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1068篇 您的检索式:作者名="Randolph M"
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1Augmenting peripheral nerve regeneration using stem cells: A review of current opinion显示文摘Outcomes following peripheral nerve injury remain frustratingly poor. The reasons for this are multifactorial, although maintaining a growth permissive environment in the distal nerve stump following repair is arguably the most important. The optimal environment for axonal regeneration relies on the synthesis and release of many biochemical mediators that are temporally and spatially regulated with a high level of incompletely understood complexity. The Schwann cell(SC) has emerged as a key player in this process. Prolonged periods of distal nerve stump denervation, characteristic of large gaps and proximal injuries, have been associated with a reduction in SC number and ability to support regenerating axons. Cell based therapy offers a potential therapy for the improvement of outcomes following peripheral nerve reconstruction. Stem cells have the potential to increase the number of SCs and prolong their ability to support regeneration. They may also have the ability to rescue and replenish populations of chromatolytic and apoptotic neurons following axotomy. Finally, they can be used in non-physiologic ways to preserve injured tissues such as denervated muscle while neuronal ingrowth has not yet occurred. Aside from stem cell type, careful consideration must be given to differentiation status, how stem cells are supported following transplantation and how they will be delivered to the site of injury. It is the aim of this article to review current opinions on the strategies of stem cell based therapy for the augmentation of peripheral nerve regeneration.Neil G Fairbairn Amanda M Meppelink Joanna Ng-Glazier Mark A Randolph Jonathan M Winograd 2015World Journal of Stem Cells2015,7,1:12
2Analytical modeling of hammer impact for pile driving显示文摘Deeks A J Randolph M F 1993International Journal for Numerical and Analytical Methods in Geomechanics1993,17,5:2
3Analytical solution for pile hammer impact 显示文摘Take W A Valsangkar A J Randolph M F 1999Computers and Geotechnics1999,25,2:2
4Driven pile in clay the effect of installation and subsequent consolidation显示文摘Randolph M F Carter J P Wroth C P 1979Geotechnique1979,29,4:2
5Driven Piles in clay - the effects of installation and subsequent consolidation显示文摘RANDOLPH M F CARTER J P WROTH C P 1979Geotechnique1979,29,4:1
6Sub-micrometer-sized biodegradable particles of poly(L-lactic acid) via the gas antisolvent spray precipitation process 显示文摘RANDOLPH T W RANDOLPH A D MEBES M 1993Biotechnology Progress1993,23,9:1
7Numerical analysis of T-bar penetration in soft clay显示文摘RANDOLPH M F ANDERSEN K H 2006International Journal of Geomcehanics American Society of Civil Engineers2006,6,6:1
8Chemical and cultural control of the sunflower moth in Texas显示文摘Teetes G L Randolph N M 1969J Econ Entomol1969,62,:1
9Effect of strength non-homogeneity on the shape of failure envelopes for combined loading of strip and circular foundations on clay 显示文摘Gourvenec S Randolph M F 2003Geotechnique2003,53,6:1
10Grafting of polypropylene with N-cyclohexylmaleimide and styrene simultaneously using supercritical CO2显示文摘 Blanch H W Pransnitz J M 1988AICHE Journal1988,34,7:1
11Combined loading of skirted foundations显示文摘Bransby M F Randolph M F 1998Geotechnique1998,48,5:1
12Driven piles in clay-the effects of installation and sub- sequent consolidation显示文摘RANDOLPH M F CARTER J P & WROTH C P 1979Geotechnique1979,29,4:1
13Piles subjected to torsion显示文摘RANDOLPH M F 1981Journal of Geotechnical Engineering Division ASCE1981,107,8:1
14Design of driven piles in sand 显示文摘Randolph M F Dolwin J Beck R 1994Geotechnique1994,44,3:1
15An analysis of vertical deformation of pile groups显示文摘Randolph M F Wroth C P 1979Ge ó technique1979,29,4:1
16Science and empiricism in pile foundation design 显示文摘Randolph M F 2003G6otechnique2003,53,10:1
17Bearing capacity of caisson foundations on normally consolidated clay显示文摘HU Y X RANDOLPH M F 2002Soils and Foundations2002,42,5:1
18Analysis of piled embankments显示文摘HEWLETT J RANDOLPH M F 1988Ground Engineering1988,21,3:1
19Analysis of deformation of vertically loaded piles 显示文摘RANDOLPH M F WROTH C P 1978Geotech Eng Div ASCE1978,104,12:1
20Piles subjected to torsion显示文摘RANDOLPH M F 1981Journal of Geoteehnieal Engineering Division ASCE1981,107,8:1
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