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| 1 | 母猪妊娠期营养对窝产仔猪初生重整齐度的影响显示文摘母猪窝产仔猪初生重整齐度差导致生猪生产效率降低,研究母猪妊娠期间营养需求满足母猪和胎儿营养需要对提高生猪生产效率和增加窝产仔猪初生重的整齐度具有重要意义。然而,母猪妊娠期间营养水平对仔猪初生重整齐度影响的报道很少。本文分析影响仔猪初生重差异的因素及其机制,旨在为寻找提高窝产仔猪整齐度的营养战略提供帮助。 | Campos P H Silva B A Donzele J L 陈琳 龚新明 李君荣 | 2012 | 养猪2012，，5： | 11 |
| 2 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 3 | Management of hepatitis C in patients with chronic kidney disease显示文摘Hepatitis C virus(HCV) infection is highly prevalent among chronic kidney disease(CKD) subjects under hemodialysis and in kidney transplantation(KT) recipients, being an important cause of morbidity and mortality in these patients. The vast majority of HCV chronic infections in the hemodialysis setting are currently attributable to nosocomial transmission. Acute and chronic hepatitis C exhibits distinct clinical and laboratorial features, which can impact on managementand treatment decisions. In hemodialysis subjects, acute infections are usually asymptomatic and anicteric; since spontaneous viral clearance is very uncommon in this context, acute infections should be treated as soon as possible. In KT recipients, the occurrence of acute hepatitis C can have a more severe course, with a rapid progression of liver fibrosis. In these patients, it is recommended to use pegylated interferon(PEG-IFN) in combination with ribavirin, with doses adjusted according to estimated glomerular filtration rate. There is no evidence suggesting that chronic hepatitis C exhibits a more aggressive course in CKD subjects under conservative management. In these subjects, indication of treatment with PEG-IFN plus ribavirin relies on the CKD stage, rate of progression of renal dysfunction and the possibility of a preemptive transplant. HCV infection has been associated with both liver disease-related deaths and cardiovascular mortality in hemodialysis patients. Among those individuals, low HCV viral loads and the phenomenon of intermittent HCV viremia are often observed, and sequential HCV RNA monitoring is needed. Despite the poor tolerability and suboptimal efficacy of antiviral therapy in CKD patients, many patients can achieve sustained virological response, which improve patient and graft outcomes. Hepatitis C eradication before KT theoretically improves survival and reduces the occurrence of chronic graft nephropathy, de novo glomerulonephritis and post-transplant diabetes mellitus. | Roberto J Carvalho-Filho Ana Cristina CA Feldner Antonio Eduardo B Silva Maria Lucia G Ferraz | 2015 | World Journal of Gastroenterology2015，21，2： | 4 |
| 4 | Perspectives on new biomarkers in gastric cancer: Diagnostic and prognostic applications显示文摘Gastric cancer is considered one of the most deadly tumors worldwide. Even with the decline in its incidence, the mortality rate of this disease has remained high, mainly due to its late diagnosis and to the lack of precise prognostic markers. The main purpose of this review is to present genetic, epigenetic and proteomic molecular markers that may be used in a diagnostic and prognostic manner and to discuss the pros and cons of each type of marker for improving clinical practice. In this sense, we observed that the use of genetic markers, especially mutations and polymorphisms, should be carefully considered, as they are strongly affected by ethnicity. Proteomic-based markers show promise, but the higher costs of the associated techniques con-tinue to make this approach expensive for routine use. Alternatively, epigenetic markers appear to be very promising, as they can be detected in bodily fluids as well as tissues. However, such markers must be used carefully because epigenetic changes