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    题名 作者 年代 出处 被引量
1Metabolic effects of fructose显示文摘LêKA L T 2006Curr Opin Clin Nutr Metab Care2006,9,4:1
2Iron and copper chelation by flavonoids:an electrospray mass spectrometry study显示文摘Fernandez M T Mira M L Florêncio M H 0,,02:1
3Overview of differential equations with non-standard growth显示文摘Petteri Harjulehto Peter H?st? út V. Matti Nuortio 2010Nonlinear Analysis2010,,12:1
4Universal newborn hearing screening in the Champagne-Ardenne region:a 4-year follow up after early diagnosis of hearing impairment显示文摘Lagnagne T Lévêque M Schmidt P 2010Int J Pediatr Otorhinolaryngol2010,74,10:1
5Universal newborn hearing screening in the Champagne-Ardenne region:a 4-year follow-up after early diagnosis of hearing impairment显示文摘Langagne T Lévêque M Schmidt P 2010Int J Pediatr Otorhinolaryngol2010,74,10:1
6Large-eddy simulation of a compressible flow in a three-dimensional open cavity at high Reynolds number显示文摘LARCHEVêQUE L SAGAUT P LE T H 2004Journal of Fluid Mechanics2004,516,:1
7Constipation in children with isolated overactive bladders显示文摘Veiga M L Lordêlo P Farias T 2013J Pediatr Urol2013,9,6:1
8Biliary complications after livern transplantation:addition of T1-weighted images toMRcholangiopancreatography facilitates detectionof cast inbiliary cast syndrome显示文摘K i n n e r S U m u t l u L D e c h ê n e A e t a l 2012Radiology2012,263,2:1
9In the QTL region surrounding porcine MHC, gene order is conserved with human genome显示文摘Carine Genêt Christine Renard Cédric Cabau Claire Rogel-Gaillard Jo?l Gellin Denis Milan 2001Mammalian Genome2001,,3:1
10Expression and purification of untagged full-length HCV NS5B RNA-dependent RNA polymerase显示文摘Wang Q M Johnson R B Chen D Lévêque V J Ren J Hockman M A Abe K Hachisu T Kond 0,,02:1
11Cathepsin D expression by cancer and stromal cells in breast cancer: an immunohistochemical study of 1348 cases显示文摘Bernard Têtu Jacques Brisson Hélène Lapointe Chang Shu Wang Pascale Bernard Caty Blanchette 1999Breast Cancer Research and Treatment1999,,2:1
12Bladder Tumor Infiltrating Mature Dendritic Cells and Macrophages as Predictors of Response to Bacillus Calmette-Guérin Immunotherapy显示文摘Cherifa Ayari Hélène LaRue Hélène Hovington Marc Decobert Fran?ois Harel Alain Bergeron Bernard Têtu Louis Lacombe Yves Fradet 2009European Urology2009,,6:1
13Characterization of a panel of Vietnamese rice varieties using DArT and SNP markers for association mapping purposes显示文摘PhungN T P Mai C D Mournet P Frouin J Droc G Ta1 N K Jouannic S Lê L T Do V N Gantet P Courtois B 2014BMC Plant Biology2014,14,:1
14Bladder Tumor Infiltrating Mature Dendritic Cells and Macrophages as Predictors of Response to Bacillus Calmette-Guérin Immunotherapy显示文摘Cherifa Ayari Hélène LaRue Hélène Hovington Marc Decobert Fran?ois Harel Alain Bergeron Bernard Têtu Louis Lacombe Yves Fradet 2009European Urology2009,,6:1
15Genetic analysis of the biosynthesis of 2-methoxy-3-isobutylpyrazine,a major grape-derived aroma compound impacting wine quality显示文摘GUILLAUMIE S IIG A RéTY S BRETTE M TROSSAT-MAGNIN C DECROOCQ S LéON C KEIME C YE T BALTEN-WECK-GUYOT R CLAUDEL P BORDENAVE L VANBRA-BANT S DUCHêNE E DELROT S DARRIET P HUGUENEYP GOMèS E 2013Plant Physiology2013,162,2:1
16Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles显示文摘The cells of origin of neurogenic heterotopic ossifications(NHOs), which develop frequently in the periarticular muscles following spinal cord injuries(SCIs) and traumatic brain injuries, remain unclear because skeletal muscle harbors two progenitor cell populations: satellite cells(SCs), which are myogenic, and fibroadipogenic progenitors(FAPs), which are mesenchymal. Lineage-tracing experiments using the Cre recombinase/Lox P system were performed in two mouse strains with the fluorescent protein Zs Green specifically expressed in either SCs or FAPs in skeletal muscles under the control of the Pax7 or Prrx1 gene promoter, respectively. These experiments demonstrate that following muscle injury, SCI causes the upregulation of PDGFRα expression on FAPs but not SCs and the failure of SCs to regenerate myofibers in the injured muscle, with reduced apoptosis and continued proliferation of muscle resident FAPs enabling their osteogenic differentiation into NHOs. No cells expressing Zs Green under the Prrx1 promoter were detected in the blood after injury, suggesting that the cells of origin of NHOs are locally derived from the injured muscle. We validated these findings using human NHO biopsies. PDGFRα+mesenchymal cells isolated from the muscle surrounding NHO biopsies could develop ectopic human bones when transplanted into immunocompromised mice, whereas CD56+myogenic cells had a much lower potential. Therefore, NHO is a pathology of the injured muscle in which SCI reprograms FAPs to undergo uncontrolled proliferation and differentiation into osteoblasts.Hsu-Wen Tseng Dorothée Girard Kylie A.Alexander Susan M.Millard Frédéric Torossian Adrienne Anginot Whitney Fleming Jules Gueguen Marie-Emmanuelle Goriot Denis Clay Beulah Jose Bianca Nowlan Allison R.Pettit Marjorie Salga François Genêt Marie-Caroline Le Bousse-Kerdilès Sébastien Banzet Jean-Pierre Lévesque 2022Bone Research2022,10,2:0
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