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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Metal exposure and Alzheimer's pathogenesis.显示文摘 | Liu G Huang W Moir RD Vanderburg CR Lai B Peng Z Tanzi RE Rogers JT Huang X | 2006 | 中国生物学文摘2006，20，9： | 8 |
| 3 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 4 | Hepatology International|富马酸丙酚替诺福韦片和富马酸替诺福韦二吡呋酯能够安全有效地阻断高病毒载量孕妇HBV的母婴垂直传播显示文摘HBV感染是一个严重的全球性健康问题,超过42%~52%的患者在围产期感染HBV。富马酸丙酚替诺福韦片(TAF)和富马酸替诺福韦二吡呋酯(TDF)是广泛用于治疗乙型肝炎的药物。沈阳市第六人民医院的Li等评估了TAF在阻断HBV母婴垂直传播方面的有效性和安全性。72例符合纳入标准的孕妇随机分为TDF组(300 mg/d,n=36)和TAF组(25 mg/d,n=36)。通过分析和比较两组孕妇及婴儿的临床和实验室数据,评估TAF和TDF的疗效及安全性。 | 王岩 刘星 李伯君 LI B LIU Z LIU X | 2022 | 临床肝胆病杂志2022，38，2： | 3 |
| 5 | 全颗粒饲料对奶牛生产性能的影响显示文摘饲料中的中性洗涤纤维(NDF)含量和饲料颗粒直径是影响瘤胃功能的重要因素。试验评估了以颗粒饲料为主的奶牛瘤胃健康情况、NDF消化率和生产性能。选取8头荷斯坦母牛(336±30 d,体重346±35 kg),随机分配到交叉重复试验组中,奶牛安置于牛栏,自由采食。试验期为3周,前两周是适应期,最后一周为数据收集期。各组饲粮原料相同,但物理形式不同,分为全混合日粮(TMR)和颗粒料(直径=8 mm)。两组间物理有效NDF(pe NDF)不同,TMR组为39.8%,颗粒料组为11.8%。在试验过程中,干物质采食量(DMI)、饮水量、瘤胃反刍时间、瘤胃温度和pH情况均记录。3周后收集粪样,确定潜在的可消化NDF总消化率(pdNDF)。每阶段结束后计算平均日增重和饲料转化率。颗粒料组的DMI、DMI/体重和饮水量更高。而两组间平均日增重和饲料转化率无显著差异。颗粒料组的瘤胃反刍时间为241 min·d-1低于TMR组的507 min·d-1。饲料的不同物理外形对瘤胃温度、瘤胃pH无显著影响。TMR组的pdNDF总消化率为90.25%高于颗粒料组的86.82%。试验结果表明,动物易接受完整的颗粒饲料,DMI较高,且反刍时间减少,但瘤胃pH无显著变化。TMR组的pdNDF消化率显著增加。尽管两组奶牛在DMI和纤维消化方面表现不同,但总体表现相似,两组饲料的保存时间与其物理形式有关。在短期内,提供能满足NDF需求的完全颗粒饲料可改善瘤胃健康状况和动物生产性能,而较长时间的数据则需要进一步试验。 | Wang J Yang M Cao M Lin Y Che L Q Duraipandiyan V Al-Dhabi N A Fang Z F Xu S Y Feng B Liu G Wu D Bonfante E Palmonari A Mammi L Canestrari G Fustini M Formigoni A | 2016 | 饲料博览2016，0，12： | 2 |
| 6 | Microstructural Probing of (1-x)GeS2-xGa2S3 System Glasses By Raman Scattering显示文摘 | H Z Tao X J Zhao C B Jing S Liu | | Journal of Wuhan University of Technology (Materials Science Edition)0，，： | 2 |
| 7 | Terahertz Semiconductor Quantum Well Devices显示文摘For eventually providing terahertz science with compact and convenient devices,terahertz (1~10THz) quantum-well photodetectors and quantum-cascade lasers are investigated.The design and projected detector performance are presented together with experimental results for several test devices,all working at photon energies below and around optical phonons.Background limited infrared performance (BLIP) operations are observed for all samples (three in total),designed for different wavelengths.BLIP temperatures of 17,13,and 12K are achieved for peak detection frequencies of 9.7THz(31μm),5.4THz(56μm),and 3.2THz(93μm),respectively.A set of THz quantum-cascade lasers with identical device parameters except for doping concentration is studied.The δ-doping density for each period varies from 3.2×1010 to 4.8×1010cm-2.We observe that the lasing threshold current density increases monotonically with doping concentration.Moreover,the measurements for devices with different cavity lengths provide evidence that the free carrier absorption causes the waveguide loss also to increase monotonically.Interestingly the observed maximum lasing temperature is best at a doping density of 3.6×1010cm-2. | Liu H C Luo H Ban D Waichter M Song C Y Wasilewski Z R Buchanan M Aers G C SpringThorpe A J Cao J C Feng S L Williams B S Hu Q | 2006 | Journal of Semiconductors2006，27，4： | 2 |
| 8 | Measurements of critical parameters and saturated densities of dimethyl ether 显示文摘 | Wu J T Liu Z G Wang B | 2004 | Journal of Chemical and Engineering Data2004，49，3： | 2 |
| 9 | Magnetic texture in Fe nanowire array显示文摘 | Wang J B Zhou X Z Liu Q F | 2004 | Nanotecnology2004，15，： | 2 |
