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| 1 | Metabolic complications of hepatitis C virus infection显示文摘Hepatitis C virus(HCV) infection is a systemic disease that is implicated in multiple extrahepatic organ dysfunction contributing to its protean manifestations. HCV is associated with diverse extrahepatic disorders including atherosclerosis, glucose and lipid metabolic disturbances, alterations in the iron metabolic pathways, and lymphoproliferative diseases over and above the traditional liver manifestations of cirrhosis and hepatocellular carcinoma. The orchestration between HCV major proteins and the liver-muscle-adipose axis, poses a major burden on the global health of human body organs, if not adequately addressed. The close and inseparable associations between chronic HCV infection, metabolic disease, and cardiovascular disorders are specifically important considering the increasing prevalence of obesity and metabolic syndrome, and their economic burden to patients, the healthcare systems, and society. Cellular and molecular mechanisms governing the interplay of these organs and tissues in health and disease are therefore of significant interest. The coexistence of metabolic disorders and chronic hepatitis C infection also enhances the progression to liver fibrosis and hepatocellular carcinoma. The presence of metabolic disorders is believed to influence the chronicity and virulence of HCV leading to liver disease progression. This comprehensive review highlights current knowledge on the metabolic manifestations of hepatitis C and the potential pathways in which these metabolic changes can influence the natural history of the disease. | Rahul Chaudhari Sherouk Fouda Ashik Sainu Joseph M Pappachan | 2021 | World Journal of Gastroenterology2021，27，13： | 3 |
| 2 | Mitochondria and the aging heart显示文摘平均人的寿命显著地在大部分在成功地减少了重要健康风险的医药、治疗学的科学归因于进展的现代社会增加了。然而,先进年龄导致众多的改变到细胞并且能影响一个个人的全面健康和功能的 subcellular 部件。不令人惊讶地,先进年龄是为老人口在观察增加的病态和死亡的心疾病的发展的一个主要风险因素。看起来有正常的心的甚至健康的个人在放松条件下面工作,实际上有增加的危险性和危险强调。这被应力和疾病能随着时间的过去有到心和容器的影响惊讶。尽管,有在心上调查老化的效果的文学的很快成长的身体并且年龄相关的改变怎么影响心脏的功能,老化的生物学和内在的机制仍然保持不清楚。在这评论,我们在心上总结老化的效果并且在 mitochondrial 机能障碍上与特殊强调讨论细胞的老化的潜在的理论。 | Ketul R Chaudhary Haitham El-Sikhry John M Seubert | 2011 | Journal of Geriatric Cardiology2011，8，3： | 2 |
| 3 | Frequency and predictive factors of malignancy in residual thyroid tissue and cervical lymph nodes after partial thyroidectomy for differentiated thyroid cancer显示文摘 | Alzahrani AS AI Mandil M Chaudhary MA | 2002 | Surg2002，131，4： | 1 |
| 4 | McCune-Albright syndrome显示文摘 | Chaudhary AL | 2006 | Med J Aust2006，185，： | 1 |
| 5 | Using mixed anhydrides from amino acids and isobutyl chloroformate in N-aeylations: a case study on the elucidation of mechanism of urethane formation and starting amino acid liberation using carbon dioxide as the probe 显示文摘 | Chaudhary A Girgis M Prashad M | 2003 | Tetra Lett2003，44，29： | 1 |
| 6 | Inhibition of soluble epoxide hydrolase by trans-4- -benzoic acid is protective against ischemia-repeffusion injury显示文摘 | Chaudhary KR Abukhashim M Hwang SH | 2010 | J Cardiovasc Pharmacol2010，55，1： | 1 |
| 7 | Inheritance of shell-quality related egg traits at two stages in the early part of laying in chickens显示文摘 | Bah G S Chaudhary M L Sandhu J S | 1998 | Indian J Poult Sci1998，33，3： | 1 |
| 8 | Acetylcholine induced proliferation of fibroblastsand my ofibroblasts in vitrois Inhibited by tiotropium bromide显示文摘 | Pieper M P Chaudhary N J Park J E | 2007 | Life Sci2007，80，24： | 1 |
| 9 | Achievingcommunication efficiency through push-pull partitioning of semanticspaces to disseminate dynamic information 显示文摘 | BAGCHI A CHAUDHARY A GOODRICH M T | 2006 | IEEE Transactionson Knowledge and Data Engineering2006，18，10： | 1 |
| 10 | Performance evaluation of base-isolated Yama-age Bridge with high damping rubber bearings using recorded seismic data显示文摘 | Chaudhary M.T.A Abe M Fujino Y | | 0，，08： | 1 |
| 11 | FEM Modelling of a Large Piled Raft for Settlement Control in Weak Rock显示文摘 | Chaudhary M A | | 0，，11： | 1 |
| 12 | OPG/FDCR-1,a TNF receptor family member,is expressed in lymphoid cells and is up-regulated by ligating CD40显示文摘 | Yun T J Chaudhary P M Shu G L | 1998 | J Immunol1998，161，11： | 1 |
| 13 | Frequency and predictive factors of malignancy in residual thyroid tissue and cervical lymph nodes after partial thyroidectomy for thyroid cancer显示文摘 | Alzahrani AS AI Mahdi M Chaudhary MA | 2002 | Surgery2002，131，4： | 1 |
| 14 | A highly selective ammonia gas sensor using surface-ruthenated zinc oxide显示文摘 | ASLAM M CHAUDHARY V A MULLA I S | 1999 | Sensors and Actuators A1999，75，2： | 1 |
| 15 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study 显示文摘 | Kumarasamy KK Toleman MA Walsh TR Bagaria J Butt F Balakrishnan R Chaudhary U Doumith M Giske CG Irfan S Krishnan P Kumar AV Maharjan S Mushtaq S Noorie T Paterson DL Pearson A Perry C Pike R Rao B Ray U Sarma JB Sharma M Sheridan E Thirunarayan MA Turton J Upadhyay S Warner M Welfare W Livermore DM Woodford N | 2010 | Lancet Infect Dis2010，10，9： | 1 |
| 16 | Oxidative and antioxidative mechanisms in oral cancer and precancer: a review显示文摘 | Choudhari S K Chaudhary M Gadbail A R | 2014 | Oral Oncol2014，50，1： | 1 |
| 17 | Absorption heat pump with the TFE-TEGDME andTFE-H2O-TEGDME systems显示文摘 | CORONAS A VALLéS M CHAUDHARI S K | 1996 | Applied thermalengineering1996，16，4： | 1 |
| 18 | Detection of endogenous malondialdehyde-deoxyguanosine adducts in human live 显示文摘 | Chaudhary A K Nokubo M Reddy G R | 1994 | Science1994，265，5178： | 1 |
| 19 | Starvation, leptin and epithelial cell proliferation in the gastrointestinal tract of the mouse显示文摘 | Chaudhary M Mandir N FitzGerald A J | 2000 | Digestion2000，61，： | 1 |
| 20 | Correlation of radiological and clinical features of metanephric neoplasms in adults显示文摘 | Chaudhary H Raghvendran M Dubey D | 2004 | Indian J Cancer2004，41，1： | 1 |
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