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| 1 | Effect of propranolol on the splanchnic and peripheral renin angiotensin system in cirrhotic patients显示文摘AIM:To evaluate the effect of β-blockade on angiotensins in the splanchnic and peripheral circulation of cirrhotic patients and also to compare hemodynamic parameters during liver transplantation according to propranolol pre-treatment or not. METHODS:Patients were allocated into two groups:outpatients with advanced liver disease(LD) and during liver transplantation(LT). Both groups were subdivided according to treatment with propranolol or not. Plasma was collected through peripheral venipuncture to determine plasma renin activity(PRA),Angiotensin(Ang) Ⅰ,Ang Ⅱ,and Ang-(1-7) levels by radioimmunoassay in LD group. During liver transplantation,hemodynamic parameters were determined and blood samples were obtained from the portal vein to measure renin angiotensin system(RAS) components.RESULTS:PRA,Ang Ⅰ,Ang Ⅱ and Ang-(1-7) were signifi cantly lower in the portal vein and periphery in all subgroups treated with propranolol as compared to non-treated. The relationships between Ang-(1-7) and Ang Ⅰ levels and between Ang Ⅱ and Ang Ⅰ were significantly increased in LD group receiving propranolol. The ratio between Ang-(1-7) and Ang Ⅱ remained unchanged in splanchnic and peripheral circulation in patients under β-blockade,whereas the relationship between Ang Ⅱ and Ang Ⅰ was significantly increased in splanchnic circulation of LT patients treated with propranolol. During liver transplantation,cardiac output and index as well systemic vascular resistance and index were reduced in propranolol-treated subgroup. CONCLUSION:In LD group,propranolol treatment reduced RAS mediators,but did not change the ratio between Ang-(1-7) and Ang Ⅱ in splanchnic and peripheral circulation. Furthermore,the modification of hemodynamic parameters in propranolol treated patients was not associated with changes in the angiotensin ratio. | Walkíria Wingester Vilas-Boas Antnio Ribeiro-Oliveira Jr Renata da Cunha Ribeiro Renata Lúcia Pereira Vieira Jerusa Almeida Ana Paula Nadu Ana Cristina Sim■es e Silva Robson Augusto Souza Santos | 2008 | World Journal of Gastroenterology2008，14，44： | 2 |
| 2 | Citalopram,escitalopram and prolonged QT:Warning or alarm?显示文摘 | Alvarez E Vieira S Garcia-Moll X | 2014 | Rev Psiquiatr Salud Ment2014，7，3： | 1 |
| 3 | Character- ization of the products from the pyrolysis of sewage sludge in 1 kg/h rotating cylinder reactor 显示文摘 | Pedroza M M Sousa J F Vieira G E G | 2014 | Journal of Analpical and Applied Pyrolysis2014，105，： | 1 |
| 4 | Human multipotent adipose-derived stem cells restore dystrophin expression of Duch- enne skeletal-muscle cells in vitro 显示文摘 | Vieira N M Brandalise V Zucconi E | 2008 | Biol Cell2008，100，4： | 1 |
| 5 | Photoinhibition in chilling stressed wheat and maize显示文摘 | LIDON F C LOUREIRO A S Vieira D E | 2001 | Photosynthetica2001，39，2： | 1 |
| 6 | Geographic range and body size in Neotropical marsupials显示文摘 | Olifiers N Vieira M V and Grelle C E V | 2004 | Global Ecology and Biogeography2004，13，43： | 1 |
| 7 | Boron-doped nanocrystalline silicon thin films for solar cells显示文摘 | Fathi E Vygranenko Y Vieira M | 2011 | Applied Surface Science2011，257，21： | 1 |
| 8 | Multipotent stem ceils from umbilical cord: cord is richer than blood! 显示文摘 | Secco M Zucconi E Vieira N M | 2008 | Stem Cells2008，26，1： | 1 |
| 9 | The Effect of Amine Type, PH, and Size Range in the Flotation of Quartz显示文摘 | Vieira A M Peres A E C | 2007 | Minerals Engineering2007，，20： | 1 |
| 10 | Analysis of the UDP-glucuronosyl-transferase gene in Portuguese patients with a clinical diagnosis of Gilbert and Crigler-Najjar syndromes显示文摘 | Costa E Vieira E Martins M | | 0，，01： | 1 |
| 11 | Red and processed meat and colorectal cancer incidence: meta-analysis of prospective studies显示文摘 | Chan D S Lau R Aune D Vieira R Greenwood D C Kampman E | 2011 | PLoS One2011，6，20： | 1 |
| 12 | Nitrogen and phosphorus limitation of biomass growth in a tropical secondary forest显示文摘 | DAVIDSON E A REIS DE CARVALHO C J VIEIRA I C | 2004 | Ecological Applications2004，14，4： | 1 |
| 13 | Dietary fibre, whole grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies显示文摘 | Aune D Chan D S Lau R Vieira R Greenwood D C Kampman E | 2011 | BMJ2011，343，： | 1 |
| 14 | Human multipo- tent adipose-derived stem cells restore dystrophin expres- sion of Duchenne skeletal-muscle cells in vitro显示文摘 | Vieira NM Brandalise V Zucconi E | 2008 | Biol Cell2008，100，4： | 1 |
| 15 | IRAP and REMAP assessments of genetic similarity in rice 显示文摘 | Branco C J S Vieira E A Malone G | 2007 | J Appl Genet2007，48，2： | 1 |
| 16 | The effect of amine type,pH,and size range in the flotation of quartz显示文摘 | Vieira Ana M Peres Antonio E C | 2007 | Minerals Engineering2007，20，10： | 1 |
| 17 | Statinmonotherapy attenuates renal injury in a salt-sensitive hy-pertension model of renal disease显示文摘 | Vieira JM Jr Rodrigues LT Mantovani E et a1 | 2005 | Nephron Physiol2005，101，4： | 1 |
| 18 | Evaluation of Batch Adsorption of Chromium Ions on Natural and Crosslinked Chitosan Membranes显示文摘 | BARONI P VIEIRA R S MENEGHETTI E | 2008 | Journal of Hazardous Materials2008，152，3： | 1 |
| 19 | The effects of silver nitrate and different carbohydrate sources on somatic embryogenesis in Coffea canephora显示文摘 | Fuentes S R L Calheiros M B P Manetti-Filho J Vieira L G E | | 0，，01： | 1 |
| 20 | 显示文摘 | Vieira M Rocha E Silva A Silva E | 2012 | Rev Port Cir Cardiotorac Vase2012，19，3： | 1 |
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