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| 1 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 2 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 3 | Efficacy of pancreatoscopy for pancreatic duct stones:A systematic review and meta-analysis显示文摘BACKGROUND Pancreatic duct stones can lead to significant abdominal pain for patients.Per oral pancreatoscopy(POP)-guided intracorporal lithotripsy is being increasingly used for the management of main pancreatic duct calculi(PDC)in chronic pancreatitis.POP uses two techniques:Electrohydraulic lithotripsy(EHL)and laser lithotripsy(LL).Data on the safety and efficacy are limited for this procedure.We performed a systematic review and meta-analysis with a primary aim to calculate the pooled technical and clinical success rates of POP.The secondary aim was to assess pooled rates of technical success,clinical success for the two individual techniques,and adverse event rates.AIM To perform a systematic review and meta-analysis of POP,EHL and LL for management of PDC in chronic pancreatitis.METHODS We conducted a comprehensive search of multiple electronic databases and conference proceedings including PubMed,EMBASE,Cochrane,Google Scholar and Web of Science databases(from 1999 to October 2019)to identify studies with patient age greater than 17 and any gender that reported on outcomes of POP,EHL and LL.The primary outcome assessed involved the pooled technical success and clinical success rate of POP.The secondary outcome included the pooled technical success and clinical success rate for EHL and LL.We also assessed the pooled rate of adverse events for POP,EHL and LL including a subgroup analysis for the rate of adverse event subtypes for POP:Hemorrhage,post-endoscopic retrograde cholangiopancreatography pancreatitis(PEP),perforation,abdominal pain,fever and infections.Technical success was defined as the rate of clearing pancreatic duct stones and clinical success as the improvement in pain.Randomeffects model was used for analysis.Heterogeneity between study-specific estimates was calculated using the Cochran Q statistical test and I2 statistics.Publication bias was ascertained,qualitatively by visual inspection of funnel plot and quantitatively by the Egger test.RESULTS A total of 16 studies including 383 patients met the inclusion criteria.The technical success rate of POP was 76.4%(95%CI:65.9-84.5;I2=64%)and clinical success rate was 76.8%(95%CI:65.2-85.4;I2=66%).The technical success rate of EHL was 70.3%(95%CI:57.8-80.3;I2=36%)and clinical success rate of EHL was 66.5%(95%CI:55.2-76.2;I2=19%).The technical success rate of LL was 89.3%(95%CI:70.5-96.7;I2=70%)and clinical success rate of LL was 88.2%(95%CI:66.4-96.6;I2=77%).The incidence of pooled adverse events for POP was 14.9%(95%CI:9.2-23.2;I2=49%),for EHL was 11.2%(95%CI:5.9-20.3;I2=15%)and for LL was 13.1%(95%CI:6.3-25.4;I2=31%).Subgroup analysis of adverse events showed rates of PEP at 7%(95%CI:3.5-13.6;I2=38%),fever at 3.7%(95%CI:2-6.9;I2=0),abdominal pain at 4.7%(95%CI:2.7-7.8;I2=0),perforation at 4.3%(95%CI:2.1-8.4;I2=0),hemorrhage at 3.4%(95%CI:1.7-6.6;I2=0)and no mortality.There was evidence of publication bias based on funnel plot analysis and Egger’s test.CONCLUSION Our study highlights the high technical and clinical success rates for POP,EHL and LL.POP-guided lithotripsy could be a viable option for management of chronic pancreatitis with PDC. | Syed M Saghir Harmeet S Mashiana Babu P Mohan Banreet S Dhindsa Amaninder Dhaliwal Saurabh Chandan Neil Bhogal Ishfaq Bhat Shailender Singh Douglas G Adler | 2020 | World Journal of Gastroenterology2020，26，34： | 5 |
| 4 | A new technique for the analysis of self-excited induction generator显示文摘 | SINGH S P JAIN M P | 1995 | Electric Machine and Power Systems1995，23，： | 2 |
| 5 | A simple technique for quantitation of low levels of DNA damage in individual cells 显示文摘 | Singh N P Mccoy M T Tice R R | 1988 | Experimental Cell Research1988，175，： | 2 |
| 6 | Efficacy of phosphate carriers as foliar fertilizer on rainfed upland cotton (Gossypium hirsitum)显示文摘 | VENUGOPLAN M V TARHALHAR P P SINGH J | 1995 | Indian J Agri Sci1995，65，： | 1 |
| 7 | A simple technique for quantification of low levels of DNA damage in individual cells显示文摘 | SINGH N P MCCOY M T TICE R R | 1988 | Exp Cell Res1988，175，1： | 1 |
| 8 | A simple tech- nique for quantitation of low levels of DNA damage in indi-vidual cells 显示文摘 | Singh N P McCoy M T Tice R R et d | 1988 | Experimental Cell Research1988，175，1： | 1 |
| 9 | Input-output invertibility and sliding mode control for close formation flying of multiple UAVs显示文摘 | SINGH S N PACHTER M CHANDLER P | 2000 | Int J Robust Nonlinear Con- trol2000，，10： | 1 |
| 10 | Biodegradable delivery system for a birth control vaccine:immunogenicity studies in rats and monkeys显示文摘 | Singh M Singh O Talwar G P | 1995 | Pharm Res1995，12，： | 1 |
| 11 | Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms显示文摘 | Singh P K Schaefer A L Parsek M R | 2000 | Nature2000，407，6805： | 1 |
| 12 | Active metal brazing and characterization of brazed joints in titanium to carbon-carbon composites显示文摘 | SINGH M SHPARGEL T P MORSCHER G N | 2005 | Materials Science and Engineering2005，412，： | 1 |
| 13 | Energy-efficient homo- geneous clustering algorithm for wireless sensor network 显示文摘 | Singh S K Singh M P Singla D K | 2010 | International Journal of Wireless & Mobile Net- works2010，2，3： | 1 |
| 14 | Bridging endom-etrial receptivity and implantation: network of hor-mones, cytokines, and growth factors 显示文摘 | Singh M Chaudhry P Asselin E | 2011 | J En-docrinol2011，210，1： | 1 |
| 15 | Brazing ofcarbon-carbon composites to Cu-clad molybdenum forthermal management applications 显示文摘 | SINGH M ASTHANA R SHPARGEL T P | 2007 | Materials Scienceand Engineering2007，，： | 1 |
| 16 | Effect of Nanoparticles on the Magnetic Properties of Mn-Zn Soft Ferrite显示文摘 | Mathura P Thakur A Singh M | 2008 | Journal of Magnetism and MagneticMaxerials2008，320，10： | 1 |
| 17 | Seismic analysis and design with maxwell dampers 显示文摘 | Singh M P Verm N P Moreschi L M | 2003 | Journal of Engineering Mechanics2003，129，3： | 1 |
| 18 | ExtraceUular xyla- nase production by Pleurotus species on lignocellulosic wastes under in vivo condition using novel pretreatment显示文摘 | Singh M P Pandey A K Vishwakarma S K | 2012 | Cellular and Molecu- lar Biology2012，58，1： | 1 |
| 19 | Effects of tranexamic acid on blood loss during total hip arth- roplasty 显示文摘 | Singh J Ballal M S Mitchell P | 2010 | Journal of orthopaedic surgery ( Hong Kong)2010，18，3： | 1 |
| 20 | Effects of sewage sludge amendment on heavy metal accumulation and consequent responses of Beta vulgaris plants 显示文摘 | Singh R P Agrawal M | 2007 | Chemosphere2007，67，11： | 1 |
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