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| 1 | Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients. | Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton | 2008 | World Journal of Gastroenterology2008，14，3： | 4 |
| 2 | Vascular endothelial growth factor-D expression is an independent prognostic maker for survival in cotorectal carcinoma显示文摘 | White J D Hewett P W Kosuge D | | 0，，： | 2 |
| 3 | Electromagnetic Direct Implicit Plasma Simulation显示文摘 | Hewett D W Langdon A B | 1987 | Journal of Computational Physics1987，72，： | 1 |
| 4 | Vascular endothelial growth factor-D expression independent prognostic marker for survival in colorectal carcinoma显示文摘 | White JD Hewett PW Kosuge D | 2002 | Cancer Res2002，62，6： | 1 |
| 5 | Re-duced greasiness of ‘ Granny Smith ’ apples washed in Tween 20 so-lution显示文摘 | DADZIE B K BANKS N H HEWETT E W CLELAND D J | 1995 | New Zealand Journal of Crop and Horticultural Science1995，23，2： | 1 |
| 6 | Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in colorectal carcinoma显示文摘 | Hewett PW Kosuge D | 2002 | Cancer Res2002，62，6： | 1 |
| 7 | Investigatingsingle nucleotide polymorphism (SNP) density in thehuman genome and its implications for molecularevolution 显示文摘 | Zhao Z M Fu Y X Hewett E D | 2003 | Gene2003，312，： | 1 |
| 8 | The Relationship of Hamstrings and Quadriceps Strength to Anterior Cruciate Ligament Injury in Female Athletes显示文摘 | Gregory D Myer Kevin R Ford Kim D Barber Foss Chunyan Liu Todd G Nick Timothy E Hewett | 2009 | Clinical Journal of Sport Medicine2009，，1： | 1 |
| 9 | Neuromuscular Training Techniques to Target Deficits Before Return to Sport After Anterior Cruciate Ligament Reconstruction显示文摘 | Gregory D Myer Mark V Paterno Kevin R Ford Timothy E Hewett | 2008 | Journal of Strength and Conditioning Research2008，，3： | 1 |
| 10 | Quenching rate constants of NCl(a) at room temperature显示文摘 | Hewett K J Manke II G C Setser D W | 2000 | J Phys Chem A2000，104，3： | 1 |
| 11 | Vascular endothelial growth factor-D expression is an indepent proghostic marker for survival in colorectal carcinoma显示文摘 | White JD Hewett PW Kosuge D | 2002 | Cancer Res2002，62，6： | 1 |
| 12 | Cap-fitted colonoscopy:a randomized,tandem colonoscopy study of adenoma miss rates显示文摘 | HEWETT D G REX D K | 2010 | Gastrointest Endosc2010，72，4： | 1 |
| 13 | Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in eolorectal carcinoma 显示文摘 | White J D Hewett P W Kosuge D | 2002 | Cancer Res2002，62，6： | 1 |
| 14 | Vascular endothe lial growth factor-D expression is an independent prognostic marker for surviva l in colorectal carcinoma显示文摘 | White JD Hewett PW Kosuge D | 2002 | Cancer Res2002，62，6： | 1 |
| 15 | Functional diversity, conservation and convergence in the evolution of the a -, 13 -, and y-carbonic anhydrase gene families 显示文摘 | Hewett E D Tashian R E | 1996 | Mol Phylogenet Evol1996，5，： | 1 |
| 16 | A reviewof electromyographic activation levels, timing differences, andincreased anterior cruciate ligament injury incidence in femaleathletes显示文摘 | HEWETT T E ZAZULAK B T MYER G D | 2005 | Brit J Sports Med2005，39，6： | 1 |
| 17 | Potentiation of oxygen-glucose deprivation-induced neuronal death after induction of iNOS 显示文摘 | Hewett SJ Muir JK Lobner D | 1996 | Stroke1996，27，9： | 1 |
| 18 | 1Vascular endothelial growth factorD expression is an independent prognosticmarker for survival in colorectalcarcinoma显示文摘 | White JD Hewett PW Kosuge D | 2002 | 1Cancer Res2002，62，： | 1 |
| 19 | Biomechanical measures of neuromuscular control and valgus loading of the knee predict anterior cruciate ligament injury risk in female athletes: a prospective study显示文摘 | Hewett T E Myer G D Ford K R | 2005 | American Journal of Sports Medicine2005，33，： | 1 |
| 20 | Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in colorectal carcinoma显示文摘 | White J D Hewett P W Kosuge D | 2002 | Cancer Res2002，62，6： | 1 |
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