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| 1 | Comparison of esophageal capsule endoscopy and esophagogastroduodenoscopy for diagnosis of esophageal varices显示文摘AIM: To investigate the utility of esophageal capsule endoscopy in the diagnosis and grading of esophageal varices. METHODS: Cirrhotic patients who were undergo-ing esophagogastroduodenoscopy (EGD) for variceal screening or surveillance underwent capsule endos-copy. Two separate blinded investigators read each capsule endoscopy for the following results: variceal grade, need for treatment with variceal banding or prophylaxis with beta-blocker therapy, degree of portal hypertensive gastropathy, and gastric varices. RESULTS: Fifty patients underwent both capsule and EGD. Forty-eight patients had both procedures on the same day, and 2 patients had capsule endoscopy within 72 h of EGD. The accuracy of capsule endos- copy to decide on the need for prophylaxis was 74%, with sensitivity of 63% and specificity of 82%. Inter-rater agreement was moderate (kappa = 0.56). Agree-ment between EGD and capsule endoscopy on grade of varices was 0.53 (moderate). Inter-rater reliability was good (kappa = 0.77). In diagnosis of portal hyper-tensive gastropathy, accuracy was 57%, with sensitiv-ity of 96% and specificity of 17%. Two patients had gastric varices seen on EGD, one of which was seen on capsule endoscopy. There were no complications from capsule endoscopy.CONCLUSION: We conclude that capsule endoscopy has a limited role in deciding which patients would benefit from EGD with banding or beta-blocker thera-py. More data is needed to assess accuracy for staging esophageal varices, PHG, and the detection of gastric varices. | Catherine T Frenette John G Kuldau Donald J Hillebrand Jill Lane Paul J Pockros | 2008 | World Journal of Gastroenterology2008，14，28： | 7 |
| 2 | Hepatic intra-arterial infusion of yttrium-90 microspheres in the treatment of recurrent hepatocellular carcinoma after liver transplantation: A case report显示文摘Hepatocellular carcinoma (HCC) recurs with a reported frequency of 12%-18% after liver transplantation. Recurrence is associated with a mortality rate exceeding 75%. Approximately one-third of recurrences develop in the transplanted liver and are therefore amenable to local therapy. A variety of treatment modalities have been reported including resection, transarterial chemo- embolization (TACE), radiofrequency ablation (RFA), ethanol ablation, cryoablation, and external beam irradiation. Goals of treatment are tumor control and the minimization of toxic effect to functional parenchyma. Efficacy of treatment is mitigated by the need for ongoing immunosuppression. Yttrium-90 microspheres have been used as a treatment modality both for primary HCC and for pre-transplant management of HCC with promising results. Twenty-two months after liver transplantation for hepatitis C cirrhosis complicated by HCC, a 42-year old man developed recurrence of HCC in his transplant allograft. Treatment of multiple right lobe lesions with anatomic resection and adjuvant chemotherapy was unsuccessful. Multifocal recurrence in the remaining liver allograft was treated with hepatic intra-arterial infusion of yttrium-90 microspheres (SIR-Spheres, Sirtex Medica Inc., Lake Forest, IL, USA). Efficacy was demonstrated by tumor necrosis on imaging and a decrease in alpha-fetoprotein (AFP) level. There were no adverse consequences of initial treatment. | Louis Rivera Huan Giap William Miller Jonathan Fisher Donald J Hillebrand Christopher Marsh Randolph L Schaffer | 2006 | World Journal of Gastroenterology2006，12，35： | 6 |
