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| 1 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 2 | 美国重症肌无力基金会关于重症肌无力临床试验的建议显示文摘由美国重症肌无力基金会(MGFA)的医学科学建议委员会(MSAB)组成工作组,于2010年在美国和2011年在意大利召开专家共识会议讨论重症肌无力(MG)临床试验的问题,与会代表包括来自美国和欧洲的神经科医生、统计学家、企业界代表、MG患者以及MGFA和欧洲重症肌无力协会的平民代表。 | Benatar M Sanders DB Burns TM Cutter GR Guptill JT Baggi F Kaminski HJ Mantegazza R Meriggioli MN Quan J Wolfe GI 李海峰(摘译) 高翔(摘译) | 2013 | 中国神经免疫学和神经病学杂志2013，20，1： | 2 |
| 3 | Wave scattering by a canyon of arbitrary shape in a layered half space显示文摘 | Vogt R F Wolf J P Bachmann H | 1988 | Earthquake Engineering and Structural Dynamics1988，16，： | 1 |
| 4 | Aprospective, multicentre, open - label study of aripiprazole in the management of patients with schizophrenia in psychiatric pratice in Europe :Broad Effeetiveness Trial with Aripiprazole in Europe ( EU - BETA) 显示文摘 | Wolf J Janssem F Lubin H | 2007 | Curr Med Res Opin2007，23，： | 1 |
| 5 | CO2 enhanced coalbed methane production in the Netherlands显示文摘 | Hamelinck C N Faaij A P C Turkenburg W C F van Bergen Pagnier H J M Barzandji O H M Wolf K -H A A Ruijg G J | 2002 | Energy2002，27，7： | 1 |
| 6 | Clinical pharma- cokinetics of erlotinib in patients with solid tumors and exposure-safety relationship in patients with non-small cell lung cancer 显示文摘 | LU J F EPPLER S M WOLF J | 2006 | Clin Pharmacol Ther2006，374，80： | 1 |
| 7 | The effects of irrigation on out- comes in cases of perforated appendicitis in children显示文摘 | Hartwich J E Carter R F Wolfe L | 2013 | J Surg Res2013，180，2： | 1 |
| 8 | Substantial superiority of semiflexed (MTP) views in knee osteoarthritis: a comparative radiographic study, without fluoroscopy, of standing extended, semiflexed ( MTP), and schuss views 显示文摘 | Buckland - Wright JC Wolfe F Ward R J | 1999 | J Rheumatol1999，12，： | 1 |
| 9 | Computer-assisted and conventional total knee replacement: a comparative, prospective, randomised study with radiological and CT evaluation 显示文摘 | Lutzner J Krummenauer F Wolf C | 2008 | J Bone Ioint Surg Br2008，90，8： | 1 |
| 10 | Conservation of methylation reprogramming in mammalian development:aberrant reprogramming in cloned embryos显示文摘 | Dean W Santos F Stojkovic M Zakhartchenko V Walter J Wolf E Reik W | 2001 | Proceedings of the National Academy of Sciences2001，98，13： | 1 |
| 11 | Is the reaction catalyzed by 3-hydroxy-3-methylglutaryl coenzyme A reductase a rate-limiting step for isoprenoid biosynthesis in plants?显示文摘 | Chappell J Wolf F Proulx J | 1995 | Plant physiol1995，109，： | 1 |
| 12 | Infertility associated with Eperythrozoon wenyonii infection in a bull 显示文摘 | Montes A J Wolfe D F Welles E G | 1994 | JAVMA1994，204，2： | 1 |
| 13 | Hematologic and semen quality changes in bulls with experimental eperythrozoon infection显示文摘 | WELLES E G TYLER J W WOLFE D F | 1995 | Teriogenology1995，43，： | 1 |
| 14 | Achieving sub-pixel geolocation accuracy in support of MODIS land science显示文摘 | Wolfe R E Nishihama M Fleig A J Kuyper J A Roy D P Storey J C and Patt F S | | 0，，1： | 1 |
| 15 | Kinetics, FTIR, and controlled atmosphere EXAFS study of the effect of chlorine on ptsupported catalysts during oxidation reactions显示文摘 | GRACIA F J MILLER J T KROPF A J WOLF E E | 2002 | J Catal2002，209，2： | 1 |
| 16 | Eperythro-zoon infection in young bulls with scrotal and hindlimb edema,a herd outbreak显示文摘 | WELLES E G TYLER J W WOLFE D F | 1995 | Teriogenology1995，43，： | 1 |
| 17 | Disposition of ronidazole by swine 1 radiocarbon content of tissues 显示文摘 | WOLF F J BAYLIS F P SMITH G E | 1983 | J Agric Food Chem1983，31，： | 1 |
| 18 | Rigid-rod polymers:1, Synthesis and thermal properties of para-aromatic polymers with 2,6-benzobisthiazole unites in the main chain显示文摘 | Wolfe J F Arnold F E | 1981 | Macromolecules1981，14，4： | 1 |
| 19 | Is the reaction cat- alyzed by 3-hydroxy-3-methylglutaryl coenzyme A re- ductase a rate-limiting step for isoprenoid biosynthe- sis in plants 显示文摘 | Chappell J Wolf F Proulx J | 1995 | Plant Physioly1995，109，4： | 1 |
| 20 | Percutaneous radiofrequency coagulation of osteoid osteoma compared with operative treatment显示文摘 | Rosenthal DI Hornicek F J Wolfe MW | 1998 | J Bone Joint Surg Am1998，80，： | 1 |
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