| 10 | Laser patterning for the study of MSC cardiogenic differentiation at the single-cell level显示文摘Mesenchymal stem cells(MSCs)have been cited as contributors to heart repair through cardiogenic differentiation and multiple cellular interactions,including the paracrine effect,cell fusion,and mechanical and electrical couplings.Due to heart–muscle complexity,progress in the development of knowledge concerning the role of MSCs in cardiac repair is heavily based on MSC–cardiomyocyte coculture.In conventional coculture systems,however,the in vivo cardiac muscle structure,in which rod-shaped cells are connected end-to-end,is not sustained;instead,irregularly shaped cells spread randomly,resulting in randomly distributed cell junctions.Consequently,contact-mediated cell–cell interactions(e.g.,the electrical triggering signal and the mechanical contraction wave that propagate through MSC–cardiomyocyte junctions)occur randomly.Thus,the data generated on the beneficial effects of MSCs may be irrelevant to in vivo biological processes.In this study,we explored whether cardiomyocyte alignment,the most important phenotype,is relevant to stem cell cardiogenic differentiation.Here,we report(i)the construction of a laser-patterned,biochip-based,stem cell–cardiomyocyte coculture model with controlled cell alignment;and(ii)single-cell-level data on stem cell cardiogenic differentiation under in vivo-like cardiomyocyte alignment conditions. | Zhen Ma Qiuying Liu Huaxiao Yang Raymond B Runyan Carol A Eisenberg Meifeng Xu Thomas K Borg Roger Markwald Yifei Wang Bruce Z Gao | 2013 | Light(Science & Applications)2013，2，1： | 2 |
| 11 | Chimeric calcium/calmodulin-dependent protein kinase in tobacco: differential regulation by calmodulin isoforms显示文摘 | LIU Z XIA M POOVAIAH B W | 1998 | Plant Molecular Biology1998，38，： | 1 |
| 12 | Cloning and expression of a mannanase gene from Erwinia carotovora CXJZ95-198 显示文摘 | ZHANG Y X LIU Z C CHEN X B | 2007 | Annals of Microbiology2007，57，4： | 1 |
| 13 | Electrodeposition of Pt-Ru nanoparticles on carbon nanotubes and their electrocatalytic properties for methanol electrooxidation 显示文摘 | He Z B Chen J H Liu D Y | 2004 | Diamond and Related Materials2004，13，10： | 1 |
| 14 | Myoblast Therapy: from Bench to Bedside 显示文摘 | LIU Z WU Y CHEN B G | 2006 | Cell Transplant2006，15，6： | 1 |
| 15 | Experimental study of the inert effect of R134a and R227ea on explosion limits of the flammable refrigerants显示文摘 | Yang Z Liu B Zhao H B | 2004 | Experimental Thermal and Fluid Science2004，28，： | 1 |
| 16 | Explosive Consolidation of Amorphous Cobalt-Based Alloys 显示文摘 | Liu Z Y Zhang X T | 1999 | J Mater Process Tech1999，85，： | 1 |
| 17 | Modified generalized Lorenz system and fold chaotic attractors显示文摘 | Bao B C Liu Z Yu J B | 2009 | International Journal of Bifurcation and Chaos2009，19，8： | 1 |
| 18 | Heat stress injury in relation to membrance lipid peroxidation in creeping bentgrass 显示文摘 | Liu X Z Huang B R | 2000 | Crop Sci2000，40，： | 1 |
| 19 | Synthesis of BiYO3 for degradation of organic compounds under visible light irradiation显示文摘 | Qin Z Z Liu Z L Liu Y B | 2009 | Catalysis Communications2009，10，12： | 1 |
| 20 | Induction of microRNA-155 during Heli- cobacter pylori infection and its negative regulatory role in the inflam- matory response 显示文摘 | Xiao B Liu Z Li B S | 2009 | J Infect Dis2009，200，6： | 1 |
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