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| 1 | Preservation solutions used during abdominal transplantation:Current status and outcomes显示文摘Organ preservation remains an important contributing factor to graft and patient outcomes. During donor organ procurement and transportation, cellular injury is mitigated through the use of preservation solutions in conjunction with hypothermia. Various preservation solutions and protocols exist with widespread variability among transplant centers. In this review of abdominal organ preservation solutions, evolution of transplantation and graft preservation are discussed followed by classification of preservation solutions according to the composition of electrolytes, impermeants, buffers, antioxidants, and energy precursors. Lastly, pertinent clinical studies in the setting of hepatic, renal, pancreas, and intestinal transplantation are reviewed for patient and graft survival as well as financial considerations. In liver transplants there may be some benefit with the use of histidine-tryptophan-ketoglutarate(HTK) over University of Wisconsin solution in terms of biliary complications and potential cost savings. Renal grafts may experience increased initial graft dysfunction with the use of Euro-Collins thereby dissuading its use in support of HTK which can lead to substantial cost savings. University of Wisconsin solution and Celsior are favored in pancreas transplants given the concern for pancreatitis and graft thrombosis associated with HTK. No difference was observed with preservation solutions with respect to graft and patient survival in liver, renal, and pancreas transplants. Studies involving intestinal transplants are sparse but University of Wisconsin solution infused intraluminally in combination with an intra-vascular washout is a reasonable option until further evidence can be generated. Available literature can be used to ameliorate extensive variation across centers while potentially minimizing graft dysfunction and improving associated costs. | Nicholas Latchana Joshua R Peck Bryan A Whitson Mitchell L Henry Elmahdi A Elkhammas Sylvester M Black | 2015 | World Journal of Transplantation2015，5，4： | 5 |
| 2 | Resection of pancreatic cystic neoplasms in recurrent acute pancreatitis prevents recurrent pancreatitis but does not identify more malignancies显示文摘BACKGROUND Recurrent acute pancreatitis(RAP)may be a presenting feature of and an indication for resection of pancreatic cysts,including intra-ductal papillary mucinous neoplasm(IPMN).Few data are available regarding the prevalence of malignancy and post-operative RAP in this population.AIM To study the role of resection to help prevent RAP and analyze if presentation as RAP would be a predictor for malignancy.METHODS This retrospective study assessed 172 patients who underwent surgical resection of pancreatic cystic neoplasms at a university hospital between 2002 and 2016.The prevalence of preoperative high-risk cyst features,and of neoplasia was compared between patients with and without RAP.To identify the cause of pancreatitis,all the patients had a detailed history of alcohol,smoking,medications obtained,and had cross-sectional imaging(contrast-enhanced computed tomography/magnetic resonance imaging)and endoscopic ultrasound to look for gallstone etiology and other structural causes for pancreatitis.The incidence of RAP post-resection was the primary outcome.RESULTS IPMN accounted for 101 cases(58.7%){[branch duct(BD)59(34.3%),main duct(MD)42](24.4%)}.Twenty-nine(16.9%)presented with RAP(mean 2.2 episodes):15 had BD-IPMN,8 MD-IPMN,5 mucinous cystic neoplasm and 1 serous cystic neoplasm.Malignancy was similar among those with vs without RAP for all patients[6/29(20.7%)vs 24/143(16.8%)]and IPMN patients[6/23(26.1%)vs 23/78(29.5%)],although tended to be higher with RAP in BD-IPMN,[5/15(33.3%)vs 3/44(6.8%),P=0.04].At mean follow-up of 7.2 years,1(3.4%)RAP patient had post-resection RAP.The mean episodes of acute pancreatitis before vs after surgery were 3.4 vs 0.02(P<0.0001).CONCLUSION Malignancy was not increased in patients with pancreatic cystic neoplasms who have RAP compared to those without RAP.In addition,specific cyst characteristics were not clearly associated with RAP.The incidence of RAP was markedly decreased in almost all patients following cyst resection. | Thiruvengadam Muniraj Harry R Aslanian Loren Laine Priya A Jamidar James F Farrell Kisha A Mitchell Ronald R Salem | 2021 | World Journal of Gastroenterology2021，27，15： | 3 |
