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| 1 | Heart-type fatty acid binding protein (H-FABP) as a biomarker for acute myocardial injury and long-term post-ischemic prognosis显示文摘尖锐心肌的梗塞(AMI ) 是一个威胁生活的事件。甚至与及时处理,尖锐 ischemic 心肌的损害和随后的局部缺血灌注损害(IRI ) 能仍然是困难的问题处理。除了放射学并且另外的辅助考试,适用的心脏的 biomarkers 的实验室测试为这混乱监视的早诊断和结束也是必要的。心类型丰满的酸绑定蛋白质(H-FABP ) 主要在 cardiomyocytes 内存在,最近为心肌的损害作为潜在地有希望的 biomarker 出现了。在这评论,我们在对心肌的损害和 IRI 的评价讨论 H-FABP 的敏感和特性,特别在早阶段,和它与另外的通常使用的心脏的 biomarkers 比较的长期的预示的价值,包括肌球素( Mb ),心脏的 troponin 我( cTnI ),肌酸 kinase MB ( CK-MB ),C反应的蛋白质( CRP ),肝糖 phosphorylase isoenzyme BB ( GPBB ),和高敏感的心脏的 troponin T ( hs-cTnT )。有另外的 biomarkers 的 H-FABP 的联合申请的潜力和值也被讨论。最后, H-FABP 的前景被总结;几个技术问题被讨论在临床的实践便于 H-FABP 的更宽的申请。 | Xiao-dong YE Yi HE Sheng WANG Gordon T WONG Michael G IRWIN Zhengyuan XIA | 2018 | Acta Pharmacologica Sinica2018，39，7： | 72 |
| 2 | Yes相关蛋白通过肿瘤坏死因子受体相关因子6控制内皮活化和血管炎症显示文摘继发于异常的内皮激活的微血管炎症和内皮功能障碍在败血症和器官衰竭的病理生理学中起关键作用。抑制内皮细胞过度活化的内在信号传导机制尚未完全明了。该研究旨在确定Yes相关蛋白(Yes-associated protein,YAP)(Hippo通路的主要转录共激活剂)在调节内皮活化和血管炎症的强度和程度中的中心作用。 | 刘青 叶鹏 Lv Y Kim K Sheng Y Cho J Qain Z Zhao YY Hu G Pan D Malik AB | 2018 | 中华高血压杂志2018，26，8： | 20 |
| 3 | Molecular organic geochemical evidence for paleoenvironmental changes at 11.87—12.28 m in GS-1 sedimentary core,Gucheng Lake,East China显示文摘Organic lipids with different occurrence modes in a sedimentary core in a subtropicalfreshwater lake, Gucheng Lake, were sequentially extracted, separated and analyzed. Thedown-core variations of OEP index of alkanes, C18:2/C18:0 ratios of fatty acids, ratios of boundfatty acids to free fatty acids, thermo-maturity indices of hopanoid hydrocarbons and relativeconcentrations of sedimentary minerals revealed an evident increasing in allochthonous inputfrom rock detritus below 12.28 m in the sedimentary profile. The distribution pattern of tightly-bound β-hydroxy fatty acids indicated a difference in bacterial communities above and below theboundary, as well as the gammacerane index may assign a significant change in lake watersalinity. The evidence, in general, suggested that a significant paleoenvironmental change hadtaken place in ca. 9.6 kaBP on the regional basis. | Zhang, G Sheng, GY Fu, JM Wang, SM | 1999 | Chinese Science Bulletin1999，44，15： | 15 |
| 4 | Co-effect of Demand-control-support Model and Effort-reward Imbalance Model on Depression Risk Estimation in Humans: Findings from Henan Province of China显示文摘Objective To investigate the co-effect of Demand-control-support(DCS) model and Effort-reward Imbalance(ERI) model on the risk estimation of depression in humans in comparison with the effects when they are used respectively. Methods A total of 3 632 males and 1 706 females from 13 factories and companies in Henan province were recruited in this cross-sectional study. Perceived job stress was evaluated with the Job Content Questionnaire and Effort-Reward Imbalance Questionnaire(Chinese version). Depressive symptoms were assessed by using the Center for Epidemiological Studies Depression Scale(CES-D). Results DC(demands/job control ratio) and ERI were shown to be independently associated with depressive symptoms. The outcome of low social support and overcommitment were similar. High DC and low social support(SS), high ERI and high overcommitment, and high DC and high ERI posed greater risks of depressive symptoms than each of them did alone.ERI model and SS model seem to be effective in estimating the risk of depressive symptoms if they are used respectively. Conclusion The DC had better performance when it was used in combination with low SS. The effect on physical demands was better than on psychological demands. The combination of DCS and ERI models could improve the risk estimate of depressive symptoms in humans. | YU Shan Fa NAKATA Akinori GU Gui Zhen SWANSON Naomi G ZHOU Wen Hui HE Li Hua WANG Sheng | 2013 | Biomedical and Environmental Sciences2013，26，12： | 8 |
