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| 1 | The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline显示文摘 | Gaspar LE Mehta MP Patchell RA Burri SH Robinson PD Morris RE Ammirati M Andrews DW Asher AL Cobbs CS Kondziolka D Linskey ME Loeffler JS McDermott M Mikkelsen T Olson JJ Paleologos NA Ryken TC Kalkanis SN. | 2010 | 中国神经肿瘤杂志2010，8，1： | 98 |
| 2 | 重组脊髓灰质炎病毒用于治疗复发胶质母细胞瘤(英文)显示文摘Background The prognosis of patients with recurrent World Health Organization(WHO)grade IV malignant glioma is dismal,and there is currently no effective therapy.We conducted a dose-finding and toxicity study in this population of patients,evaluating convection-enhanced,intratumoral delivery of the recombinant nonpathogenic polio-rhinovirus chimera(PVSRIPO).PVSRIPO recognizes the poliovirus receptor CD155,which is widely expressed in neoplastic cells of solid tumors and in major components of the tumor microenvironment.Methods We enrolled consecutive adult patients who had recurrent supratentorial WHO grade IV malignant glioma,confirmed on histopathological testing,with measurable disease(contrast-enhancing tumor of≥1 cm and≤5.5 cm in the greatest dimension).The study evaluated seven doses,ranging between 107 and 1010 50%tissue-culture infectious doses(TCID50),first in a dose-escalation phase and then in a dose-expansion phase.Results From May 2012 through May 2017,a total of 61 patients were enrolled and received a dose of PVSRIPO.Dose level-1(5.0×107TCID50)was identified as the phase 2 dose.One dose-limiting toxic effect was observed;a patient in whom dose level 5(1010TCID50)was administered had a grade 4 intracranial hemorrhage immediately after the catheter was removed.To mitigate locoregional inflammation of the infused tumor with prolonged glucocorticoid use,dose level 5 was deescalated to reach the phase 2 dose.In the dose-expansion phase,19%of the patients had a PVSRIPO-related adverse event of grade 3 or higher.Overall survival among the patients who received PVSRIPO reached a plateau of 21%(95%confidence interval,11 to 33)at 24 months that was sustained at 36 months.Conclusions Intratumoral infusion of PVSRIPO in patients with recurrent WHO grade IV malignant glioma confirmed the absence of neurovirulent potential.The survival rate among patients who receivedPVSRIPO immunotherapy was higher at 24 and 36 months than the rate among historical controls. | Desjardins A Gromeier M Herndon JE 2nd Beaubier N Bolognesi DP Friedman AH Friedman HS McSherry F Muscat AM Nair S Peters KB Randazzo D Sampson JH Vlahovic G Harrison WT McLendon RE Ashley D Bigner DD | 2018 | 中华神经外科疾病研究杂志2018，17，4： | 2 |
| 3 | Visualization of 11C-Flumitrazepan displacement in the brain of live baboon显示文摘 | Comar D Mazière M Codot JM | 1979 | Nature1979，280，5720： | 1 |
| 4 | Intercellular adhesion molecule expression in the evolving human cutaneous delayed hypersensitivity reaction 显示文摘 | Lewis RE Buchsbaum M Whitaker D | 1989 | J Invest Dermatol1989，93，5： | 1 |
| 5 | Lycopene inhibits NF-KB-me- diated IL-8 expression and changes redox and PPAR gamma signal ling in cigarette smoke-stimulated macrophages显示文摘 | Simonc RE Russo M Catalano A et d | 2011 | PLoS One2011，6，19： | 1 |
