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| 1 | FIGL1 coordinates with dosage-sensitive BRCA2 in modulating meiotic recombination in maize显示文摘Meiotic crossover(CO)formation between homologous chromosomes ensures their subsequent proper segregation and generates genetic diversity among offspring.In maize,however,the mechanisms that modulate CO formation remain poorly characterized.Here,we found that both maize BREAST CANCER SUSCEPTIBILITY PROTEIN 2(BRCA2)and AAA-ATPase FIDGETIN-LIKE-1(FIGL1)act as positive factors of CO formation by controlling the assembly or/and stability of two conserved DNA recombinases RAD51 and DMC1 filaments.Our results revealed that Zm BRCA2 is not only involved in the repair of DNA double-stranded breaks(DSBs),but also regulates CO formation in a dosage-dependent manner.In addition,Zm FIGL1interacts with RAD51 and DMC1,and Zmfigl1 mutants had a significantly reduced number of RAD51/DMC1 foci and COs.Further,simultaneous loss of Zm FIGL1 and Zm BRCA2 abolished RAD51/DMC1foci and exacerbated meiotic defects compared with the single mutant Zmbrca2 or Zmfigl1.Together,our data demonstrate that Zm BRCA2 and Zm FIGL1 act coordinately to regulate the dynamics of RAD51/DMC1-dependent DSB repair to promote CO formation in maize.This conclusion is surprisingly different from the antagonistic roles of BRCA2and FIGL1 in Arabidopsis,implying that,although key factors that control CO formation are evolutionarily conserved,specific characteristics have been adopted in diverse plant species. | Ting Zhang Shuang‐Hui Zhao Yan Wang Yan He | 2023 | Journal of Integrative Plant Biology2023，65，9： | 0 |
| 2 | EGR 1 is critical for gastrin‐dependent upregulation of anion exchanger 2 in gastric cancer cells显示文摘 | Ting Wang Lei Zhao Ye Yang Hua Tian Wen‐Hao Suo Min Yan Guo‐Hui Fu | 2012 | FEBS J2012，，1： | 1 |
| 3 | HPLC‐FLD determination of NBD‐cholesterol, its ester and other metabolites in cellular lipid extracts显示文摘 | Xiu‐zhen Cao Ting‐yan Mi Lin Li Mario A. Vermeer Chen‐chen Zhang Nan Huang Joshi K. Manoj | 2013 | Biomed. Chromatogr2013，，7： | 1 |
| 4 | Targeting of DICE1 tumor suppressor by Epstein–Barr virus‐encoded miR‐BART3* microRNA in nasopharyngeal carcinoma显示文摘 | Ting Lei Kit‐San Yuen Rui Xu Sai Wah Tsao Honglin Chen Mengfeng Li Kin‐Hang Kok Dong‐Yan Jin | 2013 | Int J Cancer2013，，1： | 1 |
| 5 | Confocal endomicroscopy for in vivo detection of microvascular architecture in normal and malignant lesions of upper gastrointestinal tract显示文摘 | HongLiu Yan‐QingLi TaoYu You‐AnZhao Jian‐PingZhang Jian‐NaZhang Yu‐TingGuo Xiang‐JunXie Ting‐GuoZhang Paul VDesmond | 2007 | Journal of Gastroenterology and Hepatology2007，，： | 1 |
| 6 | Expression patterns of histone deacetylases in experimental stroke and potential targets for neuroprotection显示文摘 | Yan‐Ting Chen Xue‐Feng Zang Jie Pan Xiao‐Lei Zhu Fei Chen Zhi‐Bin Chen Yun Xu | 2012 | Clin Exp Pharmacol Physiol2012，，9： | 1 |
