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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 2 | Human mesenchymal stem cells overexpressing pigment epitheliumderived factor inhibit hepatocellular carcinoma in nude mice(摘要)显示文摘 | Gao, Y Yao, A Zhang, W Lu, S Yu, Y Deng, L Yin, A Xia, Y Sun, B Wang, X | 2010 | 南京医科大学学报(自然科学版)2010,30,8: | 25 |
| 3 | 肝细胞来源外泌体可能成为慢加急性肝衰竭患者肝再生和预后评估的生物标志物显示文摘【据Hepatology International 2021年8月报道】题:肝细胞来源外泌体可能成为慢加急性肝衰竭患者肝再生和预后评估的生物标志物(作者Jiao Y等)慢加急性肝衰竭(ACLF)患者虽然肝损伤严重,但是部分患者仍可以通过肝脏再生得以存活,因此ACLF患者的肝再生评估尤为重要。外泌体兼具肝脏活组织检查的特异性和外周血检测的非侵袭性的优点,可能是肝脏疾病潜在的生物标志物。本研究旨在建立ACLF肝再生的外泌体表达谱模型,探讨其在肝衰竭患者肝再生及预后评估中的作用。 | JIAO Y LU W XU P 焦彦 卢旺 陈煜 时红波 马迎民 | 2021 | 临床肝胆病杂志2021,37,10: | 8 |
| 4 | 相关性和一致性:这对相仿概念和测量方法的回顾与阐明(英文)显示文摘一致性(agreement)和相关性(correlation)是两个广泛使用的概念,用来评估变量之间的关联。虽然二者相似且相关,但是它们代表关联完全不同的概念。评估变量之间的一致性假设变量测量的是相同的结构,而在变量测量完全不同的结构时也可以评估它们之间的相关性。这种概念上的差异就要求使用不同的统计方法,并且当评估一致性或相关性时,统计方法根据数据的分布和研究者的兴趣可能会有所不同。例如,Pearson相关性,作为评估连续变量之间相关性的一种普遍测量方法,只有用于符合线性关系的变量时才能提供有用的信息;当用于不符合线性关系的变量时就无法提供准确信息甚至会产生误导。同样地,内部相关性,作为一种评估连续变量之间一致性的常用方法,如果一致性不好的实质正好是研究兴趣所在,那么该测量就不能为研究者提供充分的信息。本报告回顾了一致性和相关性的概念,并讨论了几种常用方法在应用中的差异。 | Liu JY Tang W Chen GQ Lu Y Feng CY Tu XM | 2016 | 上海精神医学2016,28,2: | 6 |
| 5 | Small interfering RNA inhibits SARS-CoV nucleocapsid gene expression in cultured cells and mouse muscles显示文摘 | Zhao P Qin ZL Ke JS Lu Y Liu M Pan W Zhao LJ Cao J Qi ZT | 2005 | 第二军医大学学报2005,26,10: | 4 |
| 6 | QUANTUM MECHANICAL MODEL AND SIMULATION OF GaAs/AlGaAs QUANTUM WELL INFRARED PHOTODETECTOR-Ⅱ ELECTRICAL ASPECTS显示文摘A complete quantum mechanical model for GaAs/AlGaAs quantum well infrared photodetectors(QWIPs) was presented. The photocurrent was investigated by the optical transition(absorption coefficient)between the ground state and the excited states due to the nonzero component of the radiation field along the sample growth direction. By studying the inter diffusion of the Al atoms across the GaAs/AlGaAs heterointer faces, the mobility of the drift diffusion carriers in the excited states was calculated. As a result, the measurement results of the dark current and the photocurrent spectra are explained theoretically. | Fu Y Willander M LU W | 2002 | 红外与毫米波学报2002,21,6: | 4 |
| 7 | Improved cryopreservation of human embryonic stem cells with trehalose显示文摘 | Wu CF Tsung HC Zhang W J Wang Y Lu JH Tang ZY Kuang YP Jin W Cui L Liu W Cao YL | 2006 | 中国生物学文摘2006,20,7: | 2 |
| 8 | Modeling of air back pressure in diecasting 显示文摘 | LEE W B LU H Y | 1999 | J of Materials Processing Technology1999,91,1: | 2 |
| 9 | Interoperability of Design Intent in Integrated Product and Process Design显示文摘Concurrent engineering is currently an overwhelming t rend in product development since it takes the down-stream product development issues and product life-cycle issues into consideration in up-front design pro cess. At this stage, evaluation, verification and validation of design concepts and design schemes is critical to the right-to-market product development. I dentification and extraction of design intent from the part digital mock-ups in different data formats and created in different CAD systems for DFX considerati on, evaluation, verification, and validation is crucial too. Traditionally, fro m manufacturing point of view, feature identification and extraction is to get t he features and feature-related information for manufacturing planning and inte gration. Presently, from the viewpoint of product development and product servi ce life cycle, design intent identification and extraction is to get all the des ign-related information for DFX consideration in early design stage, such as de sign for assembly, design for service, design for tooling, design for functional ity and design for environment etc. Therefore, how to successfully extract desi gn intent such as design and machining features and design-related information from the prototyping digital mock-ups created by different CAD systems for DFX consideration in upstream design stage is a very useful topic in integrated prod uct and process design and development. Presently, there are heterogeneous CAD systems in the market and the interoperat ion among the different CAD systems is indispensable. The interoperability of d ifferent CAD systems is by way of data exchanged technology such as STEP and IGE S. The critical weakness of this interoperation technology is that much of the design intent is lost in the interoperation process. Once the product digital m ock-ups is exchanged via data exchange technology such as IGES or STEP, the des ign intent including the dimension-driven design features and other attributes embedded in the part model are lost in the data translation process. Models rea d out of CAD systems come into other systems as featureless chunks of geometry e ntities. Obviously, the interoperation technology does not satisfy the industry