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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Preoperative magnetic resonance Imaging screening for a surgical decision regarding the approach for anterior spine fusion at the clervicothoracic junction显示文摘 | Fraser J F Diwan A D Peterson M | 2002 | SPINE2002，27，7： | 2 |
| 3 | Structure and function of selectable and non-selectable transgenes in maize after introduction by particle bombardment 显示文摘 | Register J C Peterson D J | 1994 | Plant Mol Biol1994，25，： | 1 |
| 4 | The environmental fate of phthalate esters: a literature review显示文摘 | Stales C A Peterson D R Parkerton T F Adams W J | 1997 | Chemosphere1997，35，4： | 1 |
| 5 | Provisional stenting strategies:systematic overview and implications for clinical decision making显示文摘 | Cantor E J Peterson E D Popma J J | 2001 | J Am Coll Cardiol2001，36，： | 1 |
| 6 | Understanding relationships among multiple ecosystem services显示文摘 | Bennett E M Peterson G D Gordon L J | 2009 | Ecol Let2009，，12： | 1 |
| 7 | Effects of soy isoflavone consumption on bone structure and milk mineral concentra-tion in a rat model of lactation-associated bone loss显示文摘 | Peterson C A Schnell J D Kubas K L | 2009 | EuropeanJournal of Nutrition2009，48，2： | 1 |
| 8 | Estimating the foliar bio-chemical concentration of leaves with reflectance spectrometry:testing the kokaly and dark methodologies显示文摘 | Curran P J Dungan J L Peterson D L | 2001 | Remote Sens En-viron2001，76，3： | 1 |
| 9 | The environmental fate of phthalate esters: a literature review 显示文摘 | Stales C A Peterson D R Parkerton T F Adams W J | 1997 | Chemosphere1997，35，4： | 1 |
| 10 | Earnings conference calls and stock returns: The incremental informativeness of textual tone显示文摘 | Price S M Doran J S Peterson D R | 2012 | Journal of Banking & Finance2012，36，4： | 1 |
| 11 | Variation in poly-phenol oxidase activity and quality characteristics among hard white wheat and hard red winter wheat samples 显示文摘 | Park W J Shelton D R Peterson C J | 1997 | Cereal Chemistry1997，74，： | 1 |
| 12 | An Imaging Interferometer for Terrestrial Remote Sensing显示文摘 | Hammer P D Valero F P J Peterson D L | 1993 | SPIE1993，1937，： | 1 |
| 13 | A Bayesian approach for multiple response surface optimization in the presence of noise variables显示文摘 | Castillo E D Peterson J J | 2004 | J Applied Statistics2004，31，3： | 1 |
| 14 | Analysis in variation in cis-9,tmns-11- conjugated linoleic acid(CLA) in milk fat of dairy cows显示文摘 | PETERSON D G KEISEY J A | 2002 | Journal of Dairy Science2002，85，9： | 1 |
| 15 | Variation in polyphenol oxidase activity and quality characteristics among hard white wheat and hard red winter wheat sample显示文摘 | Park W J Shelton D R Peterson C J | 1997 | Cereal Chem1997，74，1： | 1 |
| 16 | Construction of plant bacterial artificial chromosome ( BAC ) libraries : An illustrated guide 显示文摘 | Peterson D G Tomkins J P Frisch D A | 2000 | Journal of Agricultural Genomics2000，5，： | 1 |
| 17 | Cortical development in roots of the aquatic plant Pontederia cordata (Pontederiaceae) 显示文摘 | SEAGO J L PETERSON C A ENSTONE D E | 2000 | American Journal of Botany2000，87，： | 1 |
| 18 | Mycoplmgous grazing and food preference of Proisotoma minuta ( Collembola: Isotomidae) and Onychiurus encarpatus (Collembola: Onychiuridae) 显示文摘 | Lartey R T Curl E E Peterson C M Harper J D | 1989 | Environmental Entomology1989，，18： | 1 |
| 19 | Variation in Polyphenol Oxidase Activity and Quality Characteristics Among Hard Whire Wheat and Hard Red Winter Wheat Samples显示文摘 | Park W J Shelton D R Peterson C J | 1997 | Cereal Chem1997，74，1： | 1 |
| 20 | Ecological and evolutionary forces shaping microbial diversity in the human intestine显示文摘 | Peterson D A Gordon J I | 2006 | Cell2006，124，： | 1 |
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