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| 1 | 一项评价银屑病严重程度的3种量表(银屑病面积和严重性指数、医师全面评估指标和点阵系统医师)的评定者之间和之内可靠性的研究显示文摘Background: There is a lack of consensus as to the best way of monitoring psoriasis severity in clinical trials. The Psoriasis Area and Severity Index (PASI) is the most frequently used system and the Physician’s Global Assessment (PGA) is also often used. However, both instruments have some drawbacks and neither has been fully evaluated in terms of ‘validity’and ‘reliability’as a psoriasis rating scale. The Lattice System Physician’s Global Assessment (LS-PGA) scale has recently been developed to address some disadvantages of the PASI and PGA. Objectives: To evaluate the inter-rater and intra rater reliability of the PASI, PGA and LS-PGA. Methods: On the day before the study, 14 dermatologists (raters), with varied experience of assessing psoriasis, received detailed training (2.5 h) on use of the scales. On the study day, each rater evaluated 16 adults with chronic plaque psoriasis in the morning and again in the afternoon. Raters were randomly assigned to assess subjects using the scales in a specific sequence, either PGA, LS-PGA, PASI or PGA, PASI, LS-PGA. Each rater used one sequence in the morning and the other in the afternoon. The primary endpoint was the inter-rater and intrarater reliability as determined by intraclass correlation coefficients (ICCs). Results: All three scales demonstrated ‘substantial’(a priori defined as ICC > 80%) intrarater reliability. The inter-rater reliability for each of the PASI and LS-PGA was also ‘substantial’and for the PGA was ‘moderate’(ICC 75%). Conclusions: Each one of the three scales provided reproducible psoriasis severity assessments. In terms of both intrarater and inter-rater reliability values, the three scales can be ranked from highest to lowest as follows: PASI, LS-PGA and PGA. | Berth-Jones J. Grotzinger K. Rainville C. 周少娜 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，，12： | 8 |
| 2 | Pain - related emotionsmodulate experimental pain perception and autonomic re-sponses 显示文摘 | Rainville P Bao QVH Chretien P | 2005 | Pain2005，118，3： | 1 |
| 3 | Psychological distress among adolescents living with a parent with advanced cancer显示文摘 | Rainville F Dumont S Simard S | 2012 | Psychosoc Oncol2012，30，5： | 1 |
| 4 | Hypno- sisModulates Activity in Brain Structures Involved in the Regulation of Consciousness显示文摘 | Rainville P Hofbauer RK BushnellMC | 2002 | J Cogn Neurosci2002，14，6： | 1 |
| 5 | UPLC/MSE ; a new approach for generating molecular fragment information for biomarker structure elucidation 显示文摘 | Robert SP Kelly AJ Rainville P | 2006 | Rapid Commun Mass Spectrom2006，20，13： | 1 |
| 6 | What can the history and physical examination tell us about low back pain显示文摘 | Rainvile J Kent DL | 1992 | JAMA1992，268，： | 1 |
| 7 | Pain-ielated emotions modulate experimental pain perception and autonomic responses显示文摘 | Rainville P Bau Q V Chretlon P | 2005 | Pain2005，118，8： | 1 |
| 8 | Pain affect encoded in human anterior cingulate but not somatosensory cortex 显示文摘 | RAINVILLE P DUNCAN GH PRICE DD | 1997 | Science1997，277，5328： | 1 |
| 9 | Vascular disease is associated with facet joint osteoarthritis显示文摘 | Suri P Katz JN Rainville J | 2010 | Osteoarthritis Cartilage2010，18，9： | 1 |
| 10 | Establishing A Link Between Heart Rate and Pain in Healthy Subjects: A Gender Effect 显示文摘 | LAFLAMME Y T RAINVILLE P MARCHAND S | 2005 | The Journal of Pain2005，6，6： | 1 |
| 11 | Proteomic evaluation of citrate-coated silver nanoparticles toxicity in Daphnia magna显示文摘 | Rainville LC Carolan D Varela AC | 2014 | Analyst2014，139，7： | 1 |
| 12 | A study examininginter and intrarater reliability of three scales for measuring severity of psoriasis: psoriasis area and severity index, physician' s global assessment and lattice system physician' s global assessment 显示文摘 | BERTH-JONES J GROTZINGER K RAINVILLE C et al | 2006 | Br J Derma-tol2006，155，4： | 1 |
| 13 | Pain affect encoded in human anterior cingulate but not somatosensory cortex显示文摘 | Rainville P Duncan GH Price DD | 1997 | Science1997，277，5328： | 1 |
| 14 | Executive function deficits in patients with dementia of the Alzheimer' s type 显示文摘 | Rainville C Ameiva H Lafont S | 2002 | Arch Clin Neuropsychol2002，17，6： | 1 |
| 15 | Predictors of patient - reported re- covery from motor or sensory deficits two years after acute symptom- atic lumbar disk herniation显示文摘 | Suri P Rainville J Gellhom A | 2012 | PM R2012，4，12： | 1 |
| 16 | Observations of Energetic High- Waven-umber Internal Waves in the Kuroshio显示文摘 | Rainville L Pinkel R | 2005 | Journal of PhysicalOceanography2005，34，7： | 1 |
| 17 | UPLC/MS: a new approach for generating molecular fragment information for biomarker structure elucidation 显示文摘 | Plumb R S Johnson K A Rainville P | 2006 | Rapid Commun Mass Sp2006，20，19： | 1 |
| 18 | Comparison of to tal lumbosacral flexion and true lumbar flexion measured by a dual inclinometer technique显示文摘 | Rainville J Sobel J B Hartigan C | 1994 | Spine1994，19，23： | 1 |
| 19 | What can the bistory and physical examination tell about low back pain 显示文摘 | Deyo RA Rainville J Kent DL | 1992 | JAMA1992，268，6： | 1 |
| 20 | Bayesian classification and unsupervised learning for isolating weeds in row crops显示文摘 | De Rainville F M Durand A Fortin F A | 2014 | Pattem Analysis and Applications2014，17，2： | 1 |
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