may occur due to environmental factors and aging. Despite the advances in technology and its access, to date, there are few defined biomarkers of prognostic and diagnostic use for gastric tumors. Therefore, the use of a panel of several approaches(genetic, epigenetic and proteomic) should be considered the best alternative for clinical practice. | Danilo do Rosário Pinheiro Wallax Augusto Silva Ferreira Mariceli Baia Leo Barros Mariana Diniz Araújo Symara Rodrigues-Antunes Bárbara do Nascimento Borges | 2014 | World Journal of Gastroenterology2014，20，33： | 4 |
| 5 | Exploring the role of mononuclear phagocytes in the epididymis显示文摘精子在中央有免疫力的忍耐的建立以后带进 epididymis,没表明有免疫力的特权的一个机关,一十年或更多的外国抗原的猛攻提出唯一的生物挑战。历史上,到上皮的房间的一面紧交织的墙强制的 epididymal 小管的精子的物理监禁被认为足够足够阻止在配偶子和免疫系统之间并且,最终的生气谈话自体免疫的破坏。在鼠科的 epididymis 包括树枝状的房间和巨噬细胞的 mononuclear 吞噬细胞(MP ) 的复杂安排的发现建议我们可能在 posttesticular 环境低估了一个复杂 mucosal 免疫系统的存在。这评论在稳定的州的 epididymis 巩固我们 MP 的生理学的当前的知识并且由在在肠的 mucosa 对免疫系统被知道的上绘画在在 auto-antigenic 精子,病原体和免疫系统之间的可能的相互作用上推测。最终,进一步的调查将关于在 epididymis 由于自体免疫或煽动性的回答产生的病理的起源提供珍贵信息,包括附睾炎和不孕。 | Nicolas Da Silva Tegan B Smith | 2015 | Asian Journal of Andrology2015，17，4： | 3 |
| 6 | Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C显示文摘Sensory or motor peripheral neuropathy may be observed in a significant proportion of hepatitis C virus (HCV)-infected patients.However,central nervous system (CNS) involvement is uncommon,especially in cryoglobulin-negative subjects.We describe a case of peripheral neuropathy combined with an ischemic CNS event as primary manifestations of chronic HCV infection without cryoglobulinemia.Significant improvement was observed after antiviral therapy.We discuss the spectrum of neurological manifestations of HCV infection and review the literature. | Roberto J Carvalho-Filho Janaína Luz Narciso-Schiavon Luciano HL Tolentino Leonardo L Schiavon Maria Lucia G Ferraz Antonio Eduardo B Silva | 2012 | World Journal of Gastroenterology2012，18，2： | 3 |
| 7 | Acute fatty liver of pregnancy associated with severe acute pancreatitis:A case report显示文摘Acute fatty liver of pregnancy is a rare disease that affects women in the third trimester of pregnancy. Although infrequent, the disease can cause maternal mortality. The diagnosis is not always clear until the pregnancy is terminated, and significant complications, such as acute pancreatitis, can occur. Pancreatic involvement typically only occurs in severe cases after the development of hepatic and renal impairment. To date, little knowledge is available regarding how the disease causes pancreatitis. Treatment involves supportive measures and pregnancy interruption. In this report, we describe a case of a previously healthy 26-year-old woman at a gestational age of 27 wk and 6 d who was admitted with severe abdominal pain and vomiting. This case illustrates the clinical and laboratory overlap between acute fatty liver of pregnancy and pancreatitis, highlighting the difficulties in differentiating each disease. Furthermore, the hypothesis for this overlapping is presented, and the therapeutic options are discussed. | Cássio Vieira de Oliveira Alecsro Moreira Julio P Baima Leticia de C Franzoni Talles B Lima Fabio da S Yamashiro Kunie Yabuki Rabelo Coelho Ligia Y Sassaki Carlos Antonio Caramori Ferno G Romeiro Giovanni F Silva | 2014 | World Journal of Hepatology2014，6，7： | 3 |
