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| 1 | Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: A perspective on Asia显示文摘 | Tin Nguyen Alexander J.V. Thompson Scott Bowden Catherine Croagh Sally Bell Paul V. Desmond Miriam Levy Stephen A. Locarnini | 2010 | Journal of Hepatology2010，，4： | 7 |
| 2 | Efficacy and safety of tenofovir in chronic hepatitis B: Australian real world experience显示文摘AIM To evaluate the long-term treatment outcomes of tenofovir therapy in patients in a real world Australian tertiary care setting.METHODS We performed a retrospective analysis of treatment outcomes among treatment-na?ve and treatment-experienced patients receiving a minimum 3 mo tenofovir therapy through St Vincent's Hospital Melbourne, Australia. We included patients receiving tenofovir [tenofovir disoproxil fumarate(TDF)] monotherapy, as well as patients treated with TDF in combination with a second antiviral agent. Patients were excluded if they demonstrated human immune-deficiency virus/hepatitis C virus/hepatitis delta virus coinfection or were less than 18 years of age. We considered virological and biochemicalresponse, as well as safety outcomes. Virological response was determined by measurement of hepatitis B virus(HBV) DNA using sensitive assays; biochemical response was determined via serum liver function tests; histological response was determined from liver biopsy and fibroscan; safety analysis focused on glomerular renal function and bone mineral density. The primary efficacy endpoint was complete virological suppression over time, defined by HBV DNA < 20 IU/m L. Secondary efficacy endpoints included rates of biochemical response, and HB e antigen(HBe Ag)/HB surface antigen loss and seroconversion over time.RESULTS Ninety-two patients were identified who fulfilled the enrolment criteria. Median follow-up was 26 mo(range 3-114). Mean age was 46(24-78) years, 64(70%) were male and 77(84%) were of Asian origin. 55(60%) patients were treatment-na?ve and 62 patients(67%) were HBe Ag-negative. Complete virological suppression was achieved by 45/65(71%) patients at 12 mo, 37/46(80%) at 24 mo and 25/28(89%) at 36 mo. Partial virological response(HBV DNA 20-2000 IU/m L) was achieved by 89/92(96.7%) of patients. Multivariate analysis showed a significant relationship between virological suppression at end of follow-up and baseline HBV DNA level(OR = 0.897, 95%CI: 0.833-0.967, P = 0.0046) and HBe Ag positive status(OR = 0.373, 95%CI: 0.183-0.762, P = 0.0069). There was no difference in response comparing treatment-na?ve and treatment-experienced patients. Three episodes of virological breakthrough occurred in the setting of noncompliance. Tenofovir therapy was well tolerated.CONCLUSION Tenofovir is an efficacious, safe and well-tolerated treatment in an Australian real-world tertiary care setting. Our data are similar to the reported experience from registration trials. | Grace C Lovett Tin Nguyen David M Iser Jacinta A Holmes Robert Chen Barbara Demediuk Gideon Shaw Sally J Bell Paul V Desmond Alexander J Thompson | 2017 | World Journal of Hepatology2017，9，1： | 7 |
| 3 | Comparison of Cold and Warm Ischemia During Partial Nephrectomy in 660 Solitary Kidneys Reveals Predominant Role of Nonmodifiable Factors in Determining Ultimate Renal Function显示文摘 | Brian R. Lane Paul Russo Robert G. Uzzo Adrian V. Hernandez Stephen A. Boorjian R. Houston Thompson Amr F. Fergany Thomas E. Love Steven C. Campbell | 2011 | The Journal of Urology2011，，2： | 3 |
| 4 | Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | E. Sander Connolly Alejandro A. Rabinstein J. Ricardo Carhuapoma Colin P. Derdeyn Jacques Dion Randall T. Higashida Brian L. Hoh Catherine J. Kirkness Andrew M. Naidech Christopher S. Ogilvy Aman B. Patel B. Gregory Thompson Paul Vespa | 2012 | Stroke2012，，6： | 3 |
| 5 | 细胞分离培养在实验室诊断眼部单纯疱疹病毒感染疾病的误诊和漏诊情况(英文)显示文摘目的:对比聚合酶链反应(PCR)和细胞分离培养在实验室诊断眼部单纯疱疹病毒(HSV)感染疾病的作用。方法:我们对连续患者的实验室结果(PCR实验,细胞分离培养及临床诊断)及病历进行回顾性研究在诊断眼部HSV感染疾病过程中,PCR检测结果、细胞分离培养及首诊结果进行了统计比较。结果:患者581例经过检查后,520例PCR检查阴性,细胞培养阴性(89.6%);0例PCR检查阴性,细胞培养阳性(0%);27例PCR检查阳性,细胞培养阴性(4.6%);34例PCR检查阳性,细胞培养阳性(5.8%)。PCR检测阳性率高于细胞分离培养(McNemars,P=0.0001)。47例PCR检查为HSV初诊感染阳性患者中,19例患者中有14例为细胞培养阴性结果(74%),5例HSV患者因缺PCR检测结果将被误诊;28例患者中有25例患者细胞培养阳性(占89%),3例HSV患者因缺PCR检测结果将被漏诊。结论:PCR诊断眼部HSV感染优于细胞分离培养。细胞分离培养对于眼部HSV感染的非典型表现不易诊断。 | Regis P Kowalski Paul P Thompson Tara H Cronin | 2010 | 国际眼科杂志2010，10，11： | 2 |
| 6 | Primary biliary cirrhosis, hyperlipidemia, and atherosclerotic risk: A systematic review显示文摘 | Alexey Sorokin Jennifer L. Brown Paul D. Thompson | 2006 | Atherosclerosis2006，，2： | 2 |
