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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009，7，4： | 3 |
| 3 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 4 | Two algorithms for constructing a delaunay triangulation显示文摘 | Lee D T Schacheer B J | 1980 | International Journal of Computer and Information Science1980，9，1： | 2 |
| 5 | The potential role of resistin in atherogenesis 显示文摘 | BURNETT M S LEE C W KINNAIRD T D | 2005 | Atherosclerosis2005，182，： | 1 |
| 6 | Effects of thermal and chemical surface-flame interaction on flame quenching显示文摘 | KIM K T LEE D H KWON S | 2006 | Combust and Flame2006，146，： | 1 |
| 7 | Characteristics of nitrile--butadiene rubber layered silicate nanocomposites with silane coupling agent 显示文摘 | Kim J T Lee D Y Oh T S | 2003 | J Appl Polym Sci2003，89，10： | 1 |
| 8 | Characterization and distribution of metals in surficial sediments in Sontheastern Taiwan显示文摘 | Lee C L Fang M D Hsich M T | 1998 | Marine Pollution Bulletin1998，36，6： | 1 |
| 9 | A comparative illustration of AI plmming-based Web services composition 显示文摘 | OH S C LEE D W KUMARA S R T | 2006 | ACM SlGecom Exchanges2006，5，5： | 1 |
| 10 | Astrocytes and epilepsy 显示文摘 | De-Lanerolle N C Lee T S Spencer D D | 2010 | Neurotherapeutics2010，7，4： | 1 |
| 11 | Integrity of complex shape product by powder injection molding 显示文摘 | HENS K F LEE D LIN S T | 1991 | Powder Metallurgy International1991，23，1： | 1 |
| 12 | Effect of heat treatment path on the cold formability of drawn dual-phase steels 显示文摘 | Park K S Park K T Lee D L | 2007 | Materials Science and Engineering : A2007，，： | 1 |
| 13 | Endocytic delivery of lipocalin- siderophore-iron complex rescues the kidney from isehemia-reper- fusion injury显示文摘 | Moil K Lee H T Rapoport D | 2005 | J Clin Invest2005，115，3： | 1 |
| 14 | Deformation and annealing textures of silver wire显示文摘 | Shin H J Jeong H T Lee D N | 2000 | Materials Science and Engineering A2000，279，： | 1 |
| 15 | Spatially continuous six degree of freedom position and orientation sensor 显示文摘 | LEE D KEVIN E ANDREW T | 1999 | Sensors Review1999，19，2： | 1 |
| 16 | Sludge chemical composition changes under uni-directional freezing 显示文摘 | Huang W T Chang I L Lee D J | 1996 | Water Science and Technology1996，34，34： | 1 |
| 17 | New constraints on the sources and behavior of neodymium and hafnium in seawater from Pacific Ocean ferromanganese crusts显示文摘 | VAN DE FLIERDT T FRANK M LEE D C | 2004 | Geochim et Cosmochim Acta2004，68，19： | 1 |
| 18 | Application of quasicrystalline particles as a strengthening phase in Mg-Zn-Y alloys 显示文摘 | Bae D H Lee M H Kim K T | 2002 | Journal of Alloys and Com- pouds2002，342，： | 1 |
| 19 | Pervaporation of trace chlorinated organics from water through irradiated polyethylene membrane 显示文摘 | Lee G T Krovvidi K R Greenberg D B | 1989 | J Membrane Sci1989，47，： | 1 |
| 20 | A genetic linkage map of a cichlid fish, the tilapia (Oreochromis niloticus) 显示文摘 | Kocher T D Lee W J Sobolewska H etal | 1998 | Genetics1998，148，： | 1 |
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