| 5 | Optical implementation of image encryption using random-phase encoding显示文摘 | NETO L G SHENG Y L | 1996 | Opt Eng1996，35，9： | 4 |
| 6 | Seasonal variation of solvent extractable organic compounds in the aerosols in Qingdao, China显示文摘 | Guo Z G Sheng L F Feng J L | 2003 | Atmospheric Environment2003，37，13： | 1 |
| 7 | Characterization of extracellular polymeric substances of aerobic and anaerobic sludge using three- dimensional excitation and emission matrix fluorescence spectroscopy 显示文摘 | Sheng G P Yu H Q | 2006 | Water Research2006，40，6： | 1 |
| 8 | Clinical significance and prognostic value of serum Dickkopf-1 concentrations in patients with lung cancer显示文摘 | SHENG S L HUANG G YU B | 2009 | Clin Chem2009，55，9： | 1 |
| 9 | Ruthenium-iron-catalyzed oxidation of an immature asphaltene: Structural features and biomarker distribution显示文摘 | Peng P Fu J Sheng G | 1999 | Energy and Fuel1999，13，2： | 1 |
| 10 | Evidence of aerobic denitrification显示文摘 | Ding A Z Fu J M Sheng G Y | 2000 | Chin Scie Bull2000，45，3： | 1 |
| 11 | Development of time-resolved immunofluorometric assays for CA 72-4 and application in sera of patients with gastric tumors显示文摘 | Sheng SL Wang Q Huang G | 2007 | Clin Chim Acta2007，380，12： | 1 |
| 12 | Evidence of aerobicdenitrification 显示文摘 | Ding A Z Fu M Sheng G Y | 2000 | Chin Scie Bull2000，45，3： | 1 |
| 13 | Development of time-re- solved immunofluorometric assays for vascular endothelial growth factor and application on plasma of patients with gastric tumours 显示文摘 | Sheng SL Bao SH Huang G | 2008 | Clin Exp Immunol2008，151，3： | 1 |
| 14 | Seasonal variation of solvent extractable organic compounds in the aerosols in Qingdao, China显示文摘 | Guo Z G Sheng L F Feng J L | 2003 | Atmospheric Environment2003，37，13： | 1 |
| 15 | Molecular marker study of extractable organic matter in aerosols from urban areas of China 显示文摘 | Simoneit B R T Sheng G Chen X | 1991 | Atmospheric Environment1991，25，10： | 1 |
| 16 | Enhanced pesticide sorption by soils containing particulate matter from crop residue burns显示文摘 | Yang Y Sheng G Y | 2003 | Environl Sci Technol2003，37，16： | 1 |
| 17 | Relation of organic contaminant equilibrium sorption and kinetic uptake in plants 显示文摘 | Li H Sheng G Y Chiou C T | 2005 | Environmental Science and Technology2005，39，： | 1 |
| 18 | The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs:a meta-analysis显示文摘 | Sheng YJ Wu G He HY | 2014 | Infect Genet Evol2014，24，： | 1 |
| 19 | The combination use of pla- telet-rich fibrin and treated dentin matrix for tooth root rege-neration by cell homing显示文摘 | Ji B Sheng L Chen G | 2015 | Tissue Eng Part A2015，21，12： | 1 |
| 20 | Enhanced removal of uranium(V I)b y nanoscale zerovalent iron supported onNa - bentonite and an investigation of mechanism显示文摘 | Sheng G Shao X L i Y e t a l | 2014 | The Journal of Physical Chemistry A2014，118，16： | 1 |
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