic radiation force impulse,ARFI)技术在肾肿瘤诊断中的应用价值。方法:对110例患者共110个肾肿瘤行声触诊组织成像(virtual touch tissue imaging,VTI)及声触诊组织量化(virtual touch tissue quantification,VTQ)检查,获取其VTI图像及肾肿瘤、患侧肾皮质、对侧肾皮质的剪切波速度(shear wave velocity,SWV)值,全部病例均经手术后病理证实。结果:病理证实良性肾肿瘤20个(血管平滑肌脂肪瘤18个,嗜酸细胞腺瘤2个),恶性肿瘤90个(透明细胞癌72个,嫌色细胞癌8个,乳头状癌6个,囊性肾癌4个)。VTI诊断肾恶性肿瘤的敏感度、特异性、阳性预测值、阴性预测值、准确率、Youden指数及ROC曲线下面积分别为71.11%(64/90)、70.00%(14/20)、91.43%(64/70)、35.00%(14/40)、70.91%(78/110)、41.11%、0.706。VTQ诊断肾恶性肿瘤的敏感度、特异性、Youden指数、ROC曲线下面积及最佳截断点值分别为66.70%、90.00%、56.70%、0.748、2.44 m/s。良性肿瘤与同侧肾皮质之间(P=0.000)、恶性肿瘤与同侧肾皮质之间(P=0.000)、良性肿瘤与恶性肿瘤之间(P=0.013)以及血管平滑肌脂肪瘤与透明细胞癌之间(P=0.022)SWV值差异有统计学意义,良性肿瘤与恶性肿瘤之间(P=0.010)以及血管平滑肌脂肪瘤与透明细胞癌之间(P=0.017)SWV比值差异有统计学意义。结论:ARFI技术可以提供肾肿瘤的VTI定性及VTQ定量的弹性信息,诊断准确度均达到中等,在肾肿瘤的诊断中有一定临床应用价值。 | 赵景 陈莉 周翠翠 王婧玲 谌芳群 | 2014 | 实用医学杂志2014，30，15： | 4 |
| 4 | 肝血管平滑肌脂肪瘤的诊断和治疗显示文摘目的:探讨肝血管平滑肌脂肪瘤(hepatic angiomyolipoma,HAML)的临床及影像学表现、病理特点、鉴别诊断、治疗及预后.方法:报道H A M L临床病例1例,检索1987-2014年国内文献,取其中资料相对完整的540例,对541例HAML临床表现、实验室检查、影像学检查、手术方式、病理学检查和随访资料进行临床分析.结果:541例HAML患者以女性多见,无明显症状361例(66.7%),实验室检查多无异常,影像学诊断阳性率:B超1.4%(4/283)、CT 37.4%(131/350)、MRI 16.17%(38/235),且CT诊断价值较高(CT vs MRI:χ2=11.321,P=0.001;CT vs B超:χ2=42.105,P=0.000),病理诊断免疫组织化学指标肿瘤细胞表达黑色素瘤抗体-45(human melanoma black-45,HMB-45)表达阳性率97.8%(357/365)、平滑肌激动蛋白(smooth muscle actin,SMA)阳性率93.7%(207/221)、Vimentin阳性率62.5%(30/48)、CD-34阳性率40.5%(51/126)、CD-117阳性率39.0%(48/123),外科手术治疗521例(96.3%),术后良性预后98.7%(231/234).结论:HAML缺乏特征性临床表现,影像学表现多样,术前诊断正确率低、误诊率高,有待病理及免疫组织化学确诊,首选手术治疗,预后良好. | 李永杰 刘文艺 刘莉 周耿 方孟园 | 2014 | 世界华人消化杂志2014，22，20： | 2 |
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