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| 1 | CT diagnosis of recurrence after pancreatic cancer:Is there a pattern?显示文摘AIM:To investigate predilection sites of recurrence of pancreatic cancer by computed tomography(CT)in follow-up after surgery. METHODS:Seventy seven patients with recurrence after pancreatic cancer surgery were retrospectively identified.The operative technique,R-status,T-stage and development of tumor markers were evaluated. Two radiologists analyzed CT scans with consensus readings.Location of local recurrence,lymph node recurrence and organ metastases were noted.Surgery and progression of findings on follow-up CT were con-sidered as reference standard. RESULTS:The mean follow-up interval was 3.9± 1.8 mo,with a mean relapse-free interval of 12.9± 10.4 mo.The predominant site of recurrence was local (65%),followed by lymph node(17%),liver metastasis (11%)and peritoneal carcinosis(7%).Local recurrence emerged at the superior mesenteric artery(n=28),the hepatic artery(n=8),in an area defined by the surrounding vessels:celiac trunk,portal vein,inferior vena cava(n=22),and in a space limited by the mesenteric artery,portal vein and inferior vena cava(n=17). Lymph node recurrence occurred in the mesenteric root and left lateral to the aorta.Recurrence was confirmed by surgery(n=22)and follow-up CT(n=55).Tumor markers[carbohydrate antigen 19-9(CA19-9),carcinoembryonic antigen(CEA)]increased in accordance with signs of recurrence in most cases(86%CA19-9;79.2% CEA). CONCLUSION:Specific changes of local and lymph node recurrence can be found in the course of the cardinal peripancreatic vessels.The superior mesenteric artery is the leading structure for recurrence. | Tobias Heye Nicola Zausig Miriam Klauss Reinhard Singer Jens Werner Gtz Martin Richter Hans-Ulrich Kauczor Lars Grenacher | 2011 | World Journal of Gastroenterology2011,17,9: | 6 |
| 2 | Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties显示文摘 | Sarah Schwitalla Alexander A. Fingerle Patrizia Cammareri Tim Nebelsiek Serkan I. G?ktuna Paul K. Ziegler Ozge Canli Jarom Heijmans David J. Huels Guenievre Moreaux Rudolf A. Rupec Markus Gerhard Roland Schmid Nick Barker Hans Clevers Roland Lang Jens Neu | 2013 | Cell2013,,: | 3 |
| 3 | Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology显示文摘 | Sibylle A. Kozek-Langenecker Arash Afshari Pierre Albaladejo Cesar Aldecoa Alvarez Santullano Edoardo De Robertis Daniela C. Filipescu Dietmar Fries Klaus G?rlinger Thorsten Haas Georgina Imberger Matthias Jacob Marcus Lancé Juan Llau Sue Mallett Jens Mei | 2013 | European Journal of Anaesthesiology2013,,6: | 3 |
| 4 | Antibiotic-loaded phosphatidylcholine inhibits staphylococcal bone infection显示文摘AIM: To test antibiotic-loaded coating for efficacy in reducing bacterial biofilm and development of osteomyelitis in an orthopaedic model of implant infection. METHODS: Phosphatidylcholine coatings loaded with 25% vancomycin were applied to washed and sterilized titanium wires 20 mm in length. A 10 mm segment was removed from rabbit radius(total = 9; 5 coated, 4 uncoated), and the segment was injected with 1 × 106 colony forming units(CFUs) of Staphylococcus aureus(UAMS-1 strain). Titanium wires were inserted throughthe intramedullary canal of the removed segment and into the proximal radial segment and the segment was placed back into the defect. After 7 d, limbs were removed, X-rayed, swabbed for tissue contamination. Wires were removed and processed to determine attached CFUs. Tissue was swabbed and streaked on agar plates to determine bacteriological score.RESULTS: Antibiotic-loaded coatings resulted in significantly reduced biofilm formation(4.7 fold reduction in