| 8 | Fungal diversity notes 367-490:taxonomic and phylogenetic contributions to fungal taxa显示文摘This is a continuity of a series of taxonomic papers where materials are examined,described and novel combinations are proposed where necessary to improve our traditional species concepts and provide updates on their classification.In addition to extensive morphological descriptions and appropriate asexual and sexual connections,DNA sequence data are also analysed from concatenated datasets(rDNA,TEF-a,RBP2 and b-Tubulin)to infer phylogenetic relationships and substantiate systematic position of taxa within appropriate ranks.Wherever new species or combinations are being proposed,we apply an integrative approach(morphological and molecular data as well as ecological features wherever applicable).Notes on 125 fungal taxa are compiled in this paper,including eight new genera,101 new species,two new combinations,one neotype,four reference specimens,new host or distribution records for eight species and one alternative morphs.The new genera introduced in this paper are Alloarthopyrenia,Arundellina,Camarosporioides,Neomassaria,Neomassarina,Neotruncatella,Paracapsulospora and Pseudophaeosphaeria.The new species are Alfaria spartii,Alloarthopyrenia italica,Anthostomella ravenna,An.thailandica,Arthrinium paraphaeospermum,Arundellina typhae,Aspergillus koreanus,Asterina cynometrae,Bertiella ellipsoidea,Blastophorum aquaticum,Cainia globosa,Camarosporioides phragmitis,Ceramothyrium menglunense,Chaetosphaeronema achilleae,Chlamydotubeufia helicospora,Ciliochorella phanericola,Clavulinopsis aurantiaca,Colletotrichum insertae,Comoclathris italica,Coronophora myricoides,Cortinarius fulvescentoideus,Co.nymphatus,Co.pseudobulliardioides,Co.tenuifulvescens,Cunninghamella gigacellularis,Cyathus pyristriatus,Cytospora cotini,Dematiopleospora alliariae,De.cirsii,Diaporthe aseana,Di.garethjonesii,Distoseptispora multiseptata,Dis.tectonae,Dis.tectonigena,Dothiora buxi,Emericellopsis persica,Gloniopsis calami,Helicoma guttulatum,Helvella floriforma,H.oblongispora,Hermatomyces subiculosa,Juncaceicola italica,Lactarius dirkii,Lentithecium unicellulare,Le.voraginesporum,Leptosphaeria cirsii,Leptosphaeria irregularis,Leptospora galii,Le.thailandica,Lindgomyces pseudomadisonensis,Lophiotrema bambusae,Lo.fallopiae,Meliola citri-maximae,Minimelanolocus submersus,Montagnula cirsii,Mortierella fluviae,Muriphaeosphaeria ambrosiae,Neodidymelliopsis ranunculi,Neomassaria fabacearum,Neomassarina thailandica,Neomicrosphaeropsis cytisi,Neo.cytisinus,Neo.minima,Neopestalotiopsis cocoe¨s,Neopestalotiopsis musae,Neoroussoella lenispora,Neotorula submersa,Neotruncatella endophytica,Nodulosphaeria italica,Occultibambusa aquatica,Oc.chiangraiensis,Ophiocordyceps hemisphaerica,Op.lacrimoidis,Paracapsulospora metroxyli,Pestalotiopsis sequoiae,Peziza fruticosa,Pleurotrema thailandica,Poaceicola arundinis,Polyporus mangshanensis,Pseudocoleophoma typhicola,Pseudodictyosporium thailandica,Pseudophaeosphaeria rubi,Purpureocillium sodanum,Ramariopsis atlantica,Rhodocybe griseoaurantia,Rh.indica,Rh.luteobrunnea,Russula indoalba,Ru.pseudoamoenicolor,Sporidesmium aquaticivaginatum,Sp.olivaceoconidium,Sp.pyriformatum,Stagonospora forlicesenensis,Stagonosporopsis centaureae,Terriera thailandica,Tremateia arundicola,Tr.guiyangensis,Trichomerium bambusae,Tubeufia hyalospora,Tu.roseohelicospora and Wojnowicia italica.New combinations are given for Hermatomyces mirum and Pallidocercospora thailandica.A neotype is proposed for Cortinarius fulvescens.Reference specimens are given for Aquaphila albicans,Leptospora rubella,Platychora ulmi and Meliola pseudosasae,while new host or distribution records are provided for Diaporthe eres,Di.siamensis,Di.foeniculina,Dothiorella iranica,Do.sarmentorum,Do.vidmadera,Helvella tinta and Vaginatispora fuckelii,with full taxonomic details.An asexual state is also reported for the first time in Neoacanthostigma septoconstrictum.This paper contributes to a more comprehensive update and improved