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| 1 | Human selenium supplementation as assessed bychanges in blood selenium concentration and glutathioneperoxidase activity显示文摘 | Nève J | 1995 | J Trace Elem Med Biol1995，，2： | 1 |
| 2 | Selenium supplementation in rheumatoid arthritis investigated in a double blind, placebo-controlled trial显示文摘 | Anne Peretz Vania Siderova Jean Nève | 2001 | Scandinavian Journal of Rheumatology2001，，4： | 1 |
| 3 | Vanadium-dependent activation of glucose transport in adipocytes by catecholamines is not mediated via adrenoceptor stimulation or monoamine oxidase activity显示文摘BACKGROUND Benzylamine and methylamine activate glucose uptake in adipocytes.For tyramine,this effect has even been extended to cardiomyocytes.AIM To investigate the effects of catecholamines and other amines on glucose uptake.METHODS A screening compared 25 biogenic amines on 2-deoxyglucose(2-DG)uptake activation in rat adipocytes.Pharmacological approaches and transgenic mouse models were then used to decipher the mode of action of several hits.RESULTS In rat adipocytes,insulin stimulation of 2-DG uptake was reproduced with catecholamines.100μmol/L or 1 mmol/L adrenaline,noradrenaline,dopamine and deoxyepinephrine,maximally activated hexose transport only when sodium orthovanadate was added at 100μmol/L.Such activation was similar to that already reported for benzylamine,methylamine and tyramine,well-recognized substrates of semicarbazide-sensitive amine oxidase(SSAO)and monoamine oxidase(MAO).Several,but not all,tested agonists ofβ-adrenoreceptors(β-ARs)also activated glucose transport whileα-AR agonists were inactive.Lack of blockade byα-andβ-AR antagonists indicated that catecholamine-induced 2-DG uptake was not mediated by AR stimulation.Adipocytes from mice lackingβ1-,β2-andβ3-ARs(triple KO)also responded to millimolar doses of adrenaline or noradrenaline by activating hexose transport in the presence of 100μmol/L vanadate.The MAO blocker pargyline,and SSAO inhibitors did not block the effects of adrenaline or noradrenaline plus vanadate,which were blunted by antioxidants.CONCLUSION Catecholamines exert unexpected insulin-like actions in adipocytes when combined with vanadium.For limiting insulin resistance by activating glucose consumption at least in fat stores,we propose that catecholamine derivatives combined with vanadium can generate novel complexes that may have low toxicity and promising anti-diabetic properties. | Jessica Fontaine Geneviève Tavernier Nathalie Morin Christian Carpéné | 2020 | World Journal of Diabetes2020，11，12： | 2 |
| 4 | Thiobarbituric acid reactive substances as a marker of oxidative stress in healthy subjects and in patients with impairment in trace element status显示文摘 | Wasowicz W Nève J van Gossum J | 1993 | Clinical Nutrition1993，2，： | 1 |
| 5 | Inventory, evolution and expression profiling diversity of the LEA (late embryogenesis abundant) protein gene family in Arabidopsis thaliana 显示文摘 | Bies-Ethève N Gaubier-Comella P Debures A | 2008 | Plant Mol Biol2008，67，12： | 1 |
| 6 | Nucleolus and c-Myc:potential targets of cardenolide-mediated antitumor activity显示文摘 | Mijatovic T De Nève N Gailly P | 2008 | Mol Cancer Ther2008，7，5： | 1 |
