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| 1 | 闭环式管理:从战略到运营显示文摘平衡计分卡创始人罗伯特·卡普兰和戴维·诺顿建立了一个闭环式的管理体系,将战略和运营结合起来,并为每个阶段提供了各种工具。 | 罗伯特·卡普兰(Robert S. Kaplan) 戴维·诺顿(David P. Norton) 章程(翻译) | 2008 | 商业评论2008,,2: | 32 |
| 2 | STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation显示文摘 | Wanqiang Sheng Fan Yang Yi Zhou Henry Yang Pey Yng Low David Michael Kemeny Patrick Tan Akira Moh Mark H Kaplan Yongliang Zhang Xin-Yuan Fu | 2014 | Cell Research2014,24,12: | 7 |
| 3 | Porosity of 3D biomaterial scaffolds and osteogenesis显示文摘 | Vassilis Karageorgiou David Kaplan | 2005 | Biomaterials2005,,27: | 4 |
| 4 | The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase显示文摘 | Thomas F Franke Sung-Il Yang Tung O Chan Ketaki Datta Andrius Kazlauskas Deborah K Morrison David R Kaplan Philip N Tsichlis | 1995 | Cell1995,,5: | 2 |
| 5 | Management of the Open Abdomen: From Initial Operation to Definitive Closure显示文摘 | Vargo Daniel Richardson J David Campbell Andre Chang Michael Fabian Timothy Franz Michael Kaplan Mark Moore Frederick Reed R Lawrence Scott Bradford Silverman Ronald | 2009 | The American Surgeon2009,,11: | 2 |
| 6 | Do statins reduce hepatitis C RNA titers during routine clinical use?显示文摘AIM: To compare hepatitis C virus (HCV) titers in patients with chronic hepatitis C with and without exposure to 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins).METHODS: Medical records were reviewed for 6463 patients with documented HCV infection at a single center between March 2004 and September 2006. Patients with confi rmed viremia and meeting inclusion criteria were assigned to one of three groups: Group A (n = 50), dyslipidemic patients with statin usage during HCV RNA polymerase chain reaction (PCR) determination; Group B (n = 49), dyslipidemic patients with prior or future statin usage but not at the time of HCV RNA PCR determination; and Group C (n = 102), patients without statin usage during the study period. The primary analysis explored the effect of statin therapy on HCV viremia. Secondary analyses assessed class effect, dose response, and effect of other lipid-lowering therapies on HCV viral titers.RESULTS: Median HCV RNA titers did not signif icantly differ among the three groups (Group A: 4 550 000 IU/mL, Group B: 2 850 000 IU/mL, Group C: 3 055 000 IU/mL).For those subjects with longitudinal assessment of HCV viremia prior to and while on statins, there were no signif icant differences between pre- and post-HCV viral titers. Additionally, no differences in HCV titers were observed at any dose level of the most prescribed statin, simvastatin. However, hypertriglyceridemia independently correlated with HCV titers, and niacin exposure was associated with signif icantly lower viral titers (P < 0.05).CONCLUSION: There was no apparent effect of statins on HCV viral replication in this analysis. Further investigation is warranted to explore the possible antiviral properties of triglyceride-lowering agents and their potential role as adjuncts to standard HCV therapy. | Kimberly A Forde Connie Law Rose O’Flynn David E Kaplan | 2009 | World Journal of Gastroenterology2009,15,40: | 2 |
| 7 | Restore or retreat? Saltwater intrusion and water management in coastal wetlands显示文摘Coastal wetlands perform a unique set of physical,chemical,and biological functions,which provide billions of dollars of ecosystem services annually.These wetlands also face myriad environmental and anthropogenic pressures,which threaten their ecological condition and undermine their capacity to provide these services.Coastal wetlands have adapted to a dynamic range of natural disturbances over recent millennia,but face growing pressures from human population growth and coastal development.These anthropogenic pressures are driving saltwater intrusion(SWI)in many coastal systems.The position of coastal wetlands at the terrestrial-marine interface also makes them vulnerable to increasing rates of sealevel rise and changing climate.Critically,anthropogenic and natural stressors to coastal wetlands can act synergistically to create negative,and sometimes catastrophic,consequences for both human and natural systems.This review focused on the drivers and impacts