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| 1 | 国际胃袖状切除专家共识:基于>12000手术病例的最佳操作指南显示文摘腹腔镜胃袖状切除术(1aparoscopic sleeve gastrectomy,LSG)系相对较新的减重手术方式。因其操作相对简单、治疗肥胖合并疾病及减重效果明显,逐步得以广泛接受。目前美国代谢与减重手术协会将其推荐为肥胖症治疗的单独标准术式。2011年3月25~26日, | 苏远涛 徐安安 朱江帆 Diaz AA Arvidsson D Baker RS Basso N Bellanger D Boza C El Mourad H France M Gagner M Galvao-Neto M Higa KD Himpens J Hutchinson CM Jacobs M Jorgensen JO Jossart G Lakdawala M Nguyen NT Nocca D Prager G Pomp A Ramos AC Rosenthal RJ Shah S Vix M Wittgrove A Zundel N | 2013 | 中国微创外科杂志2013，13，9： | 12 |
| 2 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 3 | Adult bone marrow stromal cells differentiate into neural cells in vitro显示文摘 | Sanchez Ramos J Song S Cardozo Pelaez F | | 0，，： | 2 |
| 4 | Analytical and mineralogical studies of ore and impurities from a chromite mineral using X - ray analysis, electrochemical and microscopy techniques 显示文摘 | Ramos S S Carbo A D Adelantado J V | 2008 | Talanta2008，74，5： | 1 |
| 5 | Electrochemical properties of sol-gel Li4/3 Ti5/3 O4 显示文摘 | Bach S Ramos J P Baffler N | 1999 | J Power Sources1999，8182，： | 1 |
| 6 | Sebaceous trichofolliculoma显示文摘 | Monteiro MB Mesquita-Guimàes J Ramos S | 1987 | Med Cutan Ibew Lat Am1987，15，3： | 1 |
| 7 | Adult bone marrow stromal cells differentiate into neural cells in vivo显示文摘 | Sanchez - Ramos J Song S Cardozo - Pelaez F | 2000 | Exp Neurol2000，164，： | 1 |
| 8 | Leakage detection and location in gas pipelines through an LPV identification approach显示文摘 | Lopes S P Azevedo T P Ramos J A | 2011 | C in Nonlinear Science and Numerical Simulation2011，12，16： | 1 |
| 9 | Comparative ecology of seed mass in Paychotria (Rubiaceae) Within and between species effects of seed mass on early performance显示文摘 | PAZ H MAZER S J MARTINEZ RAMOS M | 2005 | Functional Ecology2005，19，4： | 1 |
| 10 | An LPV modeling and identification approach to leakage detection in high pressure natural gas transportation networks显示文摘 | Lopes S P Ramos J A Carvalhs J L | 2011 | IEEE Transactions on Control Systems Technology2011，19，1： | 1 |
| 11 | Comparative structural analysis of et-glucosidase inhibitors on difference species: a computational study 显示文摘 | Narayana Moorthy N S Ramos M J Fernandes P A | 2012 | Arch Pharm (Weinheim)2012，345，4： | 1 |
| 12 | Adult bone marrow stromal cell differentiate into neural cells in vitro显示文摘 | Sanchez Ramos J Song S CARDOZO pelac F | 2000 | ExpNeuro 12000，164，： | 1 |
| 13 | Effect of water activity and temperature on growth and ochratoxin production by three strains of Aspergillus ochraeeus on an barley extract medium and onbarley grains 显示文摘 | Ramos A J Lavernia N Marin S | 1998 | Food Microbiol1998，44，12： | 1 |
| 14 | Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise : a randomized, double-blind, placebo-controlled, phase 3 trial 显示文摘 | Ferrannini E Ramos S J | 2010 | Diabetes Care2010，10，： | 1 |
| 15 | Adult bone marrow stromal cells differentiate into neural cells in vitro显示文摘 | Sanchez - Ramos J Song S Cardozo - Plaez F | 2000 | Exp Neurol2000，164，2： | 1 |
| 16 | Transverse myelitis affect- ing more than 4 spinal segments associated with systemic lupus erythematosus: clinical, immunological, and radiological characteristics of 22 patients 显示文摘 | Espinosa G Mendizabal A Minguez S Ramo - Tello C Capellades J Olive A Cervera R | 2010 | Semin Arthritis Rheum2010，39，4： | 1 |
| 17 | Phylogeography of the endangered rosewood Dalbergia nigra (Fabaceae): insights into the evolutionary history and conservation of the Brazilian Atlantic Forest显示文摘 | Ribeiro R A Lemos J P Ramos A C S | 2011 | Heredity2011，106，： | 1 |
| 18 | 显示文摘 | Ramos de Debiaggi S Campillo J M | 1999 | Journal of Materials Research1999，14，： | 1 |
| 19 | The oxidant/antioxidant network: Role of melatonin 显示文摘 | Tan DX Cabrera J D'Apra D Sainz RM Mayo JC Ramos S | 1999 | Biol Signals Recept1999，8，12： | 1 |
| 20 | Isolation, characterization, and differentiation to hepatocyte-like cells of nonparenchymal epithelial cells from adult human liver 显示文摘 | Duret C Gerbal-Chaloin S Ramos J | 2007 | Stem Cells2007，25，7： | 1 |
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