| 7 | Prolactin receptor signaling is essential for perinatal brown adipocyte function: a role for insulin-like growth factor-2显示文摘 | Viengchareun S Serve N Fève B | 2008 | PloS One2008，2，： | 1 |
| 8 | Short-term effects of obestatin on hexose uptake and triacylglycerol breakdown in human subcutaneous adipocytes显示文摘AIM To study complete dose-dependent effects of obestatin on lipolytic and glucose transport activities in human adipocyte preparations highly responsive to insulin.METHODS Adipocytes were prepared by liberase digestion from subcutaneous abdominal adipose tissue obtained from overweight subjects undergoing plastic surgery. The index of lipolytic activity was the glycerol released in the incubation medium, while glucose transport was assessed by [~3H]-2-deoxyglucose uptake assay.RESULTS When tested from 0.1 nmol/L to 1 μmol/L, obestatin did not stimulate glycerol release; it did not inhibit the lipolytic effect of isoprenaline and did not alter the insulin antilipolytic effect. Obestatin hardly activated glucose transport at 1 μmol/L only. Moreover, the obestatin stimulation effect was clearly lower than the threefold increase induced by insulin 100 nmol/L.CONCLUSION Low doses of obestatin cannot directly influence lipolysis and glucose uptake in human fat cells. | Christian Carpéné Francisco Les David Estève Jean Galitzky | 2018 | World Journal of Diabetes2018，9，1： | 0 |
| 9 | 查看详情显示文摘 | Mijatovic T De Nève N Bruyère C Simon G Dewelle J Van Quaquebeke E Van Der A.E Van Vynckt F Lefranc F Kiss R | | 0，，： | 1 |
| 10 | Dendritic cells exposed to nacystelyn are refractory to maturation and promote the emergence of alloreactive regulatory T cells显示文摘 | Olivier Vosters Jean Nève Dominique De Wit Fabienne Willems Michel Goldman Valerie Verhasselt | 2003 | Transplantation2003，，3： | 1 |
| 11 | Tracheal relaxation of five Ivorian anti-asthmatic plants: Role of epithelium and K + channels in the effect of the aqueous-alcoholic extract of Dichrostachys cinerea root bark显示文摘 | Geneviève Irié-N'guessan Pierre Champy Gisèle Kouakou-Siransy Armand Koffi Brou Jér?me Kablan Véronique Leblais | 2011 | Journal of Ethnopharmacology2011，，2： | 1 |
| 12 | Fourier Transform Infrared (FTIR) spectroscopy to monitor the cellularimpact of newly synthesized platinum derivatives显示文摘 | Gilles Berger Régis Gasper Delphine Lamoral-Theys Anja Wellner Michel Gelbcke Ronald Gust Jean Nève Robert Kiss Erik Goormaghtigh Fran?ois Dufrasne | 2010 | International Journal of Oncology2010，，3： | 1 |
| 13 | 查看详情显示文摘 | Mijatovic T Mahieu T JM Bmyère C De Nève N Dewelle J Simon G Dehoux M van der Aar E Haibe-Kains B Bontempi G Decaestecker C Van Quaquebeke E. Darro F | | 0，，： | 1 |
| 14 | 肿瘤坏死因子α抑制剂治疗皮肤结节病的疗效及耐受性观察:来自法国的一项46例病例研究显示文摘法国一项回顾性和前瞻性多中心研究对肿瘤坏死因子α抑制剂(anti-tumor necrosis factorα,TNFα抑制剂)治疗皮肤结节病的疗效和安全性做出了观察报告。自2004年1月~2016年1月期间,患者来自于多个教学医院、转诊中心、肺科、皮肤科和内科,病理确诊为结节病,并接受抗-TNFα治疗。对治疗反应的评估使用肺外器官严重度评分(ePOST,0为不受影响,6为非常严重)。 | Heidelberger V Ingen-Housz-Oro S Marquet A Mahevas M Bessis D Bouillet L Caux F Chapelon-Abric C Debarbieux S Delaporte E Duval-Modeste AB Fain O Joly P Marchand-Adam S Monfort JB Noёl N Passeron T Ruivard M Sarrot-Reynauld F Verrot D Bouvry D Fardet L Chosidow O Sève P Valeyre D 邓婕 张锡宝 | 2017 | 皮肤性病诊疗学杂志2017，24，4： | 0 |
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