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| 1 | Pediatric functional constipation treatment with Bifi dobacterium-containing yogurt:A crossover,double-blind,controlled trial显示文摘AIM: To evaluate the treatment of pediatric functional chronic intestinal constipation (FCIC) with a probiotic goat yogurt. METHODS: A crossover double-blind formula-controlled trial was carried out on 59 students (age range: 5-15 years) of a public school in Belo Horizonte, MG, Brazil, presenting a FCIC diagnostic, according to Roma Ⅲ criteria. The students were randomized in two groups to receive a goat yogurt supplemented with 109 colony forming unit/mL Bifidobacterium longum (B.longum) (probiotic) daily or only the yogurt for a period of 5 wk (formula). Afterwards, the groups were intercrossed for another 5 wk. Defecation frequency, stool consistency and abdominal and defecation pain were assessed.RESULTS: Both treatment groups demonstrated improvement in defecation frequency compared to baseline. However, the group treated with probiotic showed most signif icant improvement in the f irst phase of the study. An inversion was observed after crossing over, resulting in a reduction in stool frequency when this group was treated by formula. Probiotic and formula improved stool consistency in the f irst phase of treatment, but the improvement obtained with probiotic was significantly higher (P = 0.03). In the second phase of treatment, the group initially treated with probiotic showed worseningstool consistency when using formula. However, the difference was not signif icant. A signif icant improvement in abdominal pain and defecation pain was observed with both probiotic and formula in the first phase of treatment, but again the improvement was more signif icant for the group treated with B. longum during phase I (P < 0.05). When all data of the crossover study were analyzed, significant differences were observed between probiotic yogurt and yogurt only for defecation frequency (P = 0.012), defecation pain (P = 0.046) and abdominal pain (P = 0.015). | Paula VP Guerra Luiza N Lima Tassia C Souza Vanessa Mazochi Francisco J Penna Andreia M Silva Jacques R Nicoli Elizabet V Guimares | 2011 | World Journal of Gastroenterology2011，17，34： | 25 |
| 2 | 固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验显示文摘控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。 | Web-ster R Salam A de Silva HA Selak V Stepien S Rajapakse S Amarasekara S Amarasena N Billot L de Silva AP Fernando M Guggilla R Jan S Jayawardena J Maulik PK Mendis S Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom S Tisserra N Senaratne V Wijekoon S Wijeyasingam S Rodgers A Patel A 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 7 |
| 3 | Energetic-protein supplementation in the last 60 days of gestation improves performance of beef cows grazing tropical pastures显示文摘Background: Nutrition is one of the most important factors that affect animal performance, and it therefore also impacts on financial results in beef systems. In this way, finding the best strategy for feeding supplements is of paramount importance. Aiming to evaluate the effect of supplement feeding strategies for beef cows in the last third of gestation, two experiments were conducted. In Experiment 1, 35 pregnant Nellore cows were assigned to a completely randomized design with four treatments: control, which received no supplement; supplementation for the last 30 d of gestation(30-d; 3.0 kg/d); supplementation for the last 60 d of gestation(60-d; 1.5 kg/d); or supplementation for the last 90 d of gestation(90-d; 1.0 kg/d). All supplemented treatments received the same total amount of supplement throughout the experiment: 90 kg(20% of crude protein). A second experiment(Experiment 2) was delineated to evaluate the effects of the amounts offered in Experiment 1 on intake and metabolism. Four multiparous pregnant Nellore cows were assigned to a 4 × 4 Latin square design, with periods of15 d each.Results: There was a linear effect of the number of days of supplementation on calving body weight(BW; P < 0.05)and a quadratic effect on BW change from parturition to d 31 post-calving(P < 0.05), with cows on the 60-d strategy losing less BW post-calving. No difference was found in offspring birth BW(P > 0.10). A significant linear effect on interval from parturition to conception(P < 0.05) was observed, with the highest calving to conception