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| 1 | Conservation needs of amphibians in China: A review显示文摘The conservation status of all the amphibians in China is analyzed,and the country is shown to be a global priority for conservation in comparison to many other countries of the world.Three Chinese regions are particularly rich in amphibian diversity:Hengduan,Nanling,and Wuyi mountains.Sala-manders are more threatened than frogs and toads.Several smaller families show a high propensity to become seriously threatened:Bombinatoridae,Cryptobranchidae,Hynobiidae and Salamandridae.Like other parts of the world,stream-breeding,high-elevation forest amphibians have a much higher likeli-hood of being seriously threatened.Habitat loss,pollution,and over-harvesting are the most serious threats to Chinese amphibians.Over-harvesting is a less pervasive threat than habitat loss,but it is more likely to drive a species into rapid decline.Five conservation challenges are mentioned with recommendations for the highest priority research and conservation actions. | Michael Wai Neng LAU Simon N STUART Janice S CHANSON Neil A COX Debra L FISCHMAN | 2007 | Science China(Life Sciences)2007，50，2： | 12 |
| 2 | Randomised controlled trial comparing modified Sano's and narrow band imaging international colorectal endoscopic classifications for colorectal lesions显示文摘AIM To assess the utility of modified Sano′s(MS) vs thenarrow band imaging international colorectal endoscopic(NICE) classification in differentiating colorectal polyps.METHODS Patients undergoing colonoscopy between 2013 and 2015 were enrolled in this trial.Based on the MS or the NICE classifications,patients were randomised for real-time endoscopic diagnosis.This was followed by biopsies,endoscopic or surgical resection.The endoscopic diagnosis was then compared to the final(blinded) histopathology.The primary endpoint was the sensitivity(Sn),specificity(Sp),positive predictive value(PPV) and negative predictive value(NPV) of differentiating neoplastic and non-neoplastic polyps(MSⅡ/Ⅱo/Ⅲa/Ⅲb vs I or NICE 1 vs 2/3).The secondary endpoints were 'endoscopic resectability'(MSⅡ/Ⅱo/Ⅲa vs Ⅰ/Ⅲb or NICE 2 vs 1/3),NPV for diminutive distal adenomas and prediction of post-polypectomy surveillance intervals.RESULTS A total of 348 patients were evaluated.The Sn,Sp,PPV and NPV in differentiating neoplastic polyps from non-neoplastic polyps were,98.9%,85.7%,98.2% and 90.9% for MS;and 99.1%,57.7%,95.4% and 88.2% for NICE,respectively.The area under the receiver operating characteristic curve(AUC) for MS was 0.92(95%CI:0.86-0.98);and AUC for NICE was 0.78(95%CI:0.69,0.88).The Sn,Sp,PPV and NPV in predicting 'endoscopic resectability' were 98.9%,86.1%,97.8% and 92.5% for MS;and 98.6%,66.7%,94.7% and 88.9% for NICE,respectively.The AUC for MS was 0.92(95%CI:0.87-0.98);and the AUC for NICE was 0.83(95%CI:0.75-0.90).The AUC values were statistically different for both comparisons(P = 0.0165 and P = 0.0420,respectively).The accuracy for diagnosis of sessile serrated adenoma/polyp(SSA/P) with high confidence utilizing MS classification was 93.2%.The differentiation of SSA/P from other lesions achieved Sp,Sn,PPV and NPV of 87.2%,91.5%,89.6% and 98.6%,respectively.The NPV for predicting adenomas in diminutive rectosigmoid polyps(n = 150) was 96.6% and 95% with MS and NICE respectively.The calculated accuracy of post-polypectomy surveillance for MS group was 98.2%(167 out of 170) and for NICE group was 92.1%(139 out of 151).CONCLUSION The MS classification outperformed the NICE classification in differentiating neoplastic polyps and predicting endoscopic resectability.Both classifications met ASGE PIVI thresholds. | Leonardo Zorrón Cheng Tao Pu Kuan Loong Cheong Doreen Siew Ching Koay Sze Pheh Yeap Amanda Ovenden Mahima Raju Andrew Ruszkiewicz Philip W Chiu James Y Lau Rajvinder Singh | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，9： | 4 |
