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| 1 | Inflammatory bowel disease:Therapeutic limitations and prospective of the stem cell therapy显示文摘Inflammatory bowel disease(IBD),consisting primarily of ulcerative colitis and Crohn’s disease,is a group of debilitating auto-immune disorders,which also increases the risk of colitis-associated cancer.However,due to the chronic nature of the disease and inconsistent treatment outcomes of current anti-IBD drugs(e.g.,approximately 30%non-responders to anti-TNFαagents),and related serious side effects,about half of all IBD patients(in millions)turn to alternative treatment options.In this regard,mucosal healing is gaining acceptance as a measure of disease activity in IBD patients as recent studies have correlated the success of mucosal healing with improved prognosis.However,despite the increasing clinical realization of the significance of the concept of mucosal healing,its regulation and means of therapeutic targeting remain largely unclear.Here,stemcell therapy,which uses hematopoietic stem cells or mesenchymal stem cells,remains a promising option.Stem cells are the pluripotent cells with ability to differentiate into the epithelial and/or immune-modulatory cells.The overreaching concept is that the stem cells can migrate to the damaged areas of the intestine to provide curative help in the mucosal healing process.Moreover,by differentiating into the mature intestinal epithelial cells,the stem cells also help in restoring the barrier integrity of the intestinal lining and hence prevent the immunomodulatory induction,the root cause of the IBD.In this article,we elaborate upon the current status of the clinical management of IBD and potential role of the stem cell therapy in improving IBD therapy and patient’s quality of life. | Rangnath Mishra Punita Dhawan Anand S Srivastava Amar B Singh | 2020 | World Journal of Stem Cells2020，12，10： | 4 |
| 2 | Data Preparation for Mining World Wide Web Browing Patterns显示文摘 | MOBASHER B SRIVASTAVA J | 1999 | Journal of Knowledge and Information System1999，，： | 1 |
| 3 | Data preparation for mining world wide web browsing patterns显示文摘 | Cooley R Mobasher B Srivastava J | 1999 | Knowledge and Information Systems1999，，1： | 1 |
| 4 | Data preparation for mining world wide Web browsing patterns显示文摘 | Cooley R Mobasher B Srivastava J | 1999 | Journal of Knowledge and Information Systems1999，1，1： | 1 |
| 5 | Spray forming of Al-Si-Pb alloys and their wear characteristics显示文摘 | Rudrakshi G B Srivastava V C Pathak J P | 2004 | Materials Science and Engineering A2004，383，： | 1 |
| 6 | Data preparation for mining wodd wide web browsing pattems显示文摘 | Cooley R Mobasher B Srivastava J | 1999 | Knowledge and Information Systems1999，1，1： | 1 |
| 7 | Data Preparation for mining World Wide Web Browsing Patterns显示文摘 | Cooley R Mobasher B Srivastava J | 1999 | Knowledge and Information System1999，1，1： | 1 |
| 8 | New Antifungal Constituents from Terminalia alata显示文摘 | SRIVASTAVA S K SRIVASTAVA S D CHOUKSEY B K | 2001 | Fitoterapia2001，72，： | 1 |
| 9 | Automatic personalization based on Web usage mining显示文摘 | MDBASHER B COOLEY R SRIVASTAVA J | 2000 | Communications of the ACM2000，43，8： | 1 |
| 10 | Evidence for close asso- ciation of POD polyphenoloxidase and IAA oxidase isoenzyme of peanut suspension culture medium 显示文摘 | Srivastava O P Van Huystee P B | 1973 | Can J Bot1973，51，： | 1 |
| 11 | Anti - inflammatory and anti- pyretic activities of 13 - sitosterol 显示文摘 | Gupta M B Nath R Srivastava N | 1980 | Planta medica1980，39，6： | 1 |
| 12 | ANXA7 expression represents hormone-relevant tumor suppression in different cancers显示文摘 | Srivastava M Torosyan Y Raffeld M Eidelman O Pollard H B Bubendorf L | 2007 | Int J Cancer2007，121，： | 1 |
| 13 | Lipid peroxidation-derived aldehydes and oxidative stress in the failing heart:role of aldose reductase显示文摘 | Srivastava S Chandrasekar B Bhatnagar A | 2002 | Am J Physiol2002，283，： | 1 |
| 14 | Synthesis and hydrogenation behaviour of graphitic nanofibres显示文摘 | Gupta B K Srivastava O N | 2000 | Int J Hydrogen Energy2000，25，： | 1 |
| 15 | Enhancements in conductivity and thermal stabilities of polypyrrole/polyurethane nanoblends显示文摘 | Kotal M Srivastava S K Paramanik B | 2011 | J Phys Chem C2011，115，5： | 1 |
| 16 | Data preparation for mining world wide Web browsing patterns显示文摘 | COOLEY R MOBASHER B SRIVASTAVA J | 1999 | Knowledge and Information Systems1999，1，1： | 1 |
| 17 | Protective effects of indole-3-carbinol on cyclophosphamide-induced clastogenecity in mouse bone marrow cells显示文摘 | SHUKLA Y SRIVASTAVA B ARORA A | 2004 | Hum Exp Toxicol2004，23，： | 1 |
| 18 | Inhibi- tion of aldose reductase preve - nts angiogenesis in vitro and in vivo显示文摘 | Tammali R Reddy A B Srivastava S K | 2011 | Angiogenesis2011，14，： | 1 |
| 19 | PNUTS:Yahoo! 's hosted data serving platfbrm显示文摘 | ] COOPER B F RAMAKRISHNAN R SRIVASTAVA U | 2008 | Proceed- ings of the VLDB Endowment2008，，2： | 1 |
| 20 | The traditional Chinese herbal formula ASHMI inhibits allergic lung inflammationin antigen-sensitized and antigen-challenged aged mice显示文摘 | Busse P J Schofield B Birmingham N Yang N Wen MC Zhang T Srivastava K Li XM | | 0，，03： | 1 |
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