of SWI in coastal wetlands and has two goals:(1)to synthesize understanding of coastal wetland change driven by SWI and(2)to review approaches for improved water management to mitigate SWI in impacted systems.While we frame this review as a choice between restoration and retreat,we acknowledge that choices about coastal wetland management are context-specific and may be confounded by competing management goals.In this setting,the choice between restoration and retreat can be prioritized by identifying where the greatest return in ecosystem services can be achieved relative to restoration dollars invested.We conclude that restoration and proactive water management is feasible in many impacted systems. | Elliott White,Jr. David Kaplan | 2017 | Ecosystem Health and Sustainability2017,3,1: | 2 |
| 8 | Dynamic conjugate F-SHARP microscopy显示文摘Optical microscopy is an indispensable tool in biomedical sciences,but its reach in deep tissues is limited due to aberrations and scattering.This problem can be overcome by wavefront-shaping techniques,albeit at limited fields of view(FOVs).Inspired by astronomical imaging,conjugate wavefront shaping can lead to an increased field of view in microscopy,but this correction is limited to a set depth and cannot be dynamically adapted.Here,we present a conjugate wavefront-shaping scheme based on focus scanning holographic aberration probing(F-SHARP).We combine it with a compact implementation that can be readily adapted to a variety of commercial and home-built two-photon microscopes.We demonstrate the power of the method by imaging with high resolution over extended FOV(>80μm)deeper than 400μm inside a mouse brain through a thinned skull. | Ioannis N.Papadopoulos Jean-Sebastien Jouhanneau Naoya Takahashi David Kaplan Matthew Larkum James Poulet Benjamin Judkewitz | 2020 | Light(Science & Applications)2020,9,1: | 2 |
| 9 | Silk fibroin microtubes for blood vessel engineering显示文摘 | Michael Lovett Christopher Cannizzaro Laurence Daheron Brady Messmer Gordana Vunjak-Novakovic David L. Kaplan | 2007 | Biomaterials2007,,35: | 2 |
| 10 | Bone Tissue Engineering Using Human Mesenchymal Stem Cells: Effects of Scaffold Material and Medium Flow显示文摘 | Lorenz Meinel Vassilis Karageorgiou Robert Fajardo Brian Snyder Vivek Shinde-Patil Ludwig Zichner David Kaplan Robert Langer Gordana Vunjak-Novakovic | 2004 | Annals of Biomedical Engineering2004,,1: | 2 |
| 11 | Silkbased biomaterials显示文摘 | FRANK Diaz DAVID L Kaplan | 2003 | Biomaterials2003,,24: | 1 |
| 12 | Transforming the balanced scorecard from performance measurement to strategic management显示文摘 | Norton David P | 2001 | Harvard Business Review2001,15,2: | 1 |
| 13 | Silk-based biomaterials显示文摘 | Gregory H Altman Frank Diaz Caroline Jakuba Tara Calabro Rebecca L Horan Jingsong Chen Helen Lu John Richmond David L Kaplan | 2002 | Biomaterials2002,,3: | 1 |
| 14 | A silk-based scaffold platform with tunable architecture for engineering critically-sized tissue constructs显示文摘 | Lindsay S. Wray Jelena Rnjak-Kovacina Biman B. Mandal Daniel F. Schmidt Eun Seok Gil David L. Kaplan | 2012 | Biomaterials2012,,36: | 1 |
| 15 | Porous 3-D scaffolds from regenerated silk fibroin显示文摘 | Jin Hyoung-Joon Kaplan David L | 2004 | Biomacromolecules2004,5,3: | 1 |
| 16 | The balance score card measures that drive performance 显示文摘 | Robert S Kaplan David P Norton | 1992 | Harvard Business Re-view1992,,: | 1 |
| 17 | Postoperative Complications Following Colectomy for Ulcerative Colitis in Children显示文摘 | Ing Shian Soon Iwona Wrobel Jennifer C.C. deBruyn Reg Sauve David L. Sigalet Belle S. Kaplan Marie-Claude Proulx Gilaad G. Kaplan | 2012 | Journal of Pediatric Gastroenterology and Nutrition2012,,6: | 1 |
| 18 | The balanced scorecard:measures that drive performance显示文摘 | David P Norton | 1992 | Harvard Business Review1992,70,1: | 1 |
| 19 | The balanced score card measures that drive performance显示文摘 | Robert S kaplan David P Norton | 1992 | Harvard Business Review1992,,12: | 1 |
| 20 | Supporting public availability and accessibility with Elvin : Experiences and reflections 显示文摘 | FITZPATRICK G KAPLAN S MANSFIELD T DAVID A SEGALL B | 2002 | Computer Supported Cooperative Work2002,11,3: | 1 |