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| 1 | Relationship between skin fold thickness and insulin resistance in the essential hypertensive patients in Vietnam显示文摘Previous studies reported a close relationship between obesity and insulin resistance in the essential hypertensive patients. Objective In this study, we examined the relationship between the skin fold thickness and insulin resistance then developed a formula to estimate the insulin resistance index according to the skin fold thickness in the essential hypertensive patients. Subjects and Methods Medical records of 80 patients (37 males, 43 females) were reviewed and the data were tabulated. Anthropometric indexes (including height, weight, waist circumference, hip circumference, and skins fold thickness at 5 fatty difference points on the Erdheim diagram), fasting plasma glucose and insulin concentration were recorded. The mean age was 57.0±9.2 years. The insulin resistance index was calculated following the Homeostasis Model Assessment (HOMA) formula. Results Compared with the group with BMI<23kg/m2, the group with BMI≥23 kg/m2 had higher fasting insulin concentration (8.85 ± 4.97 pmol/L vs 15.60 ± 8.70 pmol/L, P<0.001 ) and higher insulin resistance index in (2.15±1,24 vs 3.76±2.22, P<0.001). No significant difference in fasting plasma insulin concentration,insulin resistance index between male and female was observed (P>0.05). There was a positive correlation between skin fold thickness and the fasting insulin concentration and insulin resistance index. The skin fold thickness at point A8 had the best coefficient correlated with fasting plasma insulin(r=0.79, P<0.001) and insulin resistance index (r= 0.79, P < 0.001). A formula to estimate the insulin resistance index by skin fold thickness at point A8 as: Insulin resistance index = 0.12 × [skin fold thickness at A8 point (mm)] - 1.Conclusion: In the essential hypertensive patients, the formula to estimate insulin resistance index as 0.12 × [skin fold thickness at A8 point (mm)]-1 may predict accurately the level of insulin resistance. | Toan C Nguyen Khoa TA Pham Quyen TL Do Cuong T Nguyen Diep D Nguyen Vinh G Le Cong D Nguyen | 2005 | Journal of Geriatric Cardiology2005，2，4： | 4 |
| 2 | 法国POLA研究组评估2016WHO弥漫性胶质瘤分类的预后价值显示文摘新的WHO分类中弥漫性胶质瘤定义更为精确,包括1p/19q共缺失、IDH1/2突变和组蛋白H3-K27M突变。该文目的是法国POLA研究组对更新的WHO(2016)分类的预后价值进行评估。所有送至中心行病理检查和纳入法国全国性POLA队列研究中的高级别少突胶质细胞瘤, | Tabouret E Nguyen A T Dehais C, et al. 李晓玲 王行富 | 2016 | 临床与实验病理学杂志2016，32，12： | 3 |
| 3 | Skin fold thickness at abdomen:a simple anthropometric measurement may compliment metabolic syndrome definition in patients with normal waist circumference显示文摘Backgroud and Objectives Previous studies have reported that skin fold thickness (SF) strongly correlated with insulin resistance in the metabolic syndrome (MetS). In this study, we developed a MetS definition by SF at A8 point (SFA8) on Erdheim diagram(MetSSFA8) in essential hypertensive patients. Subjects and Methods Medical records of 268 essential hypertensive patients (126males and 122 females) were analyzed, including 210 non-diabetic patients (NDM group) and 58 patients with diabetes (DM group).The mean age was 61.4 ± 9.9 and 59.0 ± 11.0 years, respectively. The control group consisted of 90 non-diabetic, non-hypertensive patients with a mean age of 58.0 ± 11.3 years. The proposed MetSSFA8 definition included SFA8 specific values ( ≥30 mm in female and ≥27 mm in male) and at least two of the following: raised triglyceride levels ( ≥1.7 mmol/L), or specific treatment for this lipid abnormality; raised blood pressure (SBP≥130 mmHg and/or DBP≥85 mmHg), or treatment of previously diagnosed hypertension;reduced HDL-cholesterol (< 1.03 mmol/L in men, <1.29 mmol/L in women), or specific treatment for this lipid abnormality; raised fasting plasma glucose (≥5.6 mmol/l), or previously diagnosed DM. Metabolic Syndrome by the National Cholesterol Education Program and International Diabetes Federation definitions were determined with abdominal obesity defined by Asia-Pacific criteria for waist circumference (NCEPA and IDFA). Results The percentage of MetS as defined by NCEPA, IDFA and MetSSFA8 in NDM group was lower than that of NCEPA, IDFA and MetSSFA8 in DM group [OR=7.7 (95%CI, 2.9-20.2) and 2.5 (95%CI, 1.4-4.8) and 2.7(95%CI, 1.3-5.6), respectively] and higher than that of the control group [OR=53.3 (95%CI, 16.7-170.6), 5.8 (95%CI, 2.6-13.2) and18.8 (95%CI, 7.3-48.7), respectively]. The percentage of MetS by NCEPA, IDFA and MetSSFA8 in males in NDM group was lower than the percentage of MetS by NCEPA, IDFA and MetSSFA8 in females in NDM group (50.8% and 77.9%, P< 0.001; 15,9% and 67.2%, P< 0.001; 60.3% and 73.8%, P <0.05, respectively). In subjects with normal WC or both normal WC and BMI, the percentage of MetS by SFAS was higher than that the percentage of MetS by NCEPA (36.9% and 50.8%, P< 0.05 and 36.0% and 51.0%, P< 0.05).The sensitivity, specificity, false positive rate, positive predictive value, negative predictive value of MetSSFA8 assessed with NCEPA definitions were 0.87, 0.73, 0.27, 0.79 and 0.82, respectively. There was a close agreement between MetSSFA8 and NCEPA (The coefficient of Kapa was 0.60, P< 0.001). Conclusions The MetSSFA8 definition was developed which may be useful in order to define and manage MetS in patients with normal WC or normal weight. | Toan C Nguyen Thai Q Ngo Son V Nguyen Hieu T Luong Khoa TA Pham Cong D Nguyen | 2006 | Journal of Geriatric Cardiology2006，3，2： | 2 |
| 4 | Complete mitochondrial DNA sequence of the Australian freshwater crayfish,Cherax destructor (Crustacea:Decapoda:Parastacidae):a novel gene order revealed显示文摘 | Miller A D Nguyen T T Burridge C P | 2004 | Gene2004，，331： | 1 |
| 5 | A new technique for rapid tracking of frequency deviation based on level crossing显示文摘 | NGUYEN C T SRINIVASAN K A | 1984 | IEEE Trans on PAS1984，103，8： | 1 |
| 6 | Laterally driven poly-silicon resonant microstructures 显示文摘 | Tang W C Nguyen Tu-Cuong H Howe R T | 1989 | Sensors and Actuators1989，20，12： | 1 |
| 7 | Nutri?ent-gene interaction: metabolic genotype-phenotype re?lationship显示文摘 | GO V L NGUYEN C T HARRIS D M | 2005 | TheJournal of Nutrition2005，135，12： | 1 |
| 8 | Improved LVRT capacity and power smoothening of DFIG wind turbine systerns显示文摘 | NGUYEN T H LEE D C | 2011 | J Power Electron2011，11，4： | 1 |
| 9 | Single measurement of troponin T for early prediction of infarct size,congestive heart failure,and pulmonary hypertension in an animal model of myocardial infarction显示文摘 | Jiang B H Nguyen Q T Tardif J C | | 0，，3： | 1 |
| 10 | Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2显示文摘 | NGUYEN T PICKETT C B | 2000 | Proc Natl Acad Sci USA2000，97，12： | 1 |
| 11 | Androgens activate mitogen-activated protein kinase signaling: Role in neuroprotection 显示文摘 | Nguyen T V Yao M Pike C J | 2005 | J Neurochem2005，94，6： | 1 |
| 12 | Galectin-1, an endogenous leetin produced by thymic epithelial cells, induces apoptosis of human thymocytes显示文摘 | Perillo N L Uittenbogaart C H Nguyen J T | 1997 | J Exp Med1997，185，10： | 1 |
| 13 | Feasibility of a randomized controlled trial to evaluate Text Reminders for Immunization Compliance in Kids (TRICKs) 显示文摘 | Ahlers-Schmidt C R Chesser A K Nguyen T | 2012 | Vaccine2012，30，36： | 1 |
| 14 | Prognosis and prediction of response to surgery in allergi patients with chronic sinusitis显示文摘 | LAVIGNE F NGUYEN C T CAMERON L | 2002 | J Allergy Clin Immunol2002，105，： | 1 |
| 15 | Performance Evaluation of a Semi-Active Magnetorheological Mount 显示文摘 | Ciocanel C Nguyen T Schroeder C | 2008 | SAE Technical Paper Series2008，，： | 1 |
| 16 | Five year results of viscocanalostomy 显示文摘 | Shaarawy T Nguyen C Schnyder C | 2003 | Br J Ophthalmol2003，87，： | 1 |
| 17 | Mechanisms for the maintenance and eventual degradation of neurofilament proteins in the distal segments of severed goldfish mauthner axons 显示文摘 | Raabe TD Nguyen T Archer C | 1996 | J Neurosci Res1996，16，： | 1 |
| 18 | Graphene oxide, highly reduced graphene oxide, and graphene: Versatile building blocks for carbon-based materials显示文摘 | Owen C Compton SonBinh T Nguyen | 2010 | Small2010，6，6： | 1 |
| 19 | Development of an en- vironmentally friendly halogen-free phosphorus-nitrogen bond flame retardant for cotton fabrics显示文摘 | NGUYEN T D CHANG S C CONDON B | 2012 | Polymer Advanced Technology2012，23，： | 1 |
| 20 | Differential expression of caprine beta-defensins in digestive and respiratory tissues显示文摘 | Zhao C Nguyen T Liu L | | 0，，11： | 1 |
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