| 3 | Neglecting parameter changes in GARCH models 显示文摘 | Hillebrand E | 2005 | Journal of Econometrics2005，，129： | 1 |
| 4 | The relationship between in- ternal and external cooperation: literature review and prop- ositions 显示文摘 | Hillebrand B Biemans W G | 2003 | Journal of Business Research2003，56，9： | 1 |
| 5 | Development of a digital imaging system for objective measurement of hyper pigmented spots on the face显示文摘 | Miyamoto K Takiwaki H Hillebrand G | 2002 | Skin Res Technol2002，8，4： | 1 |
| 6 | Tumor necrosis factor, interleukine-6 and nitric oxide in sterile asctic fluid and serum from patients with cirrhosis who subsequently develop asctic fluid infection显示文摘 | Such J Hillebrand DJ Guarner C | 2001 | Dig Dis Sci2001，46，11： | 1 |
| 7 | Interaction of kaempferol with human serum albumin: A fluorescence and circular dichroismstudy 显示文摘 | MATEI I HILLEBRAND M | 2010 | Journal of Pharmaceutical and Biomedical Analysis2010，51，3： | 1 |
| 8 | Effective intrahepatic CD8+ T-cell immune responses are induced by low but not high numbers of antigen-expressing hepatocytes显示文摘 | Aaron Ochel Marcin Cebula Mathias Riehn Upneet Hillebrand Christoph Lipps Reinhold Schirmbeck Hansjorg Hauser Dagmar Wirth | 2016 | Cellular & Molecular Immunology2016，13，6： | 1 |
| 9 | Neuropeptides, food intake and body weight regulation: A hypothalamic focus显示文摘 | HILLEBRAND J J G DEWIED D ADAN R A H | 2002 | Peptides2002，23，： | 1 |
| 10 | Origin of vascular smooth muscle cells and the role of circulating stem cells in transplant arteriosclerosis 显示文摘 | Hillebrands JL Klatter FA Rozing J | 2003 | Arterioscler Thromb Vasc Biol2003，23，3： | 1 |
| 11 | Nebivolol decreases endothelial cell stiffness via the estrogen receptor beta: a nano-imaging study 显示文摘 | HILLEBRAND U LANG D TELGMANN R G | 2009 | J Hypertens2009，27，3： | 1 |
| 12 | The expansion of renewable energies and employment effects in Germany显示文摘 | B Hillebrand H G Buttermann J M Behringer | 2006 | Energy Policy2006，34，18： | 1 |
| 13 | The MELD score predicts the short-term and overall survival after liver transplantation in patients with primary sclerosing cholangitis or autoimmune liver diseases显示文摘 | Hoffmann K Hinz U Hillebrand N | 2014 | Langenbecks Arch Surg2014，399，8： | 1 |
| 14 | A polymorphism in the3'untranslated region of the CCK gene is associated with anorexia nervosa in Dutch patients显示文摘 | de KM Hendriks J Hillebrand J | 2006 | Psychiatr Genet2006，16，： | 1 |
| 15 | Simultaneous misalignment correction for approximate circular cone-beam computed tomo- grapby显示文摘 | Kyriakou Y Lapp R M Hillebrand L | 2008 | Physics in Medicine and Biology2008，53，22： | 1 |
| 16 | Intrameal hepatic portal and intraperitoneal infusions of glucagon like peptide-1 reduce spontaneous meal size in the rat via differen mechanisms显示文摘 | Ruttimann EB Arnold M Hillebrand JJ | 2009 | Endocrinology2009，150，3： | 1 |
| 17 | Spontaneous bacterial peritonitis显示文摘 | Hillebrand DJ | 2002 | Curr Treat Options Gastroenterol2002，5，6： | 1 |
| 18 | The nutrient stoichiometry of benthicmicroalgal growth:redfield proportions are optimal显示文摘 | Hillebrand H Sommer U | 1999 | Limonology and Oceanography1999，44，2： | 1 |
| 19 | High speed camera system using a CMOS image sensor显示文摘 | Hillebrand M Stevanovic N Hosticka B J | 2000 | Proceedings of the IEEE2000，，： | 1 |
| 20 | Dipyridylamine Ligands - Synthesis, Coordination Chemistry of the Group 10 Metals and Application of Nickel Complexes in Ethylene Oligomerization 显示文摘 | Schareina T Hillebrand G Fuhrmann H | 2001 | European Journal of the Inorganic Chemistry2001，，： | 1 |
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