need. It has been reported that this poor interoperation technology, which pro vides poor CAD models in neutral-format geometry had cost the automobile indust ry alone $1 billon per year. Fortunately, some researchers have been aware of t he criticality of this since only the United States industry spends billons of d ollars as a result of poor interoperability between computer-aided engineering software tools. In the past, product development was often done within a single company by co-located design team. In more recent years, there has been a busi ness paradigm shift in product development as the product development is being d one more often by geographically and temporally distributed design teams. There is a high level of outsourcing, not only of manufacturing but also of actual pr oduct development effort. Besides, product development across companies, and ev en within a single company, is often done within a heterogeneous software tool e nvironment. How to improve the interoperability of design intent created in het erogeneous software tool environment geographically has become a critical issue in next-generation product development system. Design intent in this research is defined as the outcome of design process. Des ign process goes from the identification of needs to satisfaction of that needs. Design intent satisfies this kind of needs. In this research, design intent i s created in a CAD system and embedded in part CAD model. The detailed design i ntent here includes design and manufacturing features and the feature-relat ed information such as feature parameters, feature relationships and some relate d characteristics such as associativity. Interoperability refers to the ability to share and communicate in the heterogeneous environment or heterogeneous soft | M W Fu W F Lu A Y C Nee S K Ong | 2002 | 厦门大学学报(自然科学版)2002,41,S1: | 2 |
| 10 | Study on the chemical constituents in Abrus mollis 显示文摘 | Lu W J Tian X Y Chen J Y | 2003 | West China J Pharm Sci2003,18,6: | 2 |
| 11 | QUANTUM MECHANICAL MODEL AND SIMULATION OF GaAs/AlGaAs QUANTUM WELL INFRARED PHOTO-DETECTOR-ⅠOPTICAL ASPECTS显示文摘A complete quantum mechanical model for GaAs?AlGaAs quantum well infrared photodetectors(QWIPs) is presented here. The model consisted of four parts: (1) Starting with the description of the electromagnetic field of the infrared radiation in the QWIP, effective component of the vector potential <| A z |> along the QWIP growth direction ( z axis) due to the optical diffraction grating was calculated. (2) From the wave transmissions and the occupations of the electronic states, it was discussed that the dark current in the QWIP is determined by the drift diffusion current of carriers thermally excited from the ground sublevel in the quantum well to extended states above the barrier. (3) The photocurrent was investigated by the optical transition (absorption coefficient between the ground state to excited states due to the nonzero <| A z |> ). (4) By studying the inter diffusion of the Al atoms across the GaAs?AlGaAs heterointerfaces,the mobility of the drift diffusion carriers in the excited states was calculated, so the measurement results of the dark current and photocurrent spectra can be explained theoretically. With the complete quantum mechanical descriptions of (1 4), QWIP device design and optimization are possible. | Fu Y Willander M Li Ning Lu W | 2002 | 红外与毫米波学报2002,21,5: | 2 |
| 12 | Hierarchical attributed graph representation and recognition of handwritten Chinese characters显示文摘 | LU S W YING R SUEN C Y | 1991 | Pattern Recognition1991,24,18: | 1 |
| 13 | UV curing behavior of methacrylated hyperbranched poly (amine-ester) s 显示文摘 | Wei H Y Lu Y Shi W F | 2001 | Journal of Applied Polymer Science2001,80,1: | 1 |
| 14 | 显示文摘 | Jia W Y Yuan H B Lu L Z | 1998 | Journal of Luminescence1998,7677,: | 1 |
| 15 | Traditional medicine in the treatment of drug addiction显示文摘 | Lu L Liu Y Zhu W | 2009 | Am J Drug Alcohol Abuse2009,35,1: | 1 |
| 16 | Changes in limestone sorbent morphology during CaO-CaCO3 looping at pilot scale显示文摘 | Hughes R W Macchi A Lu D Y | 2009 | Chemical Engineering & Technology2009,32,3: | 1 |
| 17 | HoxAlO activates transcription of the gene encoding mitogen- activated protein kinase phosphatase 2 (Mkp2)in myeloid cells显示文摘 | WANG H LU Y HUANG W | 2007 | J Biol Chem2007,282,16: | 1 |
| 18 | Proanthocyanidins from Lotus pedunculatus 显示文摘 | Foo L Y Lu Y Mcnabb W C | 1997 | Phytochemistry1997,45,8: | 1 |
| 19 | Expression of cyclooxygenase-2 (Cox-2) in human esophageal cancer and in vitro inhibition by a specific Cox-2 inhibitor, NS-398 显示文摘 | Yu H P Shi L Y Lu W H | 2004 | J Gastroenterol Hepatol2004,19,6: | 1 |
| 20 | Resonance light scattering and derived techniques in analytical chemistry: past, present, and future显示文摘 | Lu W Fernandez Band B S Yu Y | 2007 | Microchim Acta2007,158,: | 1 |