| 7 | Irritable bowel syndrome in female patients is associated with alterations in structural brain networks显示文摘 | Jennifer S. Labus Ivo D. Dinov Zhiguo Jiang Cody Ashe-McNalley Alen Zamanyan Yonggang Shi Jui-Yang Hong Arpana Gupta Kirsten Tillisch Bahar Ebrat Sam Hobel Boris A. Gutman Shantanu Joshi Paul M. Thompson Arthur W. Toga Emeran A. Mayer | 2014 | Pain2014，，1： | 2 |
| 8 | Efficacy of aprepitant in patients receiving high-dose chemotherapy with hematopoietie stem cell sUpport显示文摘 | Paul B Trovato JA Thompson J | 2010 | J Oncol Pharm Pratt2010，16，1： | 1 |
| 9 | Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: A perspective on Asia显示文摘 | Tin Nguyen Alexander J.V. Thompson Scott Bowden Catherine Croagh Sally Bell Paul V. Desmond Miriam Levy Stephen A. Locarnini | 2010 | Journal of Hepatology2010，，4： | 1 |
| 10 | Exercise and acute cardiovascular events : placing the risks into perspective 显示文摘 | PAUL D THOMPSON M D BARRY A | 2007 | Circulation2007，115，17： | 1 |
| 11 | Transitivity in Grammar and Discourse 显示文摘 | Hopper Paul & Sandra Thompson | 1980 | Language1980，56，： | 1 |
| 12 | Optimization of the enzyme-linked lectin assay for enhanced glycoprotein and glycoconjugate analysis显示文摘 | Roisin Thompson Aileen Creavin Michael O'Connell Brendan O'Connor Paul Clarke | 2011 | Analytical Biochemistry2011，，2： | 1 |
| 13 | Corporate Social Responsibility Reporting in Malaysia:Progress and Prospects显示文摘 | Paul Thompson Zarina Zakaria | 2006 | The Journal of Corporate Citizenship2006，，13： | 1 |
| 14 | OralHis- to-ry in China显示文摘 | Stephen Thompson Paul Thompson and Yang Liwen | 1987 | Oral HistoryJournal(England)1987，，15： | 1 |
| 15 | The use of physical biomodelling in complex spinal surgery显示文摘 | Maree T. Izatt Paul L. P. J. Thorpe Robert G. Thompson Paul S. D’Urso Clayton J. Adam John W. S. Earwaker Robert D. Labrom Geoffrey N. Askin | 2007 | European Spine Journal2007，，9： | 1 |
| 16 | Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | E. Sander Connolly Alejandro A. Rabinstein J. Ricardo Carhuapoma Colin P. Derdeyn Jacques Dion Randall T. Higashida Brian L. Hoh Catherine J. Kirkness Andrew M. Naidech Christopher S. Ogilvy Aman B. Patel B. Gregory Thompson Paul Vespa | 2012 | Stroke2012，，6： | 1 |
| 17 | Association of Contemporary Sensitive Troponin I Levels at Baseline and Change at 1 Year With Long-Term Coronary Events Following Myocardial Infarction or Unstable Angina显示文摘 | Harvey D. White Andrew Tonkin John Simes Ralph Stewart Kristy Mann Peter Thompson David Colquhoun Malcolm West Paul Nestel David Sullivan Anthony C. Keech David Hunt Stefan Blankenberg | 2014 | Journal of the American College of Cardiology2014，，4： | 1 |
| 18 | Cell culture isolation can miss the laboratory diagnosis of HSV ocular infection显示文摘AIM:We compared polymerase chain reaction(PCR)to cell culture isolation for the laboratory diagnosis of ocular herpes simplex virus(HSV)disease. ? METHODS:Laboratory and medical records of consecutive patients were reviewed for results of 1)HSV PCR testing,2) HSV cell culture isolation,and 3)clinical diagnosis.PCR results were statistically compared to cell culture isolation and patients initially diagnosed for ocular HSV infection. RESULTS:Of 581 cases submitted for laboratory testing, 520 were PCR negative,cell culture negative(89.6%);0 were PCR negative,cell culture positive(0%);27 were PCR positive,cell culture negative(4.6%);and 34 were PCR positive,cell culture positive(5.8%).PCR tested more positive than cell culture isolation(McNemar’s,P=0.0001).Of 47 HSV PCR positive cases with complete medical records,19 were cell culture negative for HSV and 28 were cell culture positive for HSV.Fourteen of 19 cell culture negative cases (74%)(Without PCR,5 cases of HSV would be missed)and 25 of the 28 cell culture positive cases(89%)(Laboratory testing was necessary for diagnosing 3 cases)were clinically diagnosed with HSV at the initial examination. CONCLUSION:PCR was a more definitive test for diagnosing HSV ocular infection than cell culture isolation.Cell culture isolation alone can miss an atypical presentation of HSV ocular infection. | Regis P Kowalski Paul P Thompson Tara H Cronin | 2010 | International Journal of Ophthalmology(English edition)2010，3，2： | 1 |
| 19 | Flame retardant aircraft epoxy resin containing phosphorus显示文摘 | PAUL M HERGENROTHER C M THOMPSON J G | 2005 | Polymer2005，46，14： | 1 |
| 20 | Obesity is linked with lower brain volume in 700 AD and MCI patients显示文摘 | April J. Ho Cyrus A. Raji James T. Becker Oscar L. Lopez Lewis H. Kuller Xue Hua Suh Lee Derrek Hibar Ivo D. Dinov Jason L. Stein Clifford R. Jack Michael W. Weiner Arthur W. Toga Paul M. Thompson | 2010 | Neurobiology of Aging2010，，8： | 1 |
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