| 7 | Confocal endomicroscopy for in vivo detection of microvascular architecture in normal and malignant lesions of upper gastrointestinal tract显示文摘 | HongLiu Yan‐QingLi TaoYu You‐AnZhao Jian‐PingZhang Jian‐NaZhang Yu‐TingGuo Xiang‐JunXie Ting‐GuoZhang Paul VDesmond | 2007 | Journal of Gastroenterology and Hepatology2007，，1： | 1 |
| 8 | Large primary hepatocellular carcinoma: Transarterial chemoembolization monotherapy versus combined transarterial chemoembolization‐percutaneous microwave coagulation therapy显示文摘 | Lin‐Feng Xu Hong‐Liang Sun Yao‐Ting Chen Jia‐Yan Ni Dong Chen Jiang‐Hong Luo Jing‐Xing Zhou Ren‐Mei Hu Qi‐Yun Tan | 2013 | J Gastroenterol Hepatol2013，，： | 2 |
| 9 | Large primary hepatocellular carcinoma: Transarterial chemoembolization monotherapy versus combined transarterial chemoembolization‐percutaneous microwave coagulation therapy显示文摘 | Lin‐Feng Xu Hong‐Liang Sun Yao‐Ting Chen Jia‐Yan Ni Dong Chen Jiang‐Hong Luo Jing‐Xing Zhou Ren‐Mei Hu Qi‐Yun Tan | 2013 | J Gastroenterol Hepatol2013，，3： | 1 |
| 10 | MicroRNA ‐30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS , PIK3CD and BCL2显示文摘 | Wen‐Ting Liao Ya‐Ping Ye Nian‐Jie Zhang Ting‐Ting Li Shu‐Yang Wang Yan‐Mei Cui Lu Qi Ping Wu Hong‐Li Jiao Yi‐Jun Xie Chi Zhang Jun‐Xian Wang Yan‐Qing Ding | 2014 | J. Pathol2014，，4： | 1 |
| 11 | CaWRKY40, a WRKY protein of pepper, plays an important role in the regulation of tolerance to heat stress and resistance to Ralstonia solanacearum infection显示文摘 | FENG‐FENG DANG YU‐NA WANG LU YU THOMAS EULGEM YAN LAI ZHI‐QIN LIU XU WANG AI‐LIAN QIU TING‐XIU ZHANG JING LIN YAN‐SHENG CHEN DE‐YI GUAN HAN‐YANG CAI SHAO‐LIANG MOU SHUI‐LIN HE | 2012 | Plant, Cell & Environment2012，，： | 2 |
| 12 | Entecavir treatment reduces hepatic events and deaths in chronic hepatitis B patients With liver cirrhosis显示文摘 | Grace Lai‐Hung Wong Henry Lik‐Yuen Chan Christy Wing‐Hin Mak Stanley King‐Yeung Lee Zoe Man‐Yi Ip Andrew Ting‐Ho Lam Henry Wing‐Hang Iu Joyce May‐Sum Leung Jennifer Wing‐Yan Lai Angeline Oi‐Shan Lo Hoi‐Yun Chan Vincent Wai‐Sun Wong | 2013 | Hepatology2013，，5： | 1 |
| 13 | Genetic variations of mTORC1 genes and risk of gastric cancer in an eastern chinese population显示文摘 | Jing He Meng‐Yun Wang Li‐Xin Qiu Mei‐Ling Zhu Ting‐Yan Shi Xiao‐Yan Zhou Meng‐Hong Sun Ya‐Jun Yang Jiu‐Cun Wang Li Jin Ya‐Nong Wang Jin Li Hong‐Ping Yu Qing‐Yi Wei | 2013 | Carcinog2013，，1： | 1 |
| 14 | MicroRNA‐125b attenuates epithelial‐mesenchymal transitions and targets stem‐like liver cancer cells through small mothers against decapentaplegic 2 and 4显示文摘 | Jun‐Nian Zhou Quan Zeng Hai‐Yang Wang Biao Zhang Si‐Ting Li Xue Nan Ning Cao Chun‐Jiang Fu Xin‐Long Yan Ya‐Li Jia Jing‐Xue Wang Ai‐Hua Zhao Zhi‐Wei Li Yan‐Hua Li Xiao‐Yan Xie Xiao‐Mei Zhang Yan Dong Ying‐Chen Xu Li‐Juan He Wen Yue Xue‐Tao Pei | 2015 | Hepatology2015，，3： | 1 |
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