interval being observed in the 90-d strategy. The level of supplementation did not affect forage intake or neutral detergent fiber digestibility(P > 0.10). Nitrogen excreted through urine tended to increase linearly with the level of supplementation(P < 0.10).Conclusion: Providing 1.5 kg of supplement during the last 60 d of gestation improves cow performance after calving, reducing the magnitude of BW lost, and reduces the number of days from calving to re-conception in the following breeding season compared to the usually recommended period of supplementation of 90 d pre-partum. | Aline Gomes da Silva Mário Fonseca Paulino Edenio Detmann Henrique Jorge Fernandes Lincoln da Silva Amorim Román Enrique Maza Ortega Victor Valério de Carvalho Josilaine Aparecida da Costa Lima Felipe Henrique de Moura Mariana Benevides Monteiro Jéssika Almeida Bitencourt | 2018 | Journal of Animal Science and Biotechnology2018，9，1： | 2 |
| 4 | Chitosan-based femimagnetic membrane显示文摘 | M A Mace^do M N B Silva A R Cestari | 2004 | Physica B2004，，354： | 1 |
| 5 | Electrocatalytic and Voltammetric Determination of Sulfhydryl Compounds Through Iron Nitroprusside Modifeid Graphite Paste Clectrode显示文摘 | Carmo D R Silva R M Satradiotto N R | 2003 | J Braz Chem Soc2003，14，4： | 1 |
| 6 | Distribution and viral load of eight ancogenic types of human papillomavirus (HPV) and HPV 16 integration status in cervical intraepithelial neoplasia and carcinoma显示文摘 | Guo M Sneige N Silva EG | 2007 | Mod Pathol2007，20，2： | 1 |
| 7 | Effects of polyphenol-oxidase and peroxidase activity’phenolics and iign incon tentonthe browning of cut jicama 显示文摘 | Aquino-Bolanos E N Silva E M | 2004 | PostharvestBiology andTechnology2004，33，3： | 1 |
| 8 | Oxygen free radical scavenger capacity in aqueous models of different procya- nidins from grape seeds显示文摘 | RICARDO DA SILVA J M DARMON N FERNANDEZ Y | 1991 | Journal of Agricultural and Food Chemistry1991，39，9： | 1 |
| 9 | Rational therapeutic approaches to progressive supranuclear palsy显示文摘 | Stamelou M de Silva R Arias-carri o n O | 2010 | Brain2010，133，6： | 1 |
| 10 | Why men stillget more promotions than women显示文摘 | IBARRA H CARTER N M SILVA C | 2010 | Harvard Business Review2010，88，9： | 1 |
| 11 | Comparison of root-system efficiency and arsenic up- take of two fern Species 显示文摘 | SILVA GONZAGA M I SANTOS J A G COMERFORD N B | 2007 | Communications in Soil Science and Plant Analysis2007，38，： | 1 |
| 12 | A simple and effective inverse projection scheme for void distri- bution control in topology optimization 显示文摘 | Almeida S R M Paulino G H Silva E C N | 2009 | Structur- al and Multidisciplinary Optimization2009，39，4： | 1 |
| 13 | The use of ultrasonic guided waves and wavelets analysis in pipe inspection显示文摘 | SIQUEIRA M H S GATTS C E N SILVA R R | 2004 | Ultrasonic2004，41，： | 1 |
| 14 | Integration of logic functions and sequential operation of gates at the molecu- lar-scale显示文摘 | de Silva A P Dixon I M Gunaratne H Q N | 1999 | J Am Chem Soc1999，121，6： | 1 |
| 15 | Effect of key operating parameters on phenols degrada-tion during H2O2-assisted TiO2 photocatalytic treat-ment of simulated and actual olive mill wastewaters 显示文摘 | Silva A M T Nouli E Xekoukoulotakis N P | 2007 | Appl Catal B: Environ2007，73，12： | 1 |
| 16 | Distribution and viral load of eight oncogenic types of human papillomavirus (HPV) and HPV 16 integration status in cervical intraepithelial neoplasia and carcinoma显示文摘 | Guo M Sneige N Silva EG | | 0，，02： | 1 |
| 17 | The transmissibility concept in multiple degrees of freedom systems 显示文摘 | Maia N M M Silva J M M Ribeiro A M R | 2001 | Mechanical Systems and Signal Processing2001，15，1： | 1 |
| 18 | Development and characterization of phosphatidylcholine nanovesicles containing the antimicrobial peptide nisin 显示文摘 | DA SILVA MALHEIROS P MICHELETTO Y M S DA SILVEIRA N P | 2010 | Food Res Inter2010，43，4： | 1 |
| 19 | The application of FAMM (fluorescence alteration of multiple macerals) analyses for evaluating rank of Parana basin coal, Brazil 显示文摘 | Kalkreuth W Sherwood N Cioccari G Silva C D Silva M Zhong N Zufa L | 2004 | International Journal of Coal Geology2004，57，： | 1 |
| 20 | Measurements and numerical simulations of the degree of activity and vegetation cover on parabolic dunes in north-eastern Brazil显示文摘 | Duran O Silva M V N Bezerra L J C | 2008 | Geomorphology2008，102，34： | 1 |
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