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| 1 | Association of telomere length with authentic pluripotency of ES/iPS cells显示文摘Telomerase 和 telomeres 为干细胞的不定的复制是重要的。最近,体的房间的 telomeres 被发现是 reprogrammed 在导致的 pluripotent 干细胞(iPSCs ) 伸长。然而,在在胚胎的干细胞(转换字符) 或 iPSCs 的 vivo 的发展 pluripotency 的 telomeres 的角色直接没被探讨。我们证明有长 telomeres 的转换字符展出真发展 pluripotency,由完全的转换字符小狗以及 germline 能干的怪物的产生证实了在啮齿类动物可得到的最紧的测试。有短 telomeres 的转换字符显示出减少的 teratoma 形成和怪物生产,并且没能产生完全的转换字符小狗。Telomere 长度高度被相关(r > 0.8 ) 与转换字符的发展 pluripotency。短 telomeres 减少 proliferative 率或转换字符的能力,改变与 telomere epigenetics 有关的基因的表示,为 embryogenesis 重要的下面调整基因并且破坏细菌房间区别。而且,有更长的 telomeres 的 iPSCs 与短 telomeres 比那些与更高的效率产生怪物。我们功能的 telomeres 为 ESCs/iPSCs 的发展 pluripotency 是必要的并且建议那 telomere 长度可以提供一个珍贵标记评估干细胞 pluripotency 的数据表演,特别地当紧测试不是可行的时。 | Junjiu Huang Fang Wang Maja Okuka Na Liu Guangzhen Ji Xiaoying Ye Bingfeng Zuo Minshu Li Ping Liang William W Ge John CM Tsibris David L Keefe Lin Liu | 2011 | Cell Research2011，21，5： | 3 |
| 2 | Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis显示文摘 | Phil A Hart Terumi Kamisawa William R Brugge Jae Bock Chung Emma L Culver László Czakó Luca Frulloni Vay Liang W Go Thomas M Gress Myung-Hwan Kim Shigeyuki Kawa Kyu Taek Lee Markus M Lerch Wei-Chih Liao Matthias L?hr Kazuichi Okazaki Ji Kon Ryu Nicolas Sc | 2013 | Gut2013，，12： | 2 |
| 3 | Adjuvant intraportal venous chemotherapy for patients with hepatocellular carcinoma and portal vein tumor thrombi following hepatectomy plus portal thrombectolny 显示文摘 | Liang L J Hu W J Yin X Y | 2008 | World J Surg2008，32，4： | 1 |
| 4 | DEA models for supply chain efficiency evaluation显示文摘 | Liang L Feng Y Cook W D Zhu J | 2006 | Annals of Operations Research2006，145，1： | 1 |
| 5 | Optimal resource allocation for multiuser MIMO-OFDM systems with user rate constraints显示文摘 | Ho Winston W L Liang Yingchang | 2009 | IEEE Transactions on Vehicular Technology2009，58，3： | 1 |
| 6 | Organizational decision support system for effective R&D project selection 显示文摘 | TIAN Q MA J LIANG J RON C W K OU L | 2005 | Decision Support Systems2005，39，3： | 1 |
| 7 | Cytochrome P450 family member CYP704B2 catalyzes the omega } - hydrnxylation of fatty acids and is required for anther cutin biosynthesis and pollen exine formation in rice 显示文摘 | Li H Pinot F Sauveplane V Werck-Reichhart D Diehl P Schreiber L Franke R Zhang P Chert L Gao Y Liang W ZhangD | 2010 | Plant Cell2010，22，1： | 1 |
| 8 | Multifunctional cyclotriphosphazene/hexagonal boron nitride hybrids and their flame retarding bismaleimide resins with high thermal conductivity and thermal stability显示文摘 | Jin W Q Yuan L Liang G Z | 2014 | ACS Appl Mater&Interfaces2014，6，14： | 1 |
| 9 | Effects of simVastatin femoral fracture healing in rats显示文摘 | Liang C Y Zhang L Zhao W G | 2006 | J Fourth Mil Med Univ2006，27，3： | 1 |
| 10 | Ramipril improves oxida-tive stress-related vascular endothelial dysfunction in db/dbmice显示文摘 | LIANG W TAN CY ANG L | 2008 | J Physiol Sci2008，58，6： | 1 |
| 11 | A robust objectsegmentation system using a probability-based back-ground extraction algorithm显示文摘 | CHIU CH CH KU M Y LIANG L W | 2010 | IEEE Transactions onCircuits and Systems or Video Technology2010，20，4： | 1 |
| 12 | Common reservoirs for Peni-cillium marneffei infection in humans and rodents, China 显示文摘 | Cao C Liang L Wang W | 2011 | Emerg Infect Dis2011，17，2： | 1 |
| 13 | Proteomic analysis of strawberry leaves infected with Colletotrichum fragariae显示文摘 | Fang X P Chen W Y Xin Y Hengmu Z Chengqi Y Hong Y Hui L Wenfei X Shuzhen W Guizhen Z Hongbo L Liang J Huasheng M Songlin R | 2012 | Journal of proteomics2012，75，： | 1 |
| 14 | Integrated leakage detection and localization model for gas pipelines based on the acoustic wave method显示文摘 | JIN H ZHANG L B LIANG W | 2014 | Journal of Loss Prevention in the Process Industries2014，27，： | 1 |
| 15 | The North American spine society lumbar spine outcome assessment instrument:reliability and validity tests显示文摘 | Dahroy L H Cats-Baril W L Katz J N Fossel A H Liang M H | 1996 | Spine1996，21，： | 1 |
| 16 | Solid polymer electrolytes,2:Preparation and ionic conductivity of solid polymer electrolytes based on segmented polysiloxane-modified polyurethane显示文摘 | KUO P L LIANG W J LIN C L | 2002 | Macromol Chem Phys2002，203，： | 1 |
| 17 | Stability of a biological tissue fixed with a naturally occurring crosslinking agent (genipin) 显示文摘 | Sung H W Liang I L Chen C N | 2001 | J Biomed Mater Res2001，55，： | 1 |
| 18 | A modified super-efficiency DEA model for infeasibility 显示文摘 | Cook W D Liang L Zha Y | 2009 | J Oper Res Soc2009，60，2： | 1 |
| 19 | Alternative secondary goals in DEA cross efficiency evaluation 显示文摘 | Liang L Wu J Cook W D | 2008 | International Journal of Production Economics2008，113，10： | 1 |
| 20 | Acute decompensated heart failure and the cardiorenal syndrome显示文摘 | LIANG K V WILLIAMS A W GREENE E L | 2008 | Crit Care Med2008，，： | 1 |
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