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    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B 2020中华高血压杂志2020,28,3:22
3健康成人动脉粥样硬化斑块易感性和血栓形成的生物标志物变化与极端空气污染水平相关:北京AIRCHD研究显示文摘空气污染与心血管事件恶化的病理生理机制尚不完全清楚。该文探讨环境空气污染是否可以触发易损斑块.通过全身炎症途径促进血栓形成。方法:在北京AIRCHD研究中.2014-2016年间对73名健康成年人[年龄(23.3±5.4)岁]进行了随访。研究者使用线性混合效应模型评估了空气污染物与动脉粥样硬化斑块易损性、血栓形成和炎症相关生物标志物之间的关系,并使用中介效应分析(mediation analyses)探讨涉及的生物学途径。通过受试者工作特征(receiver operating characteristic,ROC)曲线分析评估每种生物标记物预测环境空气污染暴露的能力。刘青 叶鹏 Xu H Wang T Liu S Brook RD Feng B Zhao Q Song X Yi T Chen J Zhang Y Wang Y Zheng L Rajagopalan S Li J Huang W 2019中华高血压杂志2019,27,4:13
4Mutation analysis of autosomal dominant polycystic kidney disease genes in Han Chinese显示文摘Zhang S Mei C Zhang D Dai B Tang B Sun T Zhao H Zhou Y Li L Wu Y Wang W Shen X Song J 2005第二军医大学学报2005,26,8:6
5血浆7-酮胆固醇与冠状动脉疾病患者心血管结局和总死亡率的关系显示文摘7-酮胆固醇(7-ketocholesterol,7-KC)是胆固醇氧化产物的一种形式,在动物动脉粥样硬化模型的形成中起重要作用。该文研究人员试图确定循环7-KC与稳定型冠状动脉疾病(coronary artery disease,CAD)患者的临床心血管结局和总死亡率的关系。刘莉 叶鹏 Song J Wang D Chen H Huang X Zhong Y Jiang N Chen C Xia M 2017中华高血压杂志2017,25,6:4
6Research and experiments of the dynamical model system for short-term climate prediction显示文摘Ding Y H Liu Y .M Song J 气候与环境研究0,,:2
7Time delayed repetitive learning control for chaotic systems显示文摘Song Y X Yu X H Chen G R 2002International Journal of Bifurcation and Chaos2002,12,5:2
8Terahertz Semiconductor Quantum Well Devices显示文摘For eventually providing terahertz science with compact and convenient devices,terahertz (1~10THz) quantum-well photodetectors and quantum-cascade lasers are investigated.The design and projected detector performance are presented together with experimental results for several test devices,all working at photon energies below and around optical phonons.Background limited infrared performance (BLIP) operations are observed for all samples (three in total),designed for different wavelengths.BLIP temperatures of 17,13,and 12K are achieved for peak detection frequencies of 9.7THz(31μm),5.4THz(56μm),and 3.2THz(93μm),respectively.A set of THz quantum-cascade lasers with identical device parameters except for doping concentration is studied.The δ-doping density for each period varies from 3.2×1010 to 4.8×1010cm-2.We observe that the lasing threshold current density increases monotonically with doping concentration.Moreover,the measurements for devices with different cavity lengths provide evidence that the free carrier absorption causes the waveguide loss also to increase monotonically.Interestingly the observed maximum lasing temperature is best at a doping density of 3.6×1010cm-2.Liu H C Luo H Ban D Waichter M Song C Y Wasilewski Z R Buchanan M Aers G C SpringThorpe A J Cao J C Feng S L Williams B S Hu Q 2006Journal of Semiconductors2006,27,4:2
9Amino functionalized ionic liquid as an efficient and recyclable catalyst for knoevenagel reactions in water 显示文摘Cai Y Q Peng Y Q Song G H 2006Catal Lett2006,109,:1
10A Multidimensional Trust Formation Model in B-to-C Ecommerce:A Conceptual Framework and Content Analyses of Academia/Practitioner Perspectives 显示文摘Kim D J Song Y I Braynov S B Rao H R 2005Decision Support Systems2005,40,2:1
11High corrosion resistance of electroless composite plating coatings on AZ91D magnesium alloys 显示文摘SONG Y W SHAN D Y CHEN R S HAN E H 2008Electrochimica Acta2008,53,:1
12Nutrients removal and recovery by crystallization of magnesium ammonium phosphate from synthetic swine wastewater显示文摘SONG Y H YUAN P ZHENG B H 2007Chemosphere2007,69,2:1
13Macrolide resistance and genotypic characterization of streptococcus pneumoniae in Asian countries:a study of the Asian NETWORK FOR Surveillance of Resistance Pathogens (ANSOP)显示文摘SONG J H CHANG H H SUH J Y 2004J Antimicrob Chemother2004,53,3:1
14Novel chemical method for synthesis of LiV3 O8 nanorods as cathode materials for lithium ion batteries 显示文摘Xu H Y Wang H Song Z Q 2004Electrochimica Acta2004,49,2:1
15YAG laser percussion drilling of a functional multi-layer thin plate 显示文摘WANG A H WANG W Y BAI Z K XIE C S ZENG D W SONG W L 2007Optics & Laser Technology2007,39,:1
16Amino functionalized ionic liquid as an efficient and recyclable catalyst for knoevenagel reactions in water显示文摘Cai Y Q Peng Y Q Song G H 2006Catalysis Letters2006,109,12:1
17Thermal and morphological effects of the pulsed Nd: YAG laser on root canal surfaces显示文摘He H Yu J Song Y 2009Photomed Laser Surg2009,27,2:1
18A novel high perf ormance RTM resin based on benzoxazine显示文摘Xiang H Ling H Wang J Song L Gu Y 2005Polymer Composites2005,26,5:1
19Restriction endonuclease analysis of canine parvorirus DNA isolated in Korea显示文摘Park J H Song J Y 1992Vet Res1992,32,4:1
20Biochemical markers comparison of dynamic hip screw and gamma nail implants in the treatment of stable intertrochanteric fracture: a prospective study of 60 patients 显示文摘Song W Chen Y Shen H 2011J Int Med Res2011,39,3:1
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