identification of many ascomycetes and basiodiomycetes. | Kevin D.Hyde Sinang Hongsanan Rajesh Jeewon D.Jayarama Bhat Eric H.C.McKenzie E.B.Gareth Jones Rungtiwa Phookamsak Hiran A.Ariyawansa Saranyaphat Boonmee Qi Zhao Faten Awad Abdel-Aziz Mohamed A.Abdel-Wahab Supharat Banmai Putarak Chomnunti Bao-Kai Cui Dinushani A.Daranagama Kanad Das Monika C.Dayarathne Nimali Ide Silva Asha J.Dissanayake Mingkwan Doilom Anusha H.Ekanayaka Tatiana Baptista Gibertoni Aristóteles Góes-Neto Shi-Ke Huang Subashini C.Jayasiri Ruvishika S.Jayawardena Sirinapa Konta Hyang Burm Lee Wen-Jing Li Chuan-Gen Lin Jian-Kui Liu Yong-Zhong Lu Zong-Long Luo Ishara S.Manawasinghe Patinjareveettil Manimohan Ausana Mapook Tuula Niskanen Chada Norphanphoun Moslem Papizadeh Rekhani H.Perera Chayanard Phukhamsakda Christian Richter AndréL.C.Mde A.Santiago E.Ricardo Drechsler-Santos Indunil C.Senanayake Kazuaki Tanaka T.M.D.S.Tennakoon Kasun M.Thambugala Qing Tian Saowaluck Tibpromma Benjarong Thongbai Alfredo Vizzini Dhanushka N.Wanasinghe Nalin N.Wijayawardene Hai-Xia Wu Jing Yang Xiang-Yu Zeng Huang Zhang Jin-Feng Zhang Timur S.Bulgakov Erio Camporesi Ali H.Bahkali Mohammad A.Amoozegar Lidia Silva Araujo-Neta Joseph F.Ammirati Abhishek Baghela R.P.Bhatt Dimitar Bojantchev Bart Buyck Gladstone Alves da Silva Catarina Letícia Ferreira de Lima Rafael JoséVilela de Oliveira Carlos Alberto Fragoso de Souza Yu-Cheng Dai Bálint Dima Tham Thi Duong Enrico Ercole Fernando Mafalda-Freire Aniket Ghosh Akira Hashimoto Sutakorn Kamolhan Ji-Chuan Kang Samantha C.Karunarathna Paul M.Kirk Ilkka Kytovuori Angela Lantieri Kare Liimatainen Zuo-Yi Liu Xing-Zhong Liu Robert Lücking Gianfranco Medardi Peter E.Mortimer Thi Thuong Thuong Nguyen Itthayakorn Promputtha K.N.Anil Raj Mateus A.Reck Saisamorn Lumyong Seyed Abolhassan Shahzadeh-Fazeli Marc Stadler Mohammad Reza Soudi Hong-Yan Su Takumasa Takahashi Narumon Tangthirasunun Priyanka Uniyal Yong Wang Ting-Chi Wen Jian-Chu Xu Zhong-Kai Zhang Yong-Chang Zhao Jun-Liang Zhou Lin Zhu | 2016 | Fungal Diversity2016，，5： | 2 |
| 9 | Extramedullary plasmocytoma associated with a massive deposit of amyloid in the duodenum显示文摘We report a rare case of extramedullary plasmocytoma associated with a massive deposit of amyloid in the duodenum.A 72-year-old Japanese man was admitted to our hospital presenting with a 3-mo history of epigastric pain, vomiting and weight loss.On computed tomography(CT) a wall thickening of the fourth part of the duodenum was observed.Multiple biopsies obtained from the lesion showed inflltration of plasma cells and lymphocytes, but they were not conclusive.The patient underwent resection of the lesion and, on histopathological examination, the lesion consisted of a dense and diffuse inflltrate of plasma cells and a few admixed lymphocytes with reactive follicles extending to the muscular propria.An extensive deposition of amyloid was also observed.Immunohistochemical stains revealed that a few plasmacytoid cells showed λ light chain staining, though most were κ light chain positive.These cells also were positive for CD138 and CD56 but negative for CD20 and CD79.The flndings were consistent with extramedullary plasmocytomaassociated with a massive deposit of amyloid in duodenum.A subsequent workup for multiple myeloma was completely negative.The patient showed no signs of local recurrence or dissemination of the disease after 12 mo follow-up.Because of the association of plasmocytoma and amyloidosis, the patient must be followed up because of the possible systemic involvement of the neoplasm and amyloidosis in future. | Fabiana Pirani Carneiro Maria de Nazareth Machado Sobreira Lívia Bravo Maia Alesso Cervantes Sartorelli Luiz Eduardo de Almeida Prado Franceschi Mauro Brito Brando Bárbara Wosnjuk Calaca Fernando Silva Lustosa Joo Vieira Lopes | 2009 | World Journal of Gastroenterology2009，15，28： | 2 |