| 6 | Appendicular skeletal muscle mass:effects of age,gender,and ethnicity显示文摘 | Gallagher D Visser M De Meersman RE | 1997 | J Appl Physiol1997，83，1： | 1 |
| 7 | Proposed international clinical diabetic retinopathy and diabetie macular edema disease severity scales 显示文摘 | Wilkinson C P Ferris FL 3 rd Klein RE Lee PP Agardh C D Davision M | 2003 | Ophthalmology2003，110，9： | 1 |
| 8 | jnter-cellular adhesion molecule expression in theevolving human cutaneous delayed liypersen-sitivity reaction 显示文摘 | Lewis RE Buchsbaum M Whitaker D | 1989 | Invest Dermatol1989，93，5： | 1 |
| 9 | QIIME allows analysis of high-throughput community sequencing data 显示文摘 | Caporaso JG Kuczynski J Stombaugh J Bittinger K Bushman FD Costello EK Fierer N Pena AG Goodrich JK Gordon JI Huttley GA Kelley ST Knights D Koenig JE Ley RE Lozupone CA Mcdonald D Muegge BD Pirrung M Reeder J Sevinsky JR Tumbaugh PJ Walters WA Widmann J Yatsunenko T Zaneveld J Knight R | 2010 | Nat Methods2010，7，5： | 1 |
| 10 | Intercellalar adhesion molecule expression in the evolving human cutaneous delayed hyporsensitivity reaction显示文摘 | Lewis RE Buchsbanm M Whitakor D | 1989 | J Invest Dermatol1989，93，5： | 1 |
| 11 | ERole of matrix metalloproteinase in the pathogenesis of multiple sclerosis] 显示文摘 | Kurzepa J Bartosik Psujek H Suchozebrska Jesionek D Re jdak K Stryjecka-Zimmer M Stelmasiak Z | 2005 | Neurol Neurochir Pol2005，39，： | 1 |
| 12 | The chronic illness resources survey: cross -validation and sensitivity to intervention显示文摘 | Glasgow RE Toobert D J Barrera Jr M | 2005 | Health Educ Res2005，20，4： | 1 |
| 13 | Ascochyta blight of chickpea in Australia identification pathogenicity and mating type 显示文摘 | Khan M S A Ramsey M D Corbi~re R | 1999 | Plant Pathol1999，48，2： | 1 |
| 14 | Electrodeposition of Cu from acidic sulphate solutions containing cetyhrimethyl- ammonium bromide (CTAB) 显示文摘 | Benedetto B D' Urzo L Re M | 2008 | Journal of Applied Electrochemistry2008，38，： | 1 |
| 15 | Genome sequence of Streptococcus mutans UA159,a cariogenic dental pathogen显示文摘 | Ajdic D McShan WM M cLaughin RE | 2002 | Proc Natl Acad SciUSA2002，99，14： | 1 |
| 16 | A case of ACTH-independent bilateralmacronodular adrenal hyperplasia and severe congestive heart failure显示文摘 | Suri D Alonso M Weiss RE | 2006 | J Endocrinol Invest2006，29，10： | 1 |
| 17 | Immobilized Rh,Ru,Pd and Ni complexes as catalysts in the hydrogenation of cyclohexene显示文摘 | CAGNOLA E A QUIROGA M E LIPRANDI D A L'ARGENTIRE P C | 2004 | Appl Catal A2004，274，12： | 1 |
| 18 | A rapid procedure for the isolation of Cot-1 DNA from plants显示文摘 | Zwick M S Hanson RE Mcknight T D | 1997 | Genome1997，40，2： | 1 |
| 19 | Transcriptional repression of protein kinase C alpha via Spl by wild type p53 is involved in inhibition of multidrug resistance 1 P-glycoprotein phosphorylation 显示文摘 | Zhan M Yu D Liu J Glazer RI Hannay J Pollock RE | 2005 | J Biol Chem2005，280，6： | 1 |
| 20 | Analysis of 1-year clinical outcomes in the SIRIUS trial: a randomized trial of a sirolimus-eluting stent versus a standard stent in patients at high risk for coronary restenosis显示文摘 | Holmes DR Jr Leon MB Moses JW Popma JJ Cutlip D Fitzgerald PJ Brown C Fischell T Wong SC Midei M Snead D Kuntz RE | 2004 | Circulation2004，109，5： | 1 |
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