| 3 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 4 | Programmed assembly of DNA functionalized quantum dots 显示文摘 | MITCHELL G P MIRKIN C A LETSINGER R L | 1999 | J Am Chem Soc1999，121，35： | 1 |
| 5 | Purification,bioactivity,and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF)显示文摘 | Bernhagen J Mitchell R A Calandra T | 1994 | Biochemistry1994，33，14： | 1 |
| 6 | Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53 : regulatory role in the innate immune response显示文摘 | Mitchell R A Liao H Chesney J | 2002 | Proc Natl Acad Sci U S A2002，99，1： | 1 |
| 7 | Edge location to subpixel values in digital imagery显示文摘 | TABATABAI A J MITCHELL O R | 1984 | IEEE Transactions on Pattern Analysis and Machine Intelligence1984，，2： | 1 |
| 8 | A fluo- rescent sensor for Cu2 + at the sub - ppm level显示文摘 | MITCHELL K A BROWN R G YUAN D | 1998 | Jour- nal of Photochemistry and Photobiology A: Chemistry1998，115，2： | 1 |
| 9 | Assessing variation in the radial profile of sap flux density in Pinus species and its effect on daily water use显示文摘 | Ford C Mcguire M A Mitchell R J | 2004 | Tree Physiology2004，24，3： | 1 |
| 10 | Direct observation of behaviour of Au nanoclusters on TiO2(110) at elevated temperatures显示文摘 | MITCHELL C E J HOWARD A CARGEN M EGDLL R G | 2001 | Surface Science2001，490，： | 1 |
| 11 | Macrophage migration inhibitory factor(MIF) sustains macrophage proinflammatory function by inhibiting p53: regulatory role in the innate immune response显示文摘 | Mitchell R A Liao H Chesney J | 2002 | Proc Nail Acad Sci USA2002，99，2： | 1 |
| 12 | Induction of heterosubtypic immunity to influenza A virus using a DNA vaccine expressing hemagglutinin-C3d fusion proteins显示文摘 | Mitchell J A Green T D Bright R A | 2003 | Vaccine2003，21，910： | 1 |
| 13 | Electrodepo- sition of copper and copper-aluminum alloys from a room- temperature ehloroaluminate molten salt 显示文摘 | Tierney B J Pitner W R Mitchell J A | 1998 | Journal of Electrochemical Society1998，145，9： | 1 |
| 14 | Rates of particulate pollution deposition onto leaf surfaces: Temporal and inter- species magnetic analyses 显示文摘 | Mitchell R Maher B A Kinnersley R | 2010 | Environmental Pollution2010，158，5： | 1 |
| 15 | New development in solid state fermentation: l-bioprocess and products 显示文摘 | PANDEY A C R SOCCOL C R MITCHELL D | 2000 | Process Biochemistry2000，35，10： | 1 |
| 16 | Massive hepatic necrosis and nodular regeneration in largemouth bass fed diets high in available carbohydrate 显示文摘 | GOODWIN A E LOCHMANN R T MITCHELL A J | 2002 | Journal of the World Aquaculture Society2002，33，4： | 1 |
| 17 | Soil Creep as a Rate Process显示文摘 | Mitchell J K Campanella R G Singh A | 1968 | Journal of the Soil Mechanics and Engineering Foundations1968，，： | 1 |
| 18 | Hyperleptinemia and reduced TNF-alpha secretion cause resistance of db/db mice to endotoxin显示文摘 | Madiehe A M Mitchell T D Harris R B | 2003 | Am J Physiol Regul Integr Comp Physiol2003，284，： | 1 |
| 19 | Problems with the Interpretation of Pharmacoecono- mic Analyses: A Review of Submissions to the Australian Pharmaceu- tical Benefits Scheme 显示文摘 | Hill S R Mitchell A S Henry D A | 2000 | Medical Association2000，283，16： | 1 |
| 20 | Modelling the urban water cycle 显示文摘 | Mein R G McMahon T A 2001 | 2001 | Environmental Modelling & Software2001，16，： | 1 |
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