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| 1 | Gastrotomy closure with a new tissue anchoring device:A porcine survival study显示文摘AIM: To evaluate the feasibility, reproducibility and efficacy of a new tissue anchoring device in a porcine survival model. METHODS: Gastrotomies were performed using a needle-knife and balloon dilator in 10 female Yorkshire pigs weighing 30-35 kg. Gastric closure was attempted using a new tissue anchoring device. The tightness of the closure was confirmed by means of air insufflation and the ability to maintain gastric distension with stability in peritoneal pressure measured with a Veress needle. All animals were monitored daily for signs of peritonitis and sepsis over 14 d. During necropsy, the peritoneal cavity and the gastric access site were examined.RESULTS: Transgastric access, closure and 14 d survival was achieved in all pigs. The mean closure time was 18.1 ± 19.2 min and a mean of 2.1 ± 1 devices were used. Supplementary clips were necessary in 2 cases. The closure time was progressively reduced (24.8 ± 13.9 min in the first 5 pigs vs 11.4 ± 5.9 min in the last 5, P = NS). At necropsy, the gastric access site was correctly closed in all cases with all brace-bars present. One device was misplaced in the mesocolon. Minimal adhesions were observed in 3 pigs and signs of mild peritonitis and adhesions in one. CONCLUSIONS: The use of this new tissue anchoring device in porcine stomachs is feasible, reproducible and effective and requires a short learning curve. | Carlos Guarner-Argente Henry Córdova Graciela Martínez-Pallí Ricard Navarro-Ripoll Antonio Rodríguez-d’Jesús Cristina Rodríguez de Miguel Mireia Beltrán Gloria Fernández-Esparrach | 2011 | World Journal of Gastroenterology2011，17，13： | 0 |
| 2 | Infection during Natural Orifice Transluminal Endoscopic Surgery Peritoneoscopy: A Randomized Comparative Study in a Survival Porcine Model显示文摘 | Carlos Guarner-Argente Mireia Beltrán Graciela Martínez-Pallí Ricard Navarro-Ripoll M. àngels Martínez-Zamora Henry Córdova Jaume Comas Cristina Rodríguez de Miguel Antonio Rodríguez-D’Jesús Manel Almela Clara Hernández-Cera Antonio M. Lacy Gloria Fernánd | 2011 | The Journal of Minimally Invasive Gynecology2011，，6： | 1 |
| 3 | 基于罗马Ⅳ标准的肝移植患者胆管括约肌疾病的发生率和临床结局显示文摘背景:目前对肝移植患者胆管括约肌疾病的认识严重不足。本研究旨在描述基于最新修订的罗马Ⅳ标准,肝移植患者乳头狭窄(PS)和胆管括约肌功能障碍(FBSD)的发生率和临床结局。方法:筛选2003年1月至2019年12月间接受内镜逆行性胆胰管造影(ERCP)的肝移植患者,从电子病历和内镜数据库中提取其临床资料及内镜发现,并收集ERCP检查时及ERCP术后1个月的实验室检查结果和临床结局。结果:在1,307例肝移植患者中,336例接受了849次ERCP。13例(1.0%)符合罗马Ⅳ的PS诊断标准[既往称为Oddi括约肌功能障碍(ODS)Ⅰ型],14例(1.0%)符合FBSD诊断标准(既往称为SOD Ⅱ型)。13例PS患者和10例FBSD患者接受了胆管狭窄成形术,术后1个月,分别有85%、61%和92%的PS患者总胆红素(P=0.019)、γ谷氨酰转移酶(P=0.087)和碱性磷酸酶(P=0.003)下降,而在FBSD患者,上述指标下降的患者比例分别为50%(P=0.721)、70%(P=0.013)和80%(P=0.093)。所有最初疑似BFSD的14例患者在随访中均调整了最终诊断。结论:肝移植术后PS的发生并不常见,发生率仅1%。我们的数据并不支持肝移植术后FBSD的诊断。狭窄成形术治疗肝移植术后PS患者安全有效。 | Alejandro Fernandez-Simon Oriol Sendino Karina Chavez-Rivera Henry Córdova Jordi Colmenero Gonzalo Crespo Yilliam Fundora Franco Samaniego Pablo Ruiz Constantino Fondevila Miquel Navasa Andrés Cárdenas | 2021 | Gastroenterology Report2021，9，4： | 0 |
| 4 | rate of adverse events of gastroduodenal snare polypectomy for non-flat polyp is low: A prospective and multicenter study显示文摘AIM To evaluate the rate of adverse events(AEs) during consecutive gastric and duodenal polypectomies in several Spanish centers. METHODS Polypectomies of protruded gastric or duodenal polyps ≥ 5 mm using hot snare were prospectively included. Prophylactic measures of hemorrhage were allowed in predefined cases. AEs were defined and graded according to the lexicon recommended by the American Society for Gastrointestinal Endoscopy. Patients were followed for 48 h, one week and 1 mo after theprocedure. RESULTS308 patients were included and a single polypectomy was performed in 205. Only 36(11.7%) were on prior anticoagulant therapy. Mean polyp size was 15 ± 8.9 mm(5-60) and in 294 cases(95.4%) were located in the stomach. Hemorrhage prophylaxis was performed in 219(71.1%) patients. Nine patients presented AEs(2.9%), and 6 of them were bleeding(n = 6, 1.9%)(in 5 out of 6 AE, different types of endoscopic treatment were performed). Other 24 hemorrhagic episodes could be managed without any change in the outcome of the endoscopy and, consequently, were considered incidents. We did not find any independent risk factor of bleeding.CONCLUSION Gastroduodenal polypectomy using prophylactic measures has a rate of AEs small enough to consider this procedure a safe and effective method for polyp resection independently of the polyp size and location. | Henry Córdova Lidia Argüello Carme Loras Antonio Naranjo Rodríguez Faust Riu Pons Joan B Gornals David Nicolás-Pérez Xavier Andújar Murcia Luis Hernández Santos Santolaria Carles Leal Carles Pons Enrique Pérez-Cuadrado-Robles Orlando García-Bosch Michel Papo Berger José Luis Ulla Rocha Cristina Sánchez-Montes Gloria Fernández-Esparrach | 2017 | World Journal of Gastroenterology2017，23，47： | 3 |
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