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| 1 | Calcium phosphate cements for bone engineering and their biological properties显示文摘Calcium phosphate cements(CPCs) are frequently used to repair bone defects. Since their discovery in the 1980 s, extensive research has been conducted to improve their properties, and emerging evidence supports their increased application in bone tissue engineering. Much effort has been made to enhance the biological performance of CPCs, including their biocompatibility, osteoconductivity, osteoinductivity, biodegradability,bioactivity, and interactions with cells. This review article focuses on the major recent developments in CPCs,including 3 D printing, injectability, stem cell delivery, growth factor and drug delivery, and prevascularization of CPC scaffolds via co-culture and tri-culture techniques to enhance angiogenesis and osteogenesis. | Hockin HK Xu Ping Wang Lin Wang Chongyun Bao Qianming Chen Michael D Weir Laurence C Chow Liang Zhao Xuedong Zhou Mark A Reynolds | 2017 | Bone Research2017，5，4： | 14 |
| 2 | Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction显示文摘Zika 病毒(ZIKV ) 的最近的爆发为治疗学加亮迫切需要。朊酶建筑群 NS2B-NS3 在 flaviviral polyprotein 处理期间起必要作用,并且因此代表一个吸引人的药目标。这里,我们开发了裂口酶识别直接指向 flavivirus NS2B-NS3 相互作用的 orthosteric 禁止者的基于互补的高产量的屏蔽试金。由屏蔽一个总数 2 816 同意了并且 investigational 药,我们识别了三个有势力候选人, temoporfin, niclosamide,和 nitazoxanide,,有 nanomolar 力量的 flavivirus NS2B-NS3 相互作用禁止者。显著地,在老鼠的在人的胎盘、神经的祖先房间的大多数有势力化合物, temoporfin,不是仅仅禁止的 ZIKV 复制,而且阻止的导致 ZIKV 的 viremia 和死亡当模特儿。结构的停靠建议 temoporfin 潜在地绑保持批评 NS2B 残余的 NS3 衣袋,因此禁止以一种非竞争的方式处理的 flaviviral polyprotein。当这些药已经在 USA 或另外的国家在另外的指示任何一个为临床的使用被同意了,他们由 ZIKV 和另外的 flaviviruses 为感染的管理代表有希望、容易开发的治疗。 | Zhong Li Matthew Brecher Yong-Qiang Deng Jing Zhang Srilatha Sakamuru Binbin Liu Ruili Huang Cheri A Koetzner Christina A Allen Susan A Jones Haiying Chen Na-Na Zhang Min Tian Fengshan Gao Qishan Lin Nilesh Banavali Jia Zhou Nathan Boles Menghang Xia Laura D Kramer Cheng-Feng Qin Hongmin Li | 2017 | Cell Research2017，27，8： | 11 |
| 3 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009，7，4： | 3 |
| 4 | Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy显示文摘 | Sinha Rohit Anthony You Seo-Hee Zhou Jin Siddique Mobin M Bay Boon-Huat Zhu Xuguang Privalsky Martin L Cheng Sheue-Yann Stevens Robert D Summers Scott A Newgard Christopher B Lazar Mitchell A Yen Paul M | 2012 | EN2012，，7： | 2 |
| 5 | A study of the electrochemical formation of Cu (Ⅰ)-BTA films on coppor electrodes and the mechanism of copper corrosion inhibition in aqueous chloride/benzotriazole solutions显示文摘 | MODESTOV A D ZHOU G D WU Y P | 1994 | Corrosion Science1994，36，11： | 2 |
| 6 | The transmembrane protein semaphorin 6A repels embryonic sympathetic axons显示文摘 | Xu X M Fisher D A Zhou L | 2000 | J Neurosci2000，20，： | 1 |
| 7 | Identification of genes differentially regulated by interferon alpha,beta,or gamma using oligonucleotide arrays显示文摘 | Der S D Zhou A Williams B R | 1998 | Proc Natl Acad Sci USA1998，95，15： | 1 |
| 8 | A Wavelet Transform Method to Merge Landsat TM and SPOT Panchromatic Data显示文摘 | ZHOU J CIVICO D L SILANDER J A | 1998 | International Journal of Remote Sensing1998，19，： | 1 |
| 9 | A wavelet transform method to merge landsat and SPOT panchromatic data显示文摘 | Zhou J Civco D L Silander J A | 1998 | Int J Remote Sensing1998，19，4： | 1 |
| 10 | Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells 显示文摘 | Meng A Wang Y Van Zant G Zhou D | 2003 | Cancer Res2003，63，17： | 1 |
| 11 | Increased neureglobin levels in the cerebral cortex and serum after ischemia-reperfusian insuits显示文摘 | Shang A Zhou D Wang L Gao Y | 2006 | Brain Res2006，1078，1： | 1 |
| 12 | Formation and reduction of nitric oxide in fixed-bed combustion of straw显示文摘 | Zhou H Jensen A D Glarborg P | 2006 | Fuel2006，85，56： | 1 |
| 13 | SHRIMP U - Pb zircon geochronological and geochemical evidence for Neoproterozoic arc-magmatism along the western margin of the Yangtze Block, South China 显示文摘 | Zhou M F Yan D P Kennedy A K | 2002 | Earth and Planetary Science Letters2002，196，1： | 1 |
| 14 | Multidrug resistance gene expression in acute myeloid leukemia: major prognosis significance forin viva clrug resistance to induction treatmen 显示文摘 | Hunauh M Zhou D Delmer A | 1997 | T Ann-Hemato1997，74，2： | 1 |
| 15 | Corrosion behavior of friction stir welded AA7108-T79 aluminium alloy显示文摘 | Wadeson D A Zhou X | 2006 | Corrosion Science2006，，48： | 1 |
| 16 | Using the amide proton signals of intracellular proteins and peptides to detect ph effects in MRI显示文摘 | Zhou J Payen J F Wilson D A | 2003 | Nat Med2003，9，： | 1 |
| 17 | Sequential Evaporation of Bi-Te Thin Films with Controllable Composition and Their Thermoelectric Transport Properties显示文摘 | ZHOU A J FENG L D CUI H G | 2013 | Journal of Electronic Materials2013，42，7： | 1 |
| 18 | Protocatechuic aldehyde suppresses TNF-alpha-induced ICAM and VCAM-1 expression in human umbilical vein endothelial cells显示文摘 | Zhou Z Liu Y Miao A D | 2005 | Eur J Pharmacol2005，185，12： | 1 |
| 19 | Extended transformed stress space for geomaterials and its application显示文摘 | YAO Y P ZHOU A N LU D C | 2007 | Journal of Engineering Mechanics ASCE2007，133，10： | 1 |
| 20 | Shrimp zircon geochronological and geochemical evidence for Neo - Proterozoic arc - related magmatism along the western of the Yangtze Block, South China 显示文摘 | Zhou M F Yah D P Kennedy A K Li Q I and Ding J | 2002 | Earth Planet Sci Lett2002，196，： | 1 |
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