| 3 | Global Nanoteehnology Research Literature Overview显示文摘 | Kostoff R N Koytcheff R G Lau C G Y | 2007 | Current Science2007，，11： | 1 |
| 4 | Size distributions of maternal and fetal DNA in maternal plasma显示文摘 | Chan K C ZhangJ Hui A B Wong N Lau T K Leung T N | 2004 | Clin Chem2004，50，： | 1 |
| 5 | High level expression of hepatitis B viral antigens in fibrosing cholestatic hepatitis 显示文摘 | Lau J Y N Davis GL Bain V G | 1992 | Gastroenterology1992，102，： | 1 |
| 6 | Remote sea surface variations during ENSO: evidence for a tropical atmospheric bridge显示文摘 | KLEIN S A SODEN B J LAU N C | 1999 | J Clim1999，12，： | 1 |
| 7 | A comparative study on catalyst deactivation of nickel and cobalt incorporated MCM-41 catalysts modified by platinum in methane reforming with carbon dioxide 显示文摘 | LIU D P CHEO W N E LIM Y W Y BORGN A LAU R YANG Y H | 2010 | Catalysis Today2010，154，34： | 1 |
| 8 | Natural inter feron α/β-producing cells link innate and adaptive immunity显示文摘 | Kadowaki N Antonenko S Lau JY | 2000 | J ExpMed2000，192，2： | 1 |
| 9 | Innovative laboratory testing显示文摘 | Lau J S O Chandler N A | 2004 | International Journal of Rock Mechanics and Mining Sci-ences2004，41，8： | 1 |
| 10 | Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs显示文摘 | Lim L P Lau N C Garrett-Engele P | | 0，，7027： | 1 |
| 11 | Hierarchi-cal radio resource optimization for heterogeneous networkswith enhanced inter-cell interference coordination(eICIC) 显示文摘 | Liu An Lau V K N Ruan Liangzhong | 2014 | IEEE Transactions on Signal Processing2014，62，： | 1 |
| 12 | Melt strength ofpolypropylene : its relevance to thermoforming 显示文摘 | LAU H C BHATACHARYA S N FIELD G J | 1998 | PolymerEngineering Science1998，38，11： | 1 |
| 13 | Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice显示文摘 | Ji C Kaplowitz N Lau MY | 2011 | Hepatology2011，54，1： | 1 |
| 14 | Managing realtime database transactions in mobile ad-hoc networks显示文摘 | Le Gruenwald Shankar M Banik Chuo N Lau | 2007 | Distributed and Parallel Database2007，22，1： | 1 |
| 15 | Channel capacity and error exponents of variable rate adaptive channel coding for Rayleigh fading channels显示文摘 | LAU V K N | 1999 | IEEE Trans Commun1999，47，9： | 1 |
| 16 | S-allyl cysteine reduces oxidant load in cells involved in the atherogenic process显示文摘 | Ho SE Ide N Lau BH | 2001 | Phytomedicine2001，8，1： | 1 |
| 17 | Deletion of the re- ceptor for advanced glycation end products reduces glomer- ulosclerosis and preserves renal function in the diabetic OVE26 mouse 显示文摘 | Reiniger N Lau K Mccalla D | 2010 | Diabetes2010，59，： | 1 |
| 18 | Optimal energy scheduling for residential smart grid with centralized renewable energy source显示文摘 | Wu Y Lau V K N Tang D H K | 2014 | Systems Journal IEEE2014，8，2： | 1 |
| 19 | Modulation format iden- tification in heterogeneous fiber-optic networks using arti- ficial neural networks显示文摘 | Khan F N Zhou Y Lau A P | 2012 | Optics Express2012，20，12： | 1 |
| 20 | The observed structure of tropospheric stationary waves and the local balances of vorticity and heat显示文摘 | LAU N C | 1979 | J Atmos Sci1979，36，6： | 1 |
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