| 10 | Grain-size end-members and environmentally sensitive grain-size components: A comparative study in the mud shelf depocenters off southern Brazil显示文摘The current study aims to do a comparative analysis of the results obtained with two End-Member(EM)grain-size modeling techniques(AnalySize and BasEMMA)and the Environmental Sensitive Grain-Size(ESGS)modeling for sediment samples collected in the mudbelts of the southern Brazilian shelf.The methods were compared using grain-size data from the south Brazilian shelf,and the results are discussed here.It is the first time that the concept of ESGS,in its present form,is utilized outside China.The results show that despite its relative ease of use,the ESGS is not fully comparable to the EM analyses,and only two grain-size ESGS classes were recognized as analogous to EMs.The comparison of the AnalySize and BasEMMA procedures also revealed significant differences between the techniques.A comparative analysis between the two EM techniques revealed advantages in the BasEMMA,especially in the better correlation of the end-members with the original grain size distribution.The analysis of the geographical distribution of the EM abundances allowed point sources of sandy populations to be recognized as well as the contribution of the Rio de la Plata as a source of silty sediments to be inferred. | Michel Michaelovitch de Mahiques Samara Cazzoli y Goya Maria Carolina da Silva Nogueira de Matos Rodrigo Augusto Udenal de Oliveira Bianca Sung Mi Kim Paulo Alves de Lima Ferreira Rubens Cesar Lopes Figueira Marcia Caruso Bícego | 2021 | International Journal of Sediment Research2021，36，2： | 2 |
| 11 | The corpus cavernosum after treatment with dutasteride or finasteride: a histomorphometric study in a benign prostatic hyperplasia rodent model显示文摘 | Marcello H A Da Silva Waldemar S Costa Francisco J B Sampaio Diogo B De Souza | 2018 | Asian Journal of Andrology2018，20，5： | 2 |
| 12 | Identification and Characterization of Murine Cytotoxie T Cells that Kill Mycobaeterium Tuberculosis显示文摘 | Silva C L Lowrie D B | 2000 | Infect Immune2000，68，6： | 1 |
| 13 | Chitosan-based femimagnetic membrane显示文摘 | M A Mace^do M N B Silva A R Cestari | 2004 | Physica B2004，，354： | 1 |
| 14 | A global geometric framework for nonlinear dimensionality reduction显示文摘 | Tenenbanm J B De Silva V and Langford J C | 2000 | Science2000，290，5500： | 1 |
| 15 | Sulphate removal from industrial wastewater using a packed-bed anaerobic reactor显示文摘 | Silva A J Varesche M B Foresti E | 2002 | Process Biochem2002，37，9： | 1 |
| 16 | Determination of Lead in Biological Samples by High-resolution Continuum Source Graphite Furnace Atomic Absorption Spectrometry with Direct Solid Sampling显示文摘 | BORGES D G DA SILVA A F WELZ B | 2006 | JAnal at Spectrom2006，21，： | 1 |
| 17 | A Global Geometric Framework for Nonlinear Dimensionality Reduction 显示文摘 | Tenengaum J B De Silva V Langford J C | 2000 | Science2000，290，5500： | 1 |
| 18 | A Global Geometric Framework for Nonlinear Dimensionality Reduction显示文摘 | Tenenbaum J B Silva V Langford J C | 2000 | Science2000，290，5500： | 1 |
| 19 | Potassium permanganate oxidation of phenanthrene and pyrene in contaminated soils显示文摘 | Silva P T de souza e Silva V L Neto B B | 2009 | Journal of Hazardous Materials2009，168，： | 1 |
| 20 | 293 cell cycle synchronisation adenovirus vector production显示文摘 | Ferreira T B Perdigao R Silva A C | 2009 | Biotechnol Prog2009，25，1： | 1 |
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