CFUs; P < 0.001) on titanium wires and reduced bacteriological score in surrounding tissue(4.0 ± 0 for uncoated, 1.25 ± 0.5 for coated; P = 0.01). Swelling and pus formation was evident in uncoated controls at the 7 d time point both visually and radiographically, but not in antibiotic-loaded coatings.CONCLUSION: Active antibiotic was released from coated implants and significantly reduced signs of osteomyelitic symptoms. Implant coatings were well tolerated in bone. Further studies with additional control groups and longer time periods are warranted. Antibiotic-loaded phosphatidylcholine coatings applied at the point of care could prevent implant-associated infection in orthopaedic defects. | Jessica Amber Jennings Karen E Beenken Robert A Skinner Daniel G Meeker Mark S Smeltzer Warren O Haggard Karen S Troxel | 2016 | World Journal of Orthopedics2016,7,8: | 2 |
| 5 | A simple fast hybrid pattern-matching algorithm 显示文摘 | FRANEK F JENNINGS C G SMYTH P W F | 2007 | Journal of Discrete Algorithms2007,4,5: | 1 |
| 6 | Clinical spectrum of epi- sodic ataxia type 2 显示文摘 | Jen J Kim G W Baloh R W | 2004 | Neurology2004,62,1: | 1 |
| 7 | Agricultural women in Central Queensland and changing modes of production: a preliminary exploration of the issues显示文摘 | Jennings G Stehlik D | 2000 | Rural Society2000,10,1: | 1 |
| 8 | Hyperm-ethylation-associated inactivation indicates atumor supperessor role for p15显示文摘 | HERMAN J G JEN J MERLO A | 1996 | Cancer Res1996,56,: | 1 |
| 9 | Carabid beetles (Coleoptera: Carabidae) associated with strip clearcut and dense spruce-fir forests of Maine显示文摘 | JENNINGS D T HOUSEWEART M W DUNN G A | 1986 | The Coleopterists Bulletin1986,40,3: | 1 |
| 10 | Exploring tourists' environmental learning, values and travel experiences in relation to climate change: A postmodern constructivist research agenda 显示文摘 | Kachel U E Jennings G R | 2010 | Tourism & Hospitality Research2010,10,2: | 1 |
| 11 | Myocardialnecrosis induced by temporary occlusion of coronary atery in the dog 显示文摘 | Jennings R B Sommers H M Smyth G A | 1960 | Arch Pathol1960,70,1: | 1 |
| 12 | Design and implementation of ejector driven micropump显示文摘 | Chuech S G Chuan Chih Chen Jen Chih Lu | 2007 | Energy Conversion and Management2007,48,: | 1 |
| 13 | Machine vision and intelligence incorporating motion control显示文摘 | Jennings R B Bright G | 1999 | Assembly Automation1999,19,1: | 1 |
| 14 | Aerosol light absorption in the North Atlantic:Trends and seasonal characteristics during the period 1989 to 2003显示文摘 | Junker C Jennings S G Cachier H | 2006 | Atmos Chem Phys2006,6,2: | 1 |
| 15 | Effects of hydrogel/ silver coatings on in vitro adhesion to catheters of bacteria associated with urinary tract infection显示文摘 | AHEAM D G GRACE D T JENNINGS M J | 2000 | Curr Microbiol2000,41,2: | 1 |
| 16 | Customer-base anal- ysis in a discrete-time noncontractual setting 显示文摘 | Fader P S Hardie B G S Shang Jen | 2010 | Market- ing Science2010,29,6: | 1 |
| 17 | A field study of green roof hydrologic and water quality performance 显示文摘 | Hathway A M Hunt W F Jennings G D | 2008 | Transaction of the ASABE2008,51,1: | 1 |
| 18 | A Simple Fast Hybrid Pattern-matching Algorithm显示文摘 | Franek F Jennings C G Smyth P W F | 2007 | Journal of Discrete Algorithms2007,4,5: | 1 |
| 19 | Biomarkers for Parkinson's disease:tools to assess Parkinson's disease onset and progression显示文摘 | Marek K Jennings D Tamagnan G | 2008 | Ann Neurol2008,64,2: | 1 |
| 20 | PhaseⅢStudy of GemcitabinePlus Docetaxel Compared With Capecitabine Plus Docetaxel for An-thracycline Pretreated Patients With Metastatic Breast Cancer显示文摘 | Chan S Romieu G Huober Jens | 2009 | Journal of Clinical